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Q59XY9

- OCA1_CANAL

UniProt

Q59XY9 - OCA1_CANAL

Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei203 – 2031Phosphocysteine intermediateBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: CGD

    GO - Biological processi

    1. peptidyl-tyrosine dephosphorylation Source: GOC
    2. protein dephosphorylation Source: CGD
    3. response to stress Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
    Gene namesi
    Name:OCA1
    ORF Names:CaO19.1762, CaO19.9331
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000898. orf19.1762.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 269269Putative tyrosine-protein phosphatase OCA1PRO_0000333389Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    BioGridi1227085. 1 interaction.
    STRINGi5476.CAL0000898.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59XY9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG2365.
    KOiK18043.
    OrthoDBiEOG7Z0K6V.

    Family and domain databases

    Gene3Di3.90.190.10. 2 hits.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view]
    PfamiPF03162. Y_phosphatase2. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q59XY9-1 [UniParc]FASTAAdd to Basket

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    MASITSNPQI LINNDSSTNK APTTNERQLR RINHPPNLRI VPPLNFCPVE    50
    NQLYRSGQPS IINQSFLNQL NLKTIIWLSS EEPTDEFLEY CNDSSINIEY 100
    LGMINEFNSE PATATTTDKQ SQSQSQSQSE EQKSQSQSQS QENQHHQFEQ 150
    SDNNLLQDPS HLISSTIAKI NNNNPWDSLN ENTIKHALDL IVDKTNYPIL 200
    ICCGMGRHRT GTVIGCLRRL QHWNLNSVSE EYRRFTGSRG GRILVELLIE 250
    SFNIDLVNIN WELAPDWLK 269
    Length:269
    Mass (Da):30,733
    Last modified:April 26, 2005 - v1
    Checksum:i35F73D09C9B03D6E
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti94 – 941S → L in allele CaO19.9331.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000104 Genomic DNA. Translation: EAK95340.1.
    AACQ01000105 Genomic DNA. Translation: EAK95299.1.
    RefSeqiXP_714367.1. XM_709274.1.
    XP_714407.1. XM_709314.1.

    Genome annotation databases

    GeneIDi3643929.
    3643991.
    KEGGical:CaO19.1762.
    cal:CaO19.9331.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000104 Genomic DNA. Translation: EAK95340.1 .
    AACQ01000105 Genomic DNA. Translation: EAK95299.1 .
    RefSeqi XP_714367.1. XM_709274.1.
    XP_714407.1. XM_709314.1.

    3D structure databases

    ProteinModelPortali Q59XY9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 1227085. 1 interaction.
    STRINGi 5476.CAL0000898.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3643929.
    3643991.
    KEGGi cal:CaO19.1762.
    cal:CaO19.9331.

    Organism-specific databases

    CGDi CAL0000898. orf19.1762.

    Phylogenomic databases

    eggNOGi COG2365.
    KOi K18043.
    OrthoDBi EOG7Z0K6V.

    Family and domain databases

    Gene3Di 3.90.190.10. 2 hits.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR004861. Tyr_Pase_SIW14-like.
    [Graphical view ]
    Pfami PF03162. Y_phosphatase2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiOCA1_CANAL
    AccessioniPrimary (citable) accession number: Q59XY9
    Secondary accession number(s): Q59XU3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3