Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q59S72

- ALG11_CANAL

UniProt

Q59S72 - ALG11_CANAL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

Gene

ALG11

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).By similarity

Catalytic activityi

2 GDP-alpha-D-mannose + D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP + D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol.

Pathwayi

GO - Molecular functioni

  1. GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein glycosylation Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00378.

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC:2.4.1.131)
Alternative name(s):
Alpha-1,2-mannosyltransferase ALG11
Asparagine-linked glycosylation protein 11
Glycolipid 2-alpha-mannosyltransferase
Gene namesi
Name:ALG11
ORF Names:CaO19.10972, CaO19.3468
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0005040. ALG11.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 609609GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferasePRO_0000080273Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi307 – 3071N-linked (GlcNAc...)Sequence Analysis
Glycosylationi384 – 3841N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0005040.

Structurei

3D structure databases

ProteinModelPortaliQ59S72.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei2 – 2221HelicalSequence AnalysisAdd
BLAST
Transmembranei196 – 21621HelicalSequence AnalysisAdd
BLAST
Transmembranei231 – 25121HelicalSequence AnalysisAdd
BLAST
Transmembranei278 – 29821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase group 1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0438.
InParanoidiQ59S72.
KOiK03844.
OrthoDBiEOG7673KQ.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
[Graphical view]
PfamiPF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59S72-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYLILLVVLA VYVTYKLITT VLPHHLLIPS QNWREKISYV VKYPKPIYLK
60 70 80 90 100
VGTKRSSYRR RLILASENPA FYTNFINNKL KISPNDCENG DGFLNEMSRR
110 120 130 140 150
DIDDPKRRII YGFFHPYANN GGGGERVLWQ AVKATLLADD KNICVIYTTN
160 170 180 190 200
IEAQPLDILN KANKKFQIDG LDHSRVVFIY LRKFNNLIDG NYWKHFTLIG
210 220 230 240 250
QLFGGILLSL EAMYELSPDV WIDTMGLPSS YLLVSLSLKI PILAYTHFPI
260 270 280 290 300
LQEDMFGKLK FQKLKDLWKF NIIKFNDYFA LGKFIYWSIL YYFYVYLGSK
310 320 330 340 350
VNIALANGSW TFNHLSKIWV FNTALGNVLD VLYPPCGTEF LIKQANLNQP
360 370 380 390 400
RSNKLLYLAQ FRPEKRHALL LKEYSNFLSN NFPNVTQITN KFPTLVFAGS
410 420 430 440 450
CRTADDTATL KFLQEQVAKL DLSRFVEFRI DISYDEVVEL LSSCKFGLNA
460 470 480 490 500
MWNEHFGIGV VEYMARGCIP IVHASAGPLL DMIGRNDQQE NCLNNWKTDG
510 520 530 540 550
GFFFKSYDDP DLDPNLQKNT ETGYIKFELF DQFIDYPTFE TLLKELYVND
560 570 580 590 600
PTIIEDSKLL KMRQIDQNRV AEKFSNKAFN KKWIEYINDL NTLEKQYREE

KRTKVEQVY
Length:609
Mass (Da):70,941
Last modified:April 26, 2005 - v1
Checksum:iD640E1C5D0115CC4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000155 Genomic DNA. Translation: EAK93326.1.
AACQ01000154 Genomic DNA. Translation: EAK93357.1.
RefSeqiXP_712508.1. XM_707415.1.
XP_712538.1. XM_707445.1.

Genome annotation databases

GeneIDi3645846.
3645871.
KEGGical:CaO19.10972.
cal:CaO19.3468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000155 Genomic DNA. Translation: EAK93326.1 .
AACQ01000154 Genomic DNA. Translation: EAK93357.1 .
RefSeqi XP_712508.1. XM_707415.1.
XP_712538.1. XM_707445.1.

3D structure databases

ProteinModelPortali Q59S72.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0005040.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3645846.
3645871.
KEGGi cal:CaO19.10972.
cal:CaO19.3468.

Organism-specific databases

CGDi CAL0005040. ALG11.

Phylogenomic databases

eggNOGi COG0438.
InParanoidi Q59S72.
KOi K03844.
OrthoDBi EOG7673KQ.

Enzyme and pathway databases

UniPathwayi UPA00378 .

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
[Graphical view ]
Pfami PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiALG11_CANAL
AccessioniPrimary (citable) accession number: Q59S72
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3