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Q59RN6 (CHZ1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Histone H2A.Z-specific chaperone CHZ1
Gene names
Name:CHZ1
ORF Names:CaO19.13566, CaO19.6147
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin By similarity.

Subunit structure

Forms a heterotrimer with H2A.Z-H2B, stabilizing the association of the histone dimer. Also, with a lower affinity, forms a heterotrimer with H2A-H2B By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the CHZ1 family.

Ontologies

Keywords
   Cellular componentNucleus
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 167167Histone H2A.Z-specific chaperone CHZ1
PRO_0000330205

Regions

Compositional bias4 – 157154Glu-rich

Sequences

Sequence LengthMass (Da)Tools
Q59RN6 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 3AC187C49AF8A4FB

FASTA16719,694
        10         20         30         40         50         60 
MSDESKPIEE PPIESKPQEE QDTEKESVTN SEESKKRAVE PSTDKKKKRR RRNYDEEDKE 

        70         80         90        100        110        120 
LEKEEAKEKN AKTENNEEGD DDDEDEDDDY EQGKLEDEEE EEDELLEIDE SNIITTGRRT 

       130        140        150        160 
RGKVIDFTKA AEELDKERGV VAEEDEEEEE EEEKENEDDD FKEQVQN 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000160 Genomic DNA. Translation: EAK93165.1.
AACQ01000159 Genomic DNA. Translation: EAK93203.1.
RefSeqXP_712353.1. XM_707260.1.
XP_712389.1. XM_707296.1.

3D structure databases

ProteinModelPortalQ59RN6.
SMRQ59RN6. Positions 99-137.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0006032.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3646009.
3646031.
KEGGcal:CaO19.13566.
cal:CaO19.6147.

Organism-specific databases

CGDCAL0006032. orf19.6147.

Phylogenomic databases

eggNOGNOG42843.
OrthoDBEOG7X9GMP.

Family and domain databases

InterProIPR019098. Histone_chaperone_domain_CHZ.
[Graphical view]
PfamPF09649. CHZ. 1 hit.
[Graphical view]
SMARTSM01082. CHZ. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHZ1_CANAL
AccessionPrimary (citable) accession number: Q59RN6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 26, 2005
Last modified: November 13, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names