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Q59XW9 (IR222_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Increased recombination centers protein 22-2
Gene names
Name:IRC22-2
ORF Names:CaO19.1782, CaO19.9348
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Is probably involved in a pathway contributing to genomic integrity.

Subcellular location

Endoplasmic reticulum membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

Belongs to the IRC22 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 239220Increased recombination centers protein 22-2
PRO_0000399071

Regions

Topological domain20 – 161142Lumenal Potential
Transmembrane162 – 18221Helical; Potential
Topological domain183 – 23957Cytoplasmic Potential

Natural variations

Natural variant2101T → S in allele CaO19.9348.
Natural variant2151I → T in allele CaO19.9348.

Sequences

Sequence LengthMass (Da)Tools
Q59XW9 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 3028F889FE5FC302

FASTA23925,976
        10         20         30         40         50         60 
MKLSTIFTAF AATIATVAGY ETTGSKQTVD ILIDYIIKET PELSQNDVAN WENGDTVTLQ 

        70         80         90        100        110        120 
YVVNNNEESE ITVVGVTGQF KNPINNEIVT NLTTGKVGPI AVPPGEAIKF DQKINVDLIP 

       130        140        150        160        170        180 
ANYELIPHVF IAQDSLIKVI PCRGQLATIV DAAVSFFDPR LIFLELVLLI TFAGLIYVGY 

       190        200        210        220        230 
EIWGKQYFKG VAPVKAKKVS AAKASSPVAT GPSTISATGY DTNWIPESHL KQKKTKKVN 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000105 Genomic DNA. Translation: EAK95316.1.
AACQ01000104 Genomic DNA. Translation: EAK95360.1.
RefSeqXP_714384.1. XM_709291.1.
XP_714427.1. XM_709334.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0000962.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3643962.
3643974.
KEGGcal:CaO19.1782.
cal:CaO19.9348.

Organism-specific databases

CGDCAL0000962. orf19.1782.
CAL0062511. orf19.9348.

Phylogenomic databases

eggNOGNOG40706.
HOGENOMHOG000248201.
OrthoDBEOG78M0CV.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameIR222_CANAL
AccessionPrimary (citable) accession number: Q59XW9
Secondary accession number(s): Q59XS6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names