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Q59S85

- LPE10_CANAL

UniProt

Q59S85 - LPE10_CANAL

Protein

Mitochondrial inner membrane magnesium transporter LPE10

Gene

LPE10

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis. Modulates the conductance of the MRS2 channel. Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing By similarity.By similarity

    GO - Molecular functioni

    1. magnesium ion transmembrane transporter activity Source: InterPro

    Keywords - Biological processi

    Ion transport, Transport

    Keywords - Ligandi

    Magnesium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mitochondrial inner membrane magnesium transporter LPE10
    Gene namesi
    Name:LPE10
    ORF Names:CaO19.10959, CaO19.3455
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0005011. orf19.3455.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 1919MitochondrionSequence AnalysisAdd
    BLAST
    Chaini20 – 453434Mitochondrial inner membrane magnesium transporter LPE10PRO_0000043236Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0005011.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59S85.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei376 – 39621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei414 – 43421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi400 – 4034YGMN

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi113 – 15846Ser-richAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Transit peptide, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG284534.
    KOiK16075.
    OrthoDBiEOG7SXWCP.

    Family and domain databases

    InterProiIPR026573. MRS2/LPE10.
    [Graphical view]
    PANTHERiPTHR13890. PTHR13890. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q59S85-1 [UniParc]FASTAAdd to Basket

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    MIPIRSSITR ILPNGFSSKL FLRQLNKKSK PNPHKNKNFD SFNEVFIHKT    50
    LLSSINQHND TDYVRCSIFN ANGDMIQHGK EILKSQFIKR YNLTPRDFRK 100
    FNWQRSATGT TTSSSSSSSS AGQTSSGTSK SSSLSSSSSS PHSTISALSL 150
    SNSSLGSSTN VDIVPNITIR RNSILVQLLN IRALINHDQL IIFDNSSSFQ 200
    NSHVSSYTHS QFLKDLSQRL KSTNLDGLPF EFKALEGILI YIVSNLNMEM 250
    KVHNTVLQNI ITGLEDSIDR NKLRYLLIES KKIHQFHRKI TLIKNCLEDL 300
    LENDDELNDL YITEKFNSEG DGQPRQGTNH EEIEMLLENY YQTIDEIVQI 350
    VENLKNQIKT TEDLINVVLD SNRNQLMLLG LKFSTGLLSM GVALYVSALY 400
    GMNLENFIEE IDGGFEVVTV VSTIALIALL LFSVKQLKKV EKVTMTSLND 450
    QRK 453
    Length:453
    Mass (Da):51,123
    Last modified:April 26, 2005 - v1
    Checksum:i42052F3D16AA8E4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000154 Genomic DNA. Translation: EAK93344.1.
    AACQ01000155 Genomic DNA. Translation: EAK93313.1.
    RefSeqiXP_712495.1. XM_707402.1.
    XP_712525.1. XM_707432.1.

    Genome annotation databases

    GeneIDi3645833.
    3645888.
    KEGGical:CaO19.10959.
    cal:CaO19.3455.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000154 Genomic DNA. Translation: EAK93344.1 .
    AACQ01000155 Genomic DNA. Translation: EAK93313.1 .
    RefSeqi XP_712495.1. XM_707402.1.
    XP_712525.1. XM_707432.1.

    3D structure databases

    ProteinModelPortali Q59S85.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0005011.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3645833.
    3645888.
    KEGGi cal:CaO19.10959.
    cal:CaO19.3455.

    Organism-specific databases

    CGDi CAL0005011. orf19.3455.

    Phylogenomic databases

    eggNOGi NOG284534.
    KOi K16075.
    OrthoDBi EOG7SXWCP.

    Family and domain databases

    InterProi IPR026573. MRS2/LPE10.
    [Graphical view ]
    PANTHERi PTHR13890. PTHR13890. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiLPE10_CANAL
    AccessioniPrimary (citable) accession number: Q59S85
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 6, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3