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Q59RN6

- CHZ1_CANAL

UniProt

Q59RN6 - CHZ1_CANAL

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Protein

Histone H2A.Z-specific chaperone CHZ1

Gene

CHZ1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.By similarity

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2A.Z-specific chaperone CHZ1
Gene namesi
Name:CHZ1
ORF Names:CaO19.13566, CaO19.6147
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0006032. orf19.6147.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 167167Histone H2A.Z-specific chaperone CHZ1PRO_0000330205Add
BLAST

Interactioni

Subunit structurei

Forms a heterotrimer with H2A.Z-H2B, stabilizing the association of the histone dimer. Also, with a lower affinity, forms a heterotrimer with H2A-H2B (By similarity).By similarity

Protein-protein interaction databases

STRINGi5476.CAL0006032.

Structurei

3D structure databases

ProteinModelPortaliQ59RN6.
SMRiQ59RN6. Positions 99-137.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi4 – 157154Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the CHZ1 family.Curated

Phylogenomic databases

eggNOGiNOG42843.
InParanoidiQ59RN6.
OrthoDBiEOG7X9GMP.

Family and domain databases

InterProiIPR019098. Histone_chaperone_domain_CHZ.
[Graphical view]
PfamiPF09649. CHZ. 1 hit.
[Graphical view]
SMARTiSM01082. CHZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59RN6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDESKPIEE PPIESKPQEE QDTEKESVTN SEESKKRAVE PSTDKKKKRR
60 70 80 90 100
RRNYDEEDKE LEKEEAKEKN AKTENNEEGD DDDEDEDDDY EQGKLEDEEE
110 120 130 140 150
EEDELLEIDE SNIITTGRRT RGKVIDFTKA AEELDKERGV VAEEDEEEEE
160
EEEKENEDDD FKEQVQN
Length:167
Mass (Da):19,694
Last modified:April 26, 2005 - v1
Checksum:i3AC187C49AF8A4FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000160 Genomic DNA. Translation: EAK93165.1.
AACQ01000159 Genomic DNA. Translation: EAK93203.1.
RefSeqiXP_712353.1. XM_707260.1.
XP_712389.1. XM_707296.1.

Genome annotation databases

GeneIDi3646009.
3646031.
KEGGical:CaO19.13566.
cal:CaO19.6147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000160 Genomic DNA. Translation: EAK93165.1 .
AACQ01000159 Genomic DNA. Translation: EAK93203.1 .
RefSeqi XP_712353.1. XM_707260.1.
XP_712389.1. XM_707296.1.

3D structure databases

ProteinModelPortali Q59RN6.
SMRi Q59RN6. Positions 99-137.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0006032.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3646009.
3646031.
KEGGi cal:CaO19.13566.
cal:CaO19.6147.

Organism-specific databases

CGDi CAL0006032. orf19.6147.

Phylogenomic databases

eggNOGi NOG42843.
InParanoidi Q59RN6.
OrthoDBi EOG7X9GMP.

Family and domain databases

InterProi IPR019098. Histone_chaperone_domain_CHZ.
[Graphical view ]
Pfami PF09649. CHZ. 1 hit.
[Graphical view ]
SMARTi SM01082. CHZ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiCHZ1_CANAL
AccessioniPrimary (citable) accession number: Q59RN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3