##gff-version 3
Q59Q46	UniProtKB	Chain	1	521	.	.	.	ID=PRO_0000415684;Note=Inosine-5'-monophosphate dehydrogenase	
Q59Q46	UniProtKB	Domain	119	178	.	.	.	Note=CBS 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Domain	182	238	.	.	.	Note=CBS 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Active site	333	333	.	.	.	Note=Thioimidate intermediate;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Active site	435	435	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	276	278	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	326	328	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	328	328	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	330	330	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	331	331	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	333	333	.	.	.	Note=In other chain;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	366	368	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	389	390	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	413	417	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	447	447	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	506	506	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	507	507	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Binding site	508	508	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_03156	
Q59Q46	UniProtKB	Mutagenesis	251	251	.	.	.	Note=In MPA-resistant strain%3B decreases the K(M) values for both substrates. Decreases sensitivity to MPA 4-fold%2C but increases sensitivity to mizoribine monophosphate 40-fold. A->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15665003;Dbxref=PMID:15665003