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Q59XW4

- Q59XW4_CANAL

UniProt

Q59XW4 - Q59XW4_CANAL

Protein

Acetyl-coenzyme A synthetase

Gene

ACS1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

    GO - Molecular functioni

    1. acetate-CoA ligase activity Source: CGD
    2. AMP binding Source: InterPro

    GO - Biological processi

    1. acetate metabolic process Source: CGD
    2. acetyl-CoA biosynthetic process Source: CGD
    3. acetyl-CoA biosynthetic process from acetate Source: InterPro

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
    Gene namesi
    Name:ACS1Imported
    ORF Names:CaO19.1743Imported, CaO19.9310Imported
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000855. ACS1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: CGD

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0000855.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59XW4.
    SMRiQ59XW4. Positions 38-670.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

    Phylogenomic databases

    KOiK01895.
    OrthoDBiEOG7M3J82.

    Family and domain databases

    InterProiIPR011904. Ac_CoA_lig.
    IPR025110. AMP-bd_C.
    IPR020845. AMP-binding_CS.
    IPR000873. AMP-dep_Synth/Lig.
    [Graphical view]
    PfamiPF00501. AMP-binding. 1 hit.
    PF13193. AMP-binding_C. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
    PROSITEiPS00455. AMP_BINDING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q59XW4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPESTQQSHL SLDHEKMQQP PKGFTERSKT KPNLPDFETY QKLYKQSIEN    50
    PNEFFTQQAK ENLDWFKPFD LARFPIDPKD DYKNGDLPAW FINGQLNACY 100
    NAVDRWAIKN PDKPAIIYEG DEPDQGRIIT YGELLKQVSK LAQALTKLGV 150
    KKGDSVAVYL PMIPEAIVTL LAIVRIGAMH SVVFAGFSSA SLRDRILDAD 200
    SRIVITADES KRGGKTIETK KIVDDALKEC PKVRNVIVFK RTGNSHVPFS 250
    PGRDLWWHDE MAKYGPYFPP VPVNSEDPLF LLYTSGSTGK PKGVQHNTAG 300
    YLLGAVLTTK YTFDVHEDDI LFTAGDIGWI TGHTYCVYGP LLAGATSVVF 350
    EGTPAYPNYS RYWEIVDKYK VNQFYVAPTA LRLLKRAGTK YVEKYDLSSL 400
    RVLGSVGEPI AAEVWHWYND NIGRGQAHIV DTYWQTESGS HLLTPLAGIT 450
    PTKPGSASLP FFGVDPKILD PTTGEELPDN DVEGVLAIKS AWPSITRGIY 500
    NDYNRFIDTY LAPYANYYFS GDGAARDRDG FYWILGRVDD VVNVSGHRLS 550
    TAEIEAALIE HPIVGESAVV GYADELTGQA VAAYVSLKKD KAVGEDVENI 600
    KKEMILTVRK EIGPFAAPKM ILLVDDLPKT RSGKIMRRIL RKVLAGEEDQ 650
    LGDISTLSNP GVVQQIIDVV HHAKK 675
    Length:675
    Mass (Da):75,140
    Last modified:April 26, 2005 - v1
    Checksum:i3D54EC14B45F7EF7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000105 Genomic DNA. Translation: EAK95278.1.
    AACQ01000104 Genomic DNA. Translation: EAK95321.1.
    RefSeqiXP_714347.1. XM_709254.1.
    XP_714389.1. XM_709296.1.

    Genome annotation databases

    GeneIDi3643941.
    3643993.
    KEGGical:CaO19.1743.
    cal:CaO19.9310.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000105 Genomic DNA. Translation: EAK95278.1 .
    AACQ01000104 Genomic DNA. Translation: EAK95321.1 .
    RefSeqi XP_714347.1. XM_709254.1.
    XP_714389.1. XM_709296.1.

    3D structure databases

    ProteinModelPortali Q59XW4.
    SMRi Q59XW4. Positions 38-670.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0000855.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3643941.
    3643993.
    KEGGi cal:CaO19.1743.
    cal:CaO19.9310.

    Organism-specific databases

    CGDi CAL0000855. ACS1.

    Phylogenomic databases

    KOi K01895.
    OrthoDBi EOG7M3J82.

    Family and domain databases

    InterProi IPR011904. Ac_CoA_lig.
    IPR025110. AMP-bd_C.
    IPR020845. AMP-binding_CS.
    IPR000873. AMP-dep_Synth/Lig.
    [Graphical view ]
    Pfami PF00501. AMP-binding. 1 hit.
    PF13193. AMP-binding_C. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02188. Ac_CoA_lig_AcsA. 1 hit.
    PROSITEi PS00455. AMP_BINDING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876Imported.

    Entry informationi

    Entry nameiQ59XW4_CANAL
    AccessioniPrimary (citable) accession number: Q59XW4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3