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Q59XW9

- IR222_CANAL

UniProt

Q59XW9 - IR222_CANAL

Protein

Increased recombination centers protein 22-2

Gene

IRC22-2

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Is probably involved in a pathway contributing to genomic integrity.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Increased recombination centers protein 22-2
    Gene namesi
    Name:IRC22-2
    ORF Names:CaO19.1782, CaO19.9348
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000962. orf19.1782.
    CAL0062511. orf19.9348.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: CGD

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 239220Increased recombination centers protein 22-2PRO_0000399071Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0000962.

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini20 – 161142LumenalSequence AnalysisAdd
    BLAST
    Topological domaini183 – 23957CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei162 – 18221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IRC22 family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG40706.
    HOGENOMiHOG000248201.
    OrthoDBiEOG78M0CV.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q59XW9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLSTIFTAF AATIATVAGY ETTGSKQTVD ILIDYIIKET PELSQNDVAN    50
    WENGDTVTLQ YVVNNNEESE ITVVGVTGQF KNPINNEIVT NLTTGKVGPI 100
    AVPPGEAIKF DQKINVDLIP ANYELIPHVF IAQDSLIKVI PCRGQLATIV 150
    DAAVSFFDPR LIFLELVLLI TFAGLIYVGY EIWGKQYFKG VAPVKAKKVS 200
    AAKASSPVAT GPSTISATGY DTNWIPESHL KQKKTKKVN 239
    Length:239
    Mass (Da):25,976
    Last modified:April 26, 2005 - v1
    Checksum:i3028F889FE5FC302
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti210 – 2101T → S in allele CaO19.9348.
    Natural varianti215 – 2151I → T in allele CaO19.9348.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000105 Genomic DNA. Translation: EAK95316.1.
    AACQ01000104 Genomic DNA. Translation: EAK95360.1.
    RefSeqiXP_714384.1. XM_709291.1.
    XP_714427.1. XM_709334.1.

    Genome annotation databases

    GeneIDi3643962.
    3643974.
    KEGGical:CaO19.1782.
    cal:CaO19.9348.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000105 Genomic DNA. Translation: EAK95316.1 .
    AACQ01000104 Genomic DNA. Translation: EAK95360.1 .
    RefSeqi XP_714384.1. XM_709291.1.
    XP_714427.1. XM_709334.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0000962.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3643962.
    3643974.
    KEGGi cal:CaO19.1782.
    cal:CaO19.9348.

    Organism-specific databases

    CGDi CAL0000962. orf19.1782.
    CAL0062511. orf19.9348.

    Phylogenomic databases

    eggNOGi NOG40706.
    HOGENOMi HOG000248201.
    OrthoDBi EOG78M0CV.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiIR222_CANAL
    AccessioniPrimary (citable) accession number: Q59XW9
    Secondary accession number(s): Q59XS6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 5, 2010
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3