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Q59XW4

- Q59XW4_CANAL

UniProt

Q59XW4 - Q59XW4_CANAL

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Protein
Acetyl-coenzyme A synthetase
Gene
ACS1, CaO19.1743, CaO19.9310
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

  1. AMP binding Source: InterPro
  2. acetate-CoA ligase activity Source: CGD

GO - Biological processi

  1. acetate metabolic process Source: CGD
  2. acetyl-CoA biosynthetic process Source: CGD
  3. acetyl-CoA biosynthetic process from acetate Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
Name:ACS1Imported
ORF Names:CaO19.1743Imported, CaO19.9310Imported
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0000855. ACS1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: CGD
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0000855.

Structurei

3D structure databases

ProteinModelPortaliQ59XW4.
SMRiQ59XW4. Positions 38-670.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59XW4-1 [UniParc]FASTAAdd to Basket

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MPESTQQSHL SLDHEKMQQP PKGFTERSKT KPNLPDFETY QKLYKQSIEN    50
PNEFFTQQAK ENLDWFKPFD LARFPIDPKD DYKNGDLPAW FINGQLNACY 100
NAVDRWAIKN PDKPAIIYEG DEPDQGRIIT YGELLKQVSK LAQALTKLGV 150
KKGDSVAVYL PMIPEAIVTL LAIVRIGAMH SVVFAGFSSA SLRDRILDAD 200
SRIVITADES KRGGKTIETK KIVDDALKEC PKVRNVIVFK RTGNSHVPFS 250
PGRDLWWHDE MAKYGPYFPP VPVNSEDPLF LLYTSGSTGK PKGVQHNTAG 300
YLLGAVLTTK YTFDVHEDDI LFTAGDIGWI TGHTYCVYGP LLAGATSVVF 350
EGTPAYPNYS RYWEIVDKYK VNQFYVAPTA LRLLKRAGTK YVEKYDLSSL 400
RVLGSVGEPI AAEVWHWYND NIGRGQAHIV DTYWQTESGS HLLTPLAGIT 450
PTKPGSASLP FFGVDPKILD PTTGEELPDN DVEGVLAIKS AWPSITRGIY 500
NDYNRFIDTY LAPYANYYFS GDGAARDRDG FYWILGRVDD VVNVSGHRLS 550
TAEIEAALIE HPIVGESAVV GYADELTGQA VAAYVSLKKD KAVGEDVENI 600
KKEMILTVRK EIGPFAAPKM ILLVDDLPKT RSGKIMRRIL RKVLAGEEDQ 650
LGDISTLSNP GVVQQIIDVV HHAKK 675
Length:675
Mass (Da):75,140
Last modified:April 26, 2005 - v1
Checksum:i3D54EC14B45F7EF7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000105 Genomic DNA. Translation: EAK95278.1.
AACQ01000104 Genomic DNA. Translation: EAK95321.1.
RefSeqiXP_714347.1. XM_709254.1.
XP_714389.1. XM_709296.1.

Genome annotation databases

GeneIDi3643941.
3643993.
KEGGical:CaO19.1743.
cal:CaO19.9310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000105 Genomic DNA. Translation: EAK95278.1 .
AACQ01000104 Genomic DNA. Translation: EAK95321.1 .
RefSeqi XP_714347.1. XM_709254.1.
XP_714389.1. XM_709296.1.

3D structure databases

ProteinModelPortali Q59XW4.
SMRi Q59XW4. Positions 38-670.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0000855.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3643941.
3643993.
KEGGi cal:CaO19.1743.
cal:CaO19.9310.

Organism-specific databases

CGDi CAL0000855. ACS1.

Phylogenomic databases

KOi K01895.
OrthoDBi EOG7M3J82.

Family and domain databases

InterProi IPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view ]
Pfami PF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEi PS00455. AMP_BINDING. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiQ59XW4_CANAL
AccessioniPrimary (citable) accession number: Q59XW4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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