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Protein

Plasma membrane fusion protein PRM1

Gene

PRM1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Conjugation

Names & Taxonomyi

Protein namesi
Recommended name:
Plasma membrane fusion protein PRM1
Gene namesi
Name:PRM1
ORF Names:CaO19.669, CaO19.8286
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 19ExtracellularBy similarityAdd BLAST19
Transmembranei20 – 40HelicalSequence analysisAdd BLAST21
Topological domaini41 – 92CytoplasmicBy similarityAdd BLAST52
Transmembranei93 – 113HelicalSequence analysisAdd BLAST21
Topological domaini114 – 281ExtracellularBy similarityAdd BLAST168
Transmembranei282 – 302HelicalSequence analysisAdd BLAST21
Topological domaini303 – 365CytoplasmicBy similarityAdd BLAST63
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Topological domaini387 – 537ExtracellularBy similarityAdd BLAST151
Transmembranei538 – 558HelicalSequence analysisAdd BLAST21
Topological domaini559 – 623CytoplasmicBy similarityAdd BLAST65

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003372741 – 623Plasma membrane fusion protein PRM1Add BLAST623

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi132N-linked (GlcNAc...)Sequence analysis1
Glycosylationi182N-linked (GlcNAc...)Sequence analysis1
Glycosylationi207N-linked (GlcNAc...)Sequence analysis1
Glycosylationi218N-linked (GlcNAc...)Sequence analysis1
Glycosylationi243N-linked (GlcNAc...)Sequence analysis1
Glycosylationi403N-linked (GlcNAc...)Sequence analysis1
Glycosylationi444N-linked (GlcNAc...)Sequence analysis1
Glycosylationi455N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ59W55.

Expressioni

Inductioni

By pheromones during mating.3 Publications

Family & Domainsi

Sequence similaritiesi

Belongs to the PRM1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ59W55.
OrthoDBiEOG092C1WXV.

Family and domain databases

InterProiIPR026777. PRM1.
[Graphical view]
PANTHERiPTHR31030. PTHR31030. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59W55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRNYLNLPE ILTQVYLNKY AILLILILIK LILLETSILD NLNSVLLDNS
60 70 80 90 100
ICDNGEIQPV LNTVHYMIVD SLQTLEAAGI VSIILTLKVI KQLALFFIEL
110 120 130 140 150
FFGTYICLLN AALKGSTEVA LDASEGVIRA VNATVVSATN DIESALKGLS
160 170 180 190 200
SIINDLVTGF NAIKNMFTGS KSDPTQYQNK INITLGDLKS KIMIPSEVLT
210 220 230 240 250
KLDNFKNSSL YGLSQLGNGT QTIVSTPFEL AIKKLNTMKS SYNFTTGAPS
260 270 280 290 300
PINFREECLK DMSKLKDVQT DLAKLVEKIS KWLFIGLVLA MVGSILYVSY
310 320 330 340 350
IQWRHWRRMD KFINETGIDK EVQFRNQYNI YNNFLIYTIV KRMGIDLNER
360 370 380 390 400
AIWMLSFMFS KISRNVFFFG IMGVVSVVAQ YILLNSVQSS MNNHIKSFDI
410 420 430 440 450
TSNSTSMSAS TIYLRDMNTY IDDTQDKLNQ ELFSGIKEIS VSLNSTIVEF
460 470 480 490 500
LDKLNETLSD IFGSTPLAGP INTVVYCTIG RKLEKVEKGL TWMNDNLNIN
510 520 530 540 550
IPSISRDIED GLSHMTFLQP QSVLARANKI IDLYRKSILL ELYISLGLLG
560 570 580 590 600
VWLFQIFVGS ATLTIRYWNS TRQGNNSYAI SSPHELSEQE KQVYGYPLSH
610 620
PLIDGKDLTT SSSFYPTTEE KSK
Length:623
Mass (Da):70,125
Last modified:April 26, 2005 - v1
Checksum:i2508494BACC066FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000117 Genomic DNA. Translation: EAK94700.1.
AACQ01000116 Genomic DNA. Translation: EAK94741.1.
RefSeqiXP_713802.1. XM_708709.1.
XP_713842.1. XM_708749.1.

Genome annotation databases

EnsemblFungiiEAK94700; EAK94700; CaO19.669.
EAK94741; EAK94741; CaO19.8286.
GeneIDi3644488.
3644549.
KEGGical:CaO19.669.
cal:CaO19.8286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000117 Genomic DNA. Translation: EAK94700.1.
AACQ01000116 Genomic DNA. Translation: EAK94741.1.
RefSeqiXP_713802.1. XM_708709.1.
XP_713842.1. XM_708749.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ59W55.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAK94700; EAK94700; CaO19.669.
EAK94741; EAK94741; CaO19.8286.
GeneIDi3644488.
3644549.
KEGGical:CaO19.669.
cal:CaO19.8286.

Phylogenomic databases

InParanoidiQ59W55.
OrthoDBiEOG092C1WXV.

Family and domain databases

InterProiIPR026777. PRM1.
[Graphical view]
PANTHERiPTHR31030. PTHR31030. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPRM1_CANAL
AccessioniPrimary (citable) accession number: Q59W55
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 26, 2005
Last modified: October 5, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.