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Q59S06

- NOP58_CANAL

UniProt

Q59S06 - NOP58_CANAL

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Protein
Nucleolar protein 58
Gene
NOP58, CaO19.1199, CaO19.8790
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Required for pre-18S rRNA processing. May bind microtubules By similarity.

GO - Biological processi

  1. filamentous growth Source: CGD
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 58
Gene namesi
Name:NOP58
ORF Names:CaO19.1199, CaO19.8790
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolus Source: UniProtKB-SubCell
  2. small-subunit processome Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 515515Nucleolar protein 58
PRO_0000350979Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi1229177. 1 interaction.
STRINGi5476.CAL0002164.

Structurei

3D structure databases

ProteinModelPortaliQ59S06.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini283 – 403121Nop
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi435 – 4406Poly-Ala

Sequence similaritiesi

Belongs to the NOP5/NOP56 family.
Contains 1 Nop domain.

Phylogenomic databases

eggNOGiCOG1498.
KOiK14565.
OrthoDBiEOG7C5MJW.

Family and domain databases

InterProiIPR012974. NOP5_N.
IPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view]
PfamiPF01798. Nop. 1 hit.
PF08156. NOP5NT. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view]
SMARTiSM00931. NOSIC. 1 hit.
[Graphical view]
PROSITEiPS51358. NOP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59S06-1 [UniParc]FASTAAdd to Basket

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MAYVLTETAA GYALLKAADK KIHKSSSLVE DLNTAEKVAE QFKIHRFEKF    50
QSAANALEEA NAIIEGKVSE NLQKLLEDAK SDKKATLIVS EAKLGNAINK 100
LGLNFQVVSD AASLDLQRAI KQFLPELLPG LDDSALKQMS LGLAHSMGRH 150
KLKFSADKVD TMIIQAIALL DDLDKELNTY AMRCKEWYGW HFPELAKMIT 200
DSVAYARIIL TMGVRSNASE TDLSEILPEE VEEQVKAAAE VSMGTEITED 250
DLNNIKALAE QIVDFAAYRE QLSNYLSSRM KAIAPNLTAM VGELVGARLI 300
AHAGSLTSLA KAPASTVQIL GAEKALFRAL KTKHDTPKYG IIYHASLVGQ 350
ASGKNKGRIA RTLAAKAAVS LRYDCFDEER DESDDFGLEN RAKVEGRLSQ 400
LEGRDMRTTS KVVREQPKVE ITEARAYNAD ADSTAAAAAA PTADSDDEES 450
ETEEVEEKKS KKDKKKDKKE KKDKKKDKKR KRDDDKEDKE SSKKSKKDKK 500
EKKEKKEKKA KKEKK 515
Length:515
Mass (Da):57,072
Last modified:April 26, 2005 - v1
Checksum:iFE29ED1097D92E8A
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti203 – 2031V → A in allele CaO19.1199.
Natural varianti440 – 4401A → AA in allele CaO19.1199.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000157 Genomic DNA. Translation: EAK93277.1.
AACQ01000161 Genomic DNA. Translation: EAK93126.1.
RefSeqiXP_712316.1. XM_707223.1.
XP_712460.1. XM_707367.1.

Genome annotation databases

GeneIDi3645922.
3646084.
KEGGical:CaO19.1199.
cal:CaO19.8790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000157 Genomic DNA. Translation: EAK93277.1 .
AACQ01000161 Genomic DNA. Translation: EAK93126.1 .
RefSeqi XP_712316.1. XM_707223.1.
XP_712460.1. XM_707367.1.

3D structure databases

ProteinModelPortali Q59S06.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 1229177. 1 interaction.
STRINGi 5476.CAL0002164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3645922.
3646084.
KEGGi cal:CaO19.1199.
cal:CaO19.8790.

Phylogenomic databases

eggNOGi COG1498.
KOi K14565.
OrthoDBi EOG7C5MJW.

Family and domain databases

InterProi IPR012974. NOP5_N.
IPR002687. Nop_dom.
IPR012976. NOSIC.
[Graphical view ]
Pfami PF01798. Nop. 1 hit.
PF08156. NOP5NT. 1 hit.
PF08060. NOSIC. 1 hit.
[Graphical view ]
SMARTi SM00931. NOSIC. 1 hit.
[Graphical view ]
PROSITEi PS51358. NOP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiNOP58_CANAL
AccessioniPrimary (citable) accession number: Q59S06
Secondary accession number(s): Q59RK5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi