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Protein

Increased recombination centers protein 22-2

Gene

IRC22-2

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Is probably involved in a pathway contributing to genomic integrity.

Names & Taxonomyi

Protein namesi
Recommended name:
Increased recombination centers protein 22-2
Gene namesi
Name:IRC22-2
Ordered Locus Names:CAALFM_C210010CA
ORF Names:CaO19.1782, CaO19.9348
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 2

Organism-specific databases

CGDiCAL0000187589 orf19.1782

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini20 – 161LumenalSequence analysisAdd BLAST142
Transmembranei162 – 182HelicalSequence analysisAdd BLAST21
Topological domaini183 – 239CytoplasmicSequence analysisAdd BLAST57

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000039907120 – 239Increased recombination centers protein 22-2Add BLAST220

Family & Domainsi

Sequence similaritiesi

Belongs to the IRC22 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000248201
InParanoidiQ59XW9
OrthoDBiEOG092C4YR8

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q59XW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSTIFTAF AATIATVAGY ETTGSKQTVD ILIDYIIKET PELSQNDVAN
60 70 80 90 100
WENGDTVTLQ YVVNNNEESE ITVVGVTGQF KNPINNEIVT NLTTGKVGPI
110 120 130 140 150
AVPPGEAIKF DQKINVDLIP ANYELIPHVF IAQDSLIKVI PCRGQLATIV
160 170 180 190 200
DAAVSFFDPR LIFLELVLLI TFAGLIYVGY EIWGKQYFKG VAPVKAKKVS
210 220 230
AAKASSPVAT GPSTTSATGY DTNWIPESHL KQKKTKKVN
Length:239
Mass (Da):25,964
Last modified:March 15, 2017 - v2
Checksum:i2CF93589FE5FC302
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017624 Genomic DNA Translation: AOW27979.1
RefSeqiXP_714427.2, XM_709334.2

Genome annotation databases

EnsemblFungiiAOW27979; AOW27979; CAALFM_C210010CA
GeneIDi3643962
KEGGical:CAALFM_C210010CA

Similar proteinsi

Entry informationi

Entry nameiIR222_CANAL
AccessioniPrimary (citable) accession number: Q59XW9
Secondary accession number(s): A0A1D8PIM9, Q59XS6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: March 15, 2017
Last modified: May 23, 2018
This is version 51 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health