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Q59XY9

- OCA1_CANAL

UniProt

Q59XY9 - OCA1_CANAL

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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei203 – 2031Phosphocysteine intermediateBy similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: CGD

GO - Biological processi

  1. peptidyl-tyrosine dephosphorylation Source: GOC
  2. protein dephosphorylation Source: CGD
  3. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
ORF Names:CaO19.1762, CaO19.9331
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0000898. orf19.1762.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 269269Putative tyrosine-protein phosphatase OCA1PRO_0000333389Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi1227085. 1 interaction.
STRINGi5476.CAL0000898.

Structurei

3D structure databases

ProteinModelPortaliQ59XY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2365.
InParanoidiQ59XY9.
KOiK18043.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 2 hits.

Sequencei

Sequence statusi: Complete.

Q59XY9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASITSNPQI LINNDSSTNK APTTNERQLR RINHPPNLRI VPPLNFCPVE
60 70 80 90 100
NQLYRSGQPS IINQSFLNQL NLKTIIWLSS EEPTDEFLEY CNDSSINIEY
110 120 130 140 150
LGMINEFNSE PATATTTDKQ SQSQSQSQSE EQKSQSQSQS QENQHHQFEQ
160 170 180 190 200
SDNNLLQDPS HLISSTIAKI NNNNPWDSLN ENTIKHALDL IVDKTNYPIL
210 220 230 240 250
ICCGMGRHRT GTVIGCLRRL QHWNLNSVSE EYRRFTGSRG GRILVELLIE
260
SFNIDLVNIN WELAPDWLK
Length:269
Mass (Da):30,733
Last modified:April 26, 2005 - v1
Checksum:i35F73D09C9B03D6E
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti94 – 941S → L in allele CaO19.9331.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000104 Genomic DNA. Translation: EAK95340.1.
AACQ01000105 Genomic DNA. Translation: EAK95299.1.
RefSeqiXP_714367.1. XM_709274.1.
XP_714407.1. XM_709314.1.

Genome annotation databases

GeneIDi3643929.
3643991.
KEGGical:CaO19.1762.
cal:CaO19.9331.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000104 Genomic DNA. Translation: EAK95340.1 .
AACQ01000105 Genomic DNA. Translation: EAK95299.1 .
RefSeqi XP_714367.1. XM_709274.1.
XP_714407.1. XM_709314.1.

3D structure databases

ProteinModelPortali Q59XY9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 1227085. 1 interaction.
STRINGi 5476.CAL0000898.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3643929.
3643991.
KEGGi cal:CaO19.1762.
cal:CaO19.9331.

Organism-specific databases

CGDi CAL0000898. orf19.1762.

Phylogenomic databases

eggNOGi COG2365.
InParanoidi Q59XY9.
KOi K18043.
OrthoDBi EOG7Z0K6V.

Family and domain databases

Gene3Di 3.90.190.10. 2 hits.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view ]
Pfami PF03162. Y_phosphatase2. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiOCA1_CANAL
AccessioniPrimary (citable) accession number: Q59XY9
Secondary accession number(s): Q59XU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3