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Q59S43

- MED11_CANAL

UniProt

Q59S43 - MED11_CANAL

Protein

Mediator of RNA polymerase II transcription subunit 11

Gene

MED11

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors By similarity.By similarity

    GO - Molecular functioni

    1. RNA polymerase II transcription cofactor activity Source: InterPro

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mediator of RNA polymerase II transcription subunit 11
    Alternative name(s):
    Mediator complex subunit 11
    Gene namesi
    Name:MED11
    ORF Names:CaJ7.0143, CaO19.6909
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000135. orf19.6909.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. mediator complex Source: InterPro

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 168168Mediator of RNA polymerase II transcription subunit 11PRO_0000304318Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the Mediator complex.By similarity

    Protein-protein interaction databases

    BioGridi1231843. 1 interaction.
    STRINGi5476.CAL0000135.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Mediator complex subunit 11 family.Curated

    Phylogenomic databases

    eggNOGiNOG46016.
    KOiK15132.
    OrthoDBiEOG76TB3R.

    Family and domain databases

    InterProiIPR019404. Mediator_Med11.
    [Graphical view]
    PfamiPF10280. Med11. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q59S43-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSLDNDKTE NFIQERLDSL HEIDCKVVTL LDQFSSIFQS FYTKSKEDFS    50
    QQTSDIYSTL SKVAIDLRKE IKIMDDNIGA YDKNDDNVMI LPISNVDQKN 100
    TKLGRKRLDL ELAELKRLIS DEKQVETLEN ESNNEIQPKT ESDTNQVETN 150
    ENGNDINNKE SEDIEMKE 168
    Length:168
    Mass (Da):19,417
    Last modified:April 26, 2005 - v1
    Checksum:iB74D0F3D474F63AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006852 Genomic DNA. Translation: BAE44649.1.
    AACQ01000156 Genomic DNA. Translation: EAK93298.1.
    RefSeqiXP_712481.1. XM_707388.1.
    XP_888752.1. XM_883659.1.

    Genome annotation databases

    GeneIDi3645910.
    3704154.
    KEGGical:CaO19.6909.
    cal:CaO19_6909.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP006852 Genomic DNA. Translation: BAE44649.1 .
    AACQ01000156 Genomic DNA. Translation: EAK93298.1 .
    RefSeqi XP_712481.1. XM_707388.1.
    XP_888752.1. XM_883659.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 1231843. 1 interaction.
    STRINGi 5476.CAL0000135.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3645910.
    3704154.
    KEGGi cal:CaO19.6909.
    cal:CaO19_6909.

    Organism-specific databases

    CGDi CAL0000135. orf19.6909.

    Phylogenomic databases

    eggNOGi NOG46016.
    KOi K15132.
    OrthoDBi EOG76TB3R.

    Family and domain databases

    InterProi IPR019404. Mediator_Med11.
    [Graphical view ]
    Pfami PF10280. Med11. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome."
      Chibana H., Oka N., Nakayama H., Aoyama T., Magee B.B., Magee P.T., Mikami Y.
      Genetics 170:1525-1537(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiMED11_CANAL
    AccessioniPrimary (citable) accession number: Q59S43
    Secondary accession number(s): Q3MPL1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3