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Q59R09 (ATM1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Iron-sulfur clusters transporter ATM1, mitochondrial
Gene names
Name:ATM1
ORF Names:CaO19.1077, CaO19.8678
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length750 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors from the mitochondrion By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. [View classification]

Contains 1 ABC transmembrane type-1 domain.

Contains 1 ABC transporter domain.

Sequence caution

The sequence EAK92868.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 1616Mitochondrion Potential
Chain17 – 750734Iron-sulfur clusters transporter ATM1, mitochondrial
PRO_0000255440

Regions

Topological domain17 – 125109Mitochondrial matrix Potential
Transmembrane126 – 14621Helical; Potential
Topological domain147 – 16519Mitochondrial intermembrane Potential
Transmembrane166 – 18621Helical; Potential
Topological domain187 – 24458Mitochondrial matrix Potential
Transmembrane245 – 26521Helical; Potential
Topological domain266 – 2672Mitochondrial intermembrane Potential
Transmembrane268 – 28821Helical; Potential
Topological domain289 – 34860Mitochondrial matrix Potential
Transmembrane349 – 37123Helical; Potential
Topological domain372 – 750379Mitochondrial intermembrane Potential
Domain125 – 415291ABC transmembrane type-1
Domain466 – 702237ABC transporter
Nucleotide binding499 – 5068ATP Potential
Compositional bias23 – 10381Ser-rich
Compositional bias445 – 46016Asn-rich

Sequences

Sequence LengthMass (Da)Tools
Q59R09 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: A3EE9EA5B9732D37

FASTA75084,132
        10         20         30         40         50         60 
MFIRNVKLIK PSPVRFISPI PFSFPISRSI KISSIRYFTN KSTSNFKSTS SSSSLKSTST 

        70         80         90        100        110        120 
STSTSTSKTT PKTLSKPPPK VKPPIQDNDT TSSGSSSSEN SESFMLKSLF KTIWPKNNLN 

       130        140        150        160        170        180 
FKIRVIIALS LLVGAKILNV QVPFYFKQII DTMNIDWTNE VGVFSTVIGS LILAYGGARF 

       190        200        210        220        230        240 
GAVLFGELRN AIFASVAQSA IRRVAYNTFV KLLNMDLQFH LSRQTGGLTR AIDRGTKGIS 

       250        260        270        280        290        300 
YVLSAMVFHI IPITLEISIV CGILTYNYGA SFAAMTFVTM LAYSIFTIQT TAWRTKFRRQ 

       310        320        330        340        350        360 
ANNADNQAAN VALDSLINYE SVKIFNNELY QASKYDKALM KYQQSSVKIA TSLAFLNSGQ 

       370        380        390        400        410        420 
NFIFTSALTA MMYMGCQGVY TGELTVGDLV LINQWVFQLS VPLNFLGSVY RELKQSLLDM 

       430        440        450        460        470        480 
ENLFQLQNQP IRIKEIPNAP PLKLNNNNNN NNNNNNNNNN SLPGEIRFEN VSFGYHPDRP 

       490        500        510        520        530        540 
ILNNASFTIP AGQKVAIVGP SGSGKSTILR LIFRFYDINQ GRILIDGQDI SKVSLESLRK 

       550        560        570        580        590        600 
LIGIVPQETP LFNDTILENI RYGRLDASDE EIYRVINQVQ LNKLIDDLPD GVQTIVGERG 

       610        620        630        640        650        660 
MMISGGEKQR LAMARLLLKR APITFFDEAT SALDTHTEQA LLKTIRSVFK QQHQTNVSIA 

       670        680        690        700        710        720 
HRLRTIADAD KIIVLNKGQV VEEGTHWQLL NEQPNSLYAQ LWNIQENLDI EKELLQGDEE 

       730        740        750 
EEELTEKLKL DKQELEQEAK LFNSQTFEKK

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AACQ01000168 Genomic DNA. Translation: EAK92894.1.
AACQ01000169 Genomic DNA. Translation: EAK92868.1. Sequence problems.
RefSeqXP_712065.1. XM_706972.1.
XP_712090.1. XM_706997.1.

3D structure databases

HSSPHSSP built from PDB template 2GHI based on UniProtKB Q7RBT4.
ProteinModelPortalQ59R09.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ59R09.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3646284.
3646309.
KEGGcal:CaO19.1077.
cal:CaO19.8678.

Organism-specific databases

CGDCAL0001228. ATM1.

Phylogenomic databases

PhylomeDBQ59R09.

Family and domain databases

InterProIPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017940. ABC_transporter_type1.
IPR001140. ABC_transptr_TM_dom.
IPR011527. ABC_transptrTM_dom_typ1.
IPR003593. ATPase_AAA+_core.
[Graphical view]
KOK05663.
PfamPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF90123. ABC_TM_1. 1 hit.
PROSITEPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATM1_CANAL
AccessionPrimary (citable) accession number: Q59R09
Secondary accession number(s): Q59QY3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: April 26, 2005
Last modified: January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

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