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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei203Phosphocysteine intermediateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:CAALFM_C210190CA
ORF Names:CaO19.1762, CaO19.9331
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 2

Organism-specific databases

CGDiCAL0000196452. OCA1.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003333891 – 269Putative tyrosine-protein phosphatase OCA1Add BLAST269

Proteomic databases

PRIDEiQ59XY9.

Interactioni

Protein-protein interaction databases

BioGridi1227023. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ59XY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

InParanoidiQ59XY9.
OrthoDBiEOG092C4JKC.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
PfamiView protein in Pfam
PF03162. Y_phosphatase2. 1 hit.
SUPFAMiSSF52799. SSF52799. 2 hits.

Sequencei

Sequence statusi: Complete.

Q59XY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASITSNSQI LINNDSSTNK APTTNERQLR RINHPPNLRI VPPLNFCPVE
60 70 80 90 100
NQLYRSGQPS IINQSFLNQL NLKTIIWLSS EEPTDEFLEY CNDSSINIEY
110 120 130 140 150
LGMINEFNSE PATATTTDKQ SQSQSQSQSE EQKSQSQSQS QENQHHQFEQ
160 170 180 190 200
SDNNLLQDPS HLISSTIAKI NNNNPWDSLN ENTIKHALDL IVDKTNYPIL
210 220 230 240 250
ICCGMGRHRT GTVIGCLRRL QHWNLNSVSE EYRRFTGSRG GRILVELLIE
260
SFNIDLVNIN WELAPDWLK
Length:269
Mass (Da):30,723
Last modified:March 15, 2017 - v2
Checksum:i35F69F99C9B080FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017624 Genomic DNA. Translation: AOW27996.1.
RefSeqiXP_714407.2. XM_709314.2.

Genome annotation databases

EnsemblFungiiEAK95299; EAK95299; CaO19.9331.
EAK95340; EAK95340; CaO19.1762.
GeneIDi3643929.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017624 Genomic DNA. Translation: AOW27996.1.
RefSeqiXP_714407.2. XM_709314.2.

3D structure databases

ProteinModelPortaliQ59XY9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi1227023. 1 interactor.

Proteomic databases

PRIDEiQ59XY9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAK95299; EAK95299; CaO19.9331.
EAK95340; EAK95340; CaO19.1762.
GeneIDi3643929.

Organism-specific databases

CGDiCAL0000196452. OCA1.

Phylogenomic databases

InParanoidiQ59XY9.
OrthoDBiEOG092C4JKC.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiView protein in InterPro
IPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
PfamiView protein in Pfam
PF03162. Y_phosphatase2. 1 hit.
SUPFAMiSSF52799. SSF52799. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiOCA1_CANAL
AccessioniPrimary (citable) accession number: Q59XY9
Secondary accession number(s): A0A1D8PIN0, Q59XU3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: March 15, 2017
Last modified: April 12, 2017
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.