Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q59RW5 (Q59RW5_CANAL) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:HXK1 CGD orf19.2154 CGD CAL0005368
Synonyms:NAG5 EMBL EAK93243.1
ORF Names:CaO19.2154 EMBL EAK93243.1
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
   Biological processGlycolysis SAAS SAAS022673
   LigandATP-binding SAAS SAAS022673
Nucleotide-binding
   Molecular functionKinase SAAS SAAS022673
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processN-acetylglucosamine catabolic process

Inferred from mutant phenotype PubMed 11298769PubMed 11705974. Source: CGD

adhesion to host

Inferred from genetic interaction PubMed 11705974. Source: CGD

adhesion to other organism involved in symbiotic interaction

Inferred from mutant phenotype PubMed 17139615. Source: CGD

carbohydrate phosphorylation

Inferred from direct assay PubMed 11298769. Source: GOC

development of symbiont in host

Inferred from mutant phenotype PubMed 17139615. Source: CGD

filamentous growth

Inferred from mutant phenotype PubMed 17139615. Source: CGD

filamentous growth of a population of unicellular organisms

Inferred from mutant phenotype PubMed 17139615PubMed 23341961. Source: CGD

glucosamine catabolic process

Inferred from mutant phenotype PubMed 11705974. Source: CGD

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

growth of symbiont in host

Inferred from mutant phenotype PubMed 11298769. Source: CGD

hyphal growth

Inferred from genetic interaction PubMed 11705974. Source: CGD

pathogenesis

Inferred from mutant phenotype PubMed 11298769. Source: CGD

   Cellular_componentcytosol

Inferred from direct assay PubMed 23341961. Source: CGD

mitochondrion

Inferred from direct assay PubMed 23341961. Source: CGD

nucleus

Inferred from direct assay PubMed 23341961. Source: CGD

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

N-acetylglucosamine kinase activity

Inferred from direct assay PubMed 11298769. Source: CGD

hexokinase activity

Inferred from sequence or structural similarity PubMed 11114181. Source: CGD

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q59RW5 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: C3D42FD735B13DF0

FASTA49354,902
        10         20         30         40         50         60 
MTETSISGLR GPKSMYFMEI VDVSSQESSV LSSIVESFTS AVSASNLGVY SDEVLCDIKS 

        70         80         90        100        110        120 
SLKENSPITM LPNYNVSPTG DEHGQYLVID LGGSTLRIAV VDISKPHPNL SRSERITIVV 

       130        140        150        160        170        180 
EKSWIIGNDF KRIDGEFFKY IGSKINEILM GQNVIDVKSV INTGITWSFP LETTDYNRGK 

       190        200        210        220        230        240 
IKHVSKGYTV GEDIYDKDLK MVLEDTLRQE YGLTLDVQSI LNDSLAVYSA GCFIDSKMKL 

       250        260        270        280        290        300 
AMVLGTGINM CCSLKRSSDI HPSKMLADAT LFNCELSLFG QNLCKDFATK YDIIIDKRFA 

       310        320        330        340        350        360 
GFSHHFKTFM EPDPITKTLF QPHELMTSGR YLPELTRLVV VDLIEAGEIF QNVDHQQMYQ 

       370        380        390        400        410        420 
EYGGFSGELM CFVHENDDYD DIHDKLCKAY GWTTVGLSDI VCLKEVVSCI IKRAAFIVAN 

       430        440        450        460        470        480 
AIIAFFKLLG SDELGGDVTI GYVGSVLNYF HKYRRLIVEY VNNAEEAKGI KVDLKLIENS 

       490 
SIIGAAIGAA YHK 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000158 Genomic DNA. Translation: EAK93243.1.
RefSeqXP_712429.1. XM_707336.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0005368.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3645964.
KEGGcal:CaO19.2154.

Organism-specific databases

CGDCAL0005368. HXK1.

Phylogenomic databases

KOK00844.

Family and domain databases

InterProIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERPTHR19443. PTHR19443. 1 hit.
PfamPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSPR00475. HEXOKINASE.
ProtoNetSearch...

Entry information

Entry nameQ59RW5_CANAL
AccessionPrimary (citable) accession number: Q59RW5
Entry history
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)