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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei203 – 2031Phosphocysteine intermediateBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
ORF Names:CaO19.1762, CaO19.9331
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559 Componenti: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0000898. orf19.1762.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Putative tyrosine-protein phosphatase OCA1PRO_0000333389Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi1227023. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ59XY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
InParanoidiQ59XY9.
KOiK18043.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 2 hits.

Sequencei

Sequence statusi: Complete.

Q59XY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASITSNPQI LINNDSSTNK APTTNERQLR RINHPPNLRI VPPLNFCPVE
60 70 80 90 100
NQLYRSGQPS IINQSFLNQL NLKTIIWLSS EEPTDEFLEY CNDSSINIEY
110 120 130 140 150
LGMINEFNSE PATATTTDKQ SQSQSQSQSE EQKSQSQSQS QENQHHQFEQ
160 170 180 190 200
SDNNLLQDPS HLISSTIAKI NNNNPWDSLN ENTIKHALDL IVDKTNYPIL
210 220 230 240 250
ICCGMGRHRT GTVIGCLRRL QHWNLNSVSE EYRRFTGSRG GRILVELLIE
260
SFNIDLVNIN WELAPDWLK
Length:269
Mass (Da):30,733
Last modified:April 26, 2005 - v1
Checksum:i35F73D09C9B03D6E
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti94 – 941S → L in allele CaO19.9331.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000104 Genomic DNA. Translation: EAK95340.1.
AACQ01000105 Genomic DNA. Translation: EAK95299.1.
RefSeqiXP_714367.1. XM_709274.1.
XP_714407.1. XM_709314.1.

Genome annotation databases

GeneIDi3643929.
3643991.
KEGGical:CaO19.1762.
cal:CaO19.9331.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000104 Genomic DNA. Translation: EAK95340.1.
AACQ01000105 Genomic DNA. Translation: EAK95299.1.
RefSeqiXP_714367.1. XM_709274.1.
XP_714407.1. XM_709314.1.

3D structure databases

ProteinModelPortaliQ59XY9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi1227023. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3643929.
3643991.
KEGGical:CaO19.1762.
cal:CaO19.9331.

Organism-specific databases

CGDiCAL0000898. orf19.1762.

Phylogenomic databases

eggNOGiCOG2365.
InParanoidiQ59XY9.
KOiK18043.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiOCA1_CANAL
AccessioniPrimary (citable) accession number: Q59XY9
Secondary accession number(s): Q59XU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 26, 2005
Last modified: June 24, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.