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Q59XY9 (OCA1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative tyrosine-protein phosphatase OCA1

EC=3.1.3.48
Gene names
Name:OCA1
ORF Names:CaO19.1762, CaO19.9331
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative tyrosine-protein phosphatase required for protection against superoxide stress By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 269269Putative tyrosine-protein phosphatase OCA1
PRO_0000333389

Sites

Active site2031Phosphocysteine intermediate By similarity

Natural variations

Natural variant941S → L in allele CaO19.9331.

Sequences

Sequence LengthMass (Da)Tools
Q59XY9 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 35F73D09C9B03D6E

FASTA26930,733
        10         20         30         40         50         60 
MASITSNPQI LINNDSSTNK APTTNERQLR RINHPPNLRI VPPLNFCPVE NQLYRSGQPS 

        70         80         90        100        110        120 
IINQSFLNQL NLKTIIWLSS EEPTDEFLEY CNDSSINIEY LGMINEFNSE PATATTTDKQ 

       130        140        150        160        170        180 
SQSQSQSQSE EQKSQSQSQS QENQHHQFEQ SDNNLLQDPS HLISSTIAKI NNNNPWDSLN 

       190        200        210        220        230        240 
ENTIKHALDL IVDKTNYPIL ICCGMGRHRT GTVIGCLRRL QHWNLNSVSE EYRRFTGSRG 

       250        260 
GRILVELLIE SFNIDLVNIN WELAPDWLK 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000104 Genomic DNA. Translation: EAK95340.1.
AACQ01000105 Genomic DNA. Translation: EAK95299.1.
RefSeqXP_714367.1. XM_709274.1.
XP_714407.1. XM_709314.1.

3D structure databases

ProteinModelPortalQ59XY9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid1227085. 1 interaction.
STRING5476.CAL0000898.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3643929.
3643991.
KEGGcal:CaO19.1762.
cal:CaO19.9331.

Organism-specific databases

CGDCAL0000898. orf19.1762.

Phylogenomic databases

eggNOGCOG2365.
KOK18043.
OrthoDBEOG7Z0K6V.

Family and domain databases

Gene3D3.90.190.10. 2 hits.
InterProIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMSSF52799. SSF52799. 2 hits.
ProtoNetSearch...

Entry information

Entry nameOCA1_CANAL
AccessionPrimary (citable) accession number: Q59XY9
Secondary accession number(s): Q59XU3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 26, 2005
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names