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Protein

Nucleolar protein 58

Gene

NOP58

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for pre-18S rRNA processing. May bind microtubules (By similarity).By similarity

GO - Biological processi

  • filamentous growth Source: CGD
  • rRNA processing Source: UniProtKB-KW

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 58
Gene namesi
Name:NOP58
Ordered Locus Names:CAALFM_C600370CA
ORF Names:CaO19.1199, CaO19.8790
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 6

Organism-specific databases

CGDiCAL0000190357. NOP5.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003509791 – 516Nucleolar protein 58Add BLAST516

Proteomic databases

PRIDEiQ59S06.

Interactioni

Protein-protein interaction databases

BioGridi1229015. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ59S06.
SMRiQ59S06.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini283 – 403NopPROSITE-ProRule annotationAdd BLAST121

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi435 – 441Poly-Ala7

Sequence similaritiesi

Belongs to the NOP5/NOP56 family.Curated

Phylogenomic databases

InParanoidiQ59S06.
KOiK14565.
OrthoDBiEOG092C3GG0.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR012974. NOP5_N.
IPR002687. Nop_dom.
IPR036070. Nop_dom_sf.
IPR012976. NOSIC.
IPR015943. WD40/YVTN_repeat-like_dom_sf.
PfamiView protein in Pfam
PF01798. Nop. 1 hit.
PF08156. NOP5NT. 1 hit.
SMARTiView protein in SMART
SM00931. NOSIC. 1 hit.
SUPFAMiSSF89124. SSF89124. 1 hit.
PROSITEiView protein in PROSITE
PS51358. NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q59S06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYVLTETAA GYALLKAADK KIHKSSSLVE DLNTAEKVAE QFKIHRFEKF
60 70 80 90 100
QSAANALEEA NAIIEGKVSE NLQKLLEDAK SDKKATLIVS EAKLGNAINK
110 120 130 140 150
LGLNFQVVSD AASLDLQRAI KQFLPELLPG LDDSALKQMS LGLAHSMGRH
160 170 180 190 200
KLKFSADKVD TMIIQAIALL DDLDKELNTY AMRCKEWYGW HFPELAKMIT
210 220 230 240 250
DSAAYARIIL TMGVRSNASE TDLSEILPEE VEEQVKAAAE VSMGTEITED
260 270 280 290 300
DLNNIKALAE QIVDFAAYRE QLSNYLSSRM KAIAPNLTAM VGELVGARLI
310 320 330 340 350
AHAGSLTSLA KAPASTVQIL GAEKALFRAL KTKHDTPKYG IIYHASLVGQ
360 370 380 390 400
ASGKNKGRIA RTLAAKAAVS LRYDCFDEER DESDDFGLEN RAKVEGRLSQ
410 420 430 440 450
LEGRDMRTTS KVVREQPKVE ITEARAYNAD ADSTAAAAAA APTADSDDEE
460 470 480 490 500
SETEEVEEKK SKKDKKKDKK EKKDKKKDKK RKRDDDKEDK ESSKKSKKDK
510
KEKKEKKEKK AKKEKK
Length:516
Mass (Da):57,115
Last modified:March 15, 2017 - v2
Checksum:i74D9B04FC45E510B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017628 Genomic DNA. Translation: AOW29986.1.
RefSeqiXP_712316.1. XM_707223.1.

Genome annotation databases

EnsemblFungiiAOW29986; AOW29986; CAALFM_C600370CA.
GeneIDi3646084.
KEGGical:CAALFM_C600370CA.

Similar proteinsi

Entry informationi

Entry nameiNOP58_CANAL
AccessioniPrimary (citable) accession number: Q59S06
Secondary accession number(s): A0A1D8PPD6, Q59RK5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: March 15, 2017
Last modified: November 22, 2017
This is version 67 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families