Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

pH-response regulator protein palH/RIM21

Gene

RIM21

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.By similarity

GO - Biological processi

  • cellular response to alkaline pH Source: CGD
  • cellular response to lithium ion Source: CGD
  • cellular response to neutral pH Source: CGD
  • cellular response to pH Source: CGD
  • filamentous growth Source: CGD
  • filamentous growth of a population of unicellular organisms in response to neutral pH Source: CGD

Names & Taxonomyi

Protein namesi
Recommended name:
pH-response regulator protein palH/RIM21
Gene namesi
Name:RIM21
Ordered Locus Names:CAALFM_C501950CA
ORF Names:CaO19.10686, CaO19.3176
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 5

Organism-specific databases

CGDiCAL0000199829 RIM21

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 96ExtracellularSequence analysisAdd BLAST96
Transmembranei97 – 117HelicalSequence analysisAdd BLAST21
Topological domaini118 – 130CytoplasmicSequence analysisAdd BLAST13
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Topological domaini152 – 172ExtracellularSequence analysisAdd BLAST21
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 204CytoplasmicSequence analysisAdd BLAST11
Transmembranei205 – 225HelicalSequence analysisAdd BLAST21
Topological domaini226 – 241ExtracellularSequence analysisAdd BLAST16
Transmembranei242 – 262HelicalSequence analysisAdd BLAST21
Topological domaini263 – 273CytoplasmicSequence analysisAdd BLAST11
Transmembranei274 – 294HelicalSequence analysisAdd BLAST21
Topological domaini295 – 298ExtracellularSequence analysis4
Transmembranei299 – 319HelicalSequence analysisAdd BLAST21
Topological domaini320 – 529CytoplasmicSequence analysisAdd BLAST210

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000581971 – 529pH-response regulator protein palH/RIM21Add BLAST529

Proteomic databases

PRIDEiQ59YK4

Family & Domainsi

Sequence similaritiesi

Belongs to the palH/RIM21 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ59YK4
OMAiCVVIPWE
OrthoDBiEOG092C27BG

Family and domain databases

InterProiView protein in InterPro
IPR014844 PalH
PANTHERiPTHR35779 PTHR35779, 1 hit
PfamiView protein in Pfam
PF08733 PalH, 1 hit

Sequencei

Sequence statusi: Complete.

Q59YK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYWKNAWWVG TVYSSCEPIE LPEGMLISKQ YETYPITTVS KAIYKQMCYR
60 70 80 90 100
NCIPVLNTNV GFVIDTFAKP LPIVSQSWRE FTKDSLRGSF AYSVVSIIYA
110 120 130 140 150
IAVSAVIIWF LTIFVLTNYT IKPSWLLKTS TILSTVYILV VVIKSILILH
160 170 180 190 200
GQQRDGYLHG AKLLSELNDY NPIQIIDLIV VLLLQINQVQ IIMRIFQRQK
210 220 230 240 250
DKRMALLIGI VATLASQVIW AIAQFYTPAD ANEASDILPA FIYLVRIAMA
260 270 280 290 300
LCYAAIITVF FISKIQIILA NKKIWLLTLL TFILIYSPVA FFVADVSNAF
310 320 330 340 350
VYELSEIFSV VNYVIGVVIP WEWCNKFNLI MKAKEKEGVL GRRFYEDELY
360 370 380 390 400
ELDRFELFVE EQMPEDEDNG DTHSDSPGNE LNGGAHHNSQ EQSDRLIGSN
410 420 430 440 450
SPTNKPHNGN NTDPTSRFRQ LLTNTKDAFL TLTDNIIAAG FAIPRSVSVS
460 470 480 490 500
TQSLTGRYRN NSTARTEYTK EVVPDFSPEM FLQPEGSSHI TETLSEQNAA
510 520
PSTTNSNHRR RNVYVYSRKE VILDVSSDE
Length:529
Mass (Da):60,057
Last modified:April 26, 2005 - v1
Checksum:iC6D88774DE73C239
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017627 Genomic DNA Translation: AOW29624.1
RefSeqiXP_714594.1, XM_709501.1

Genome annotation databases

EnsemblFungiiAOW29624; AOW29624; CAALFM_C501950CA
GeneIDi3643739
KEGGical:CAALFM_C501950CA

Similar proteinsi

Entry informationi

Entry nameiPALH_CANAL
AccessioniPrimary (citable) accession number: Q59YK4
Secondary accession number(s): A0A1D8PNA6, Q59YZ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health