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Q59S06

- NOP58_CANAL

UniProt

Q59S06 - NOP58_CANAL

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Protein

Nucleolar protein 58

Gene

NOP58

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Required for pre-18S rRNA processing. May bind microtubules (By similarity).By similarity

GO - Biological processi

  1. filamentous growth Source: CGD
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 58
Gene namesi
Name:NOP58
ORF Names:CaO19.1199, CaO19.8790
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
  2. small-subunit processome Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 515515Nucleolar protein 58PRO_0000350979Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi1229177. 1 interaction.
STRINGi5476.CAL0002164.

Structurei

3D structure databases

ProteinModelPortaliQ59S06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini283 – 403121NopPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi435 – 4406Poly-Ala

Sequence similaritiesi

Belongs to the NOP5/NOP56 family.Curated
Contains 1 Nop domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG1498.
InParanoidiQ59S06.
KOiK14565.
OrthoDBiEOG7C5MJW.

Family and domain databases

InterProiIPR012974. NOP5_N.
IPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view]
PfamiPF01798. Nop. 1 hit.
PF08156. NOP5NT. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view]
SMARTiSM00931. NOSIC. 1 hit.
[Graphical view]
PROSITEiPS51358. NOP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59S06 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAYVLTETAA GYALLKAADK KIHKSSSLVE DLNTAEKVAE QFKIHRFEKF
60 70 80 90 100
QSAANALEEA NAIIEGKVSE NLQKLLEDAK SDKKATLIVS EAKLGNAINK
110 120 130 140 150
LGLNFQVVSD AASLDLQRAI KQFLPELLPG LDDSALKQMS LGLAHSMGRH
160 170 180 190 200
KLKFSADKVD TMIIQAIALL DDLDKELNTY AMRCKEWYGW HFPELAKMIT
210 220 230 240 250
DSVAYARIIL TMGVRSNASE TDLSEILPEE VEEQVKAAAE VSMGTEITED
260 270 280 290 300
DLNNIKALAE QIVDFAAYRE QLSNYLSSRM KAIAPNLTAM VGELVGARLI
310 320 330 340 350
AHAGSLTSLA KAPASTVQIL GAEKALFRAL KTKHDTPKYG IIYHASLVGQ
360 370 380 390 400
ASGKNKGRIA RTLAAKAAVS LRYDCFDEER DESDDFGLEN RAKVEGRLSQ
410 420 430 440 450
LEGRDMRTTS KVVREQPKVE ITEARAYNAD ADSTAAAAAA PTADSDDEES
460 470 480 490 500
ETEEVEEKKS KKDKKKDKKE KKDKKKDKKR KRDDDKEDKE SSKKSKKDKK
510
EKKEKKEKKA KKEKK
Length:515
Mass (Da):57,072
Last modified:April 26, 2005 - v1
Checksum:iFE29ED1097D92E8A
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti203 – 2031V → A in allele CaO19.1199.
Natural varianti440 – 4401A → AA in allele CaO19.1199.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000157 Genomic DNA. Translation: EAK93277.1.
AACQ01000161 Genomic DNA. Translation: EAK93126.1.
RefSeqiXP_712316.1. XM_707223.1.
XP_712460.1. XM_707367.1.

Genome annotation databases

GeneIDi3645922.
3646084.
KEGGical:CaO19.1199.
cal:CaO19.8790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000157 Genomic DNA. Translation: EAK93277.1 .
AACQ01000161 Genomic DNA. Translation: EAK93126.1 .
RefSeqi XP_712316.1. XM_707223.1.
XP_712460.1. XM_707367.1.

3D structure databases

ProteinModelPortali Q59S06.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 1229177. 1 interaction.
STRINGi 5476.CAL0002164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3645922.
3646084.
KEGGi cal:CaO19.1199.
cal:CaO19.8790.

Phylogenomic databases

eggNOGi COG1498.
InParanoidi Q59S06.
KOi K14565.
OrthoDBi EOG7C5MJW.

Family and domain databases

InterProi IPR012974. NOP5_N.
IPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view ]
Pfami PF01798. Nop. 1 hit.
PF08156. NOP5NT. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view ]
SMARTi SM00931. NOSIC. 1 hit.
[Graphical view ]
PROSITEi PS51358. NOP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiNOP58_CANAL
AccessioniPrimary (citable) accession number: Q59S06
Secondary accession number(s): Q59RK5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3