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Q59X94 (CCPR2_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative heme-binding peroxidase

EC=1.11.1.-
Gene names
Name:CCP2
ORF Names:CaO19.584, CaO19.8216
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Sequence similarities

Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

Ontologies

Keywords
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
Gene Ontology (GO)
   Biological processresponse to oxidative stress

Inferred from electronic annotation. Source: InterPro

   Molecular functionheme binding

Inferred from electronic annotation. Source: InterPro

peroxidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 291291Putative heme-binding peroxidase
PRO_0000055584

Sites

Active site611Proton acceptor By similarity
Active site2011Tryptophan radical intermediate By similarity
Metal binding1851Iron (heme axial ligand) By similarity
Site571Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
Q59X94 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 50EC570C6615D744

FASTA29132,918
        10         20         30         40         50         60 
MIRSYIRNII LAILSPLLTT PPPLILPPPY EKIIQEITTV LSINNYDDGS LAPIILRLAW 

        70         80         90        100        110        120 
HCCATYDVTT NTGGSNGATM RFVPEITDEG NYGLDIARAA LEPIKQRYPA ISYADLWTLA 

       130        140        150        160        170        180 
GKVAIEYMGG PTIIWKSGRV DYTNDRCTPS NGLLPFADKD ANHIRKTFTR LGYNDQQTVA 

       190        200        210        220        230        240 
LIGAHGVGRC HKRFSGWEGK WTRTPKTFSN QFYVVLLNET WSQGEVPETG KTQYFNADKS 

       250        260        270        280        290 
LIMLNTDMEL IRDKSYLHWV EIYAKDEPKF FHDFSSAFAK LLELGIKRET L 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000109 Genomic DNA. Translation: EAK95087.1.
AACQ01000108 Genomic DNA. Translation: EAK95134.1.
RefSeqXP_714170.1. XM_709077.1.
XP_714211.1. XM_709118.1.

3D structure databases

ProteinModelPortalQ59X94.
ModBaseSearch...

Protein family/group databases

PeroxiBase2345. CalCcP01.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3644127.
3644156.
KEGGcal:CaO19.584.
cal:CaO19.8216.

Organism-specific databases

CGDCAL0000335. orf19.584.

Phylogenomic databases

PhylomeDBQ59X94.

Family and domain databases

InterProIPR002207. Asc_peroxidase.
IPR010255. Haem_peroxidase.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
[Graphical view]
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00459. ASPEROXIDASE.
PR00458. PEROXIDASE.
SUPFAMSSF48113. Peroxidase_super. 1 hit.
PROSITEPS00435. PEROXIDASE_1. False negative.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCCPR2_CANAL
AccessionPrimary (citable) accession number: Q59X94
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families