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Q59XW9

- IR222_CANAL

UniProt

Q59XW9 - IR222_CANAL

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Protein

Increased recombination centers protein 22-2

Gene

IRC22-2

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Is probably involved in a pathway contributing to genomic integrity.

Names & Taxonomyi

Protein namesi
Recommended name:
Increased recombination centers protein 22-2
Gene namesi
Name:IRC22-2
ORF Names:CaO19.1782, CaO19.9348
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0000962. orf19.1782.
CAL0062511. orf19.9348.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 239220Increased recombination centers protein 22-2PRO_0000399071Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0000962.

Structurei

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini20 – 161142LumenalSequence AnalysisAdd
BLAST
Topological domaini183 – 23957CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei162 – 18221HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the IRC22 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG40706.
HOGENOMiHOG000248201.
InParanoidiQ59XW9.
OrthoDBiEOG78M0CV.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q59XW9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLSTIFTAF AATIATVAGY ETTGSKQTVD ILIDYIIKET PELSQNDVAN
60 70 80 90 100
WENGDTVTLQ YVVNNNEESE ITVVGVTGQF KNPINNEIVT NLTTGKVGPI
110 120 130 140 150
AVPPGEAIKF DQKINVDLIP ANYELIPHVF IAQDSLIKVI PCRGQLATIV
160 170 180 190 200
DAAVSFFDPR LIFLELVLLI TFAGLIYVGY EIWGKQYFKG VAPVKAKKVS
210 220 230
AAKASSPVAT GPSTISATGY DTNWIPESHL KQKKTKKVN
Length:239
Mass (Da):25,976
Last modified:April 26, 2005 - v1
Checksum:i3028F889FE5FC302
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti210 – 2101T → S in allele CaO19.9348.
Natural varianti215 – 2151I → T in allele CaO19.9348.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000105 Genomic DNA. Translation: EAK95316.1.
AACQ01000104 Genomic DNA. Translation: EAK95360.1.
RefSeqiXP_714384.1. XM_709291.1.
XP_714427.1. XM_709334.1.

Genome annotation databases

GeneIDi3643962.
3643974.
KEGGical:CaO19.1782.
cal:CaO19.9348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000105 Genomic DNA. Translation: EAK95316.1 .
AACQ01000104 Genomic DNA. Translation: EAK95360.1 .
RefSeqi XP_714384.1. XM_709291.1.
XP_714427.1. XM_709334.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0000962.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3643962.
3643974.
KEGGi cal:CaO19.1782.
cal:CaO19.9348.

Organism-specific databases

CGDi CAL0000962. orf19.1782.
CAL0062511. orf19.9348.

Phylogenomic databases

eggNOGi NOG40706.
HOGENOMi HOG000248201.
InParanoidi Q59XW9.
OrthoDBi EOG78M0CV.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiIR222_CANAL
AccessioniPrimary (citable) accession number: Q59XW9
Secondary accession number(s): Q59XS6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3