Q59P11 (HSV2_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SVP1-like protein 2

Gene names

Name:	HSV2
ORF Names:	CaO19.1793, CaO19.9359

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	595 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways By similarity.
Subcellular location	Vacuole membrane; Peripheral membrane protein By similarity. Cytoplasmic vesicle membrane; Peripheral membrane protein By similarity. Note: Vesicular and vacuolar By similarity.
Domain	May contain a beta-propeller domain involved in specific binding to phosphatidylinositol 3,5-bisphosphate (PIP2), leading to the association of the protein to the membrane By similarity.
Sequence similarities	Belongs to the WD repeat SVP1 family. Contains 3 WD repeats.

Ontologies

Keywords
Biological process	Protein transport Transport
Cellular component	Cytoplasmic vesicle Membrane Vacuole
Domain	Repeat WD repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasmic vesicle membrane Inferred from electronic annotation. Source: UniProtKB-SubCell vacuolar membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 595	595	SVP1-like protein 2		PRO_0000051025
Regions
	Repeat	30 – 68	39	WD 1
	Repeat	389 – 429	41	WD 2
	Repeat	434 – 473	40	WD 3
	Compositional bias	256 – 339	84	Thr-rich

Sequences

	Sequence		Length	Mass (Da)
	Q59P11 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: C7A833CF32C322CA	FASTA	595	64,279
	10 20 30 40 50 60 MVLAHSINTN PNTNTNTNNT STTSSTTTIP NDSKILCINF NQDQGCFAIS HEQGFLVYNT 70 80 90 100 110 120 DPIELRVKRN FIVNSHTTSS RSNHSNGSNS NNNHRNNSTG SNGSVSSSGS NNETTLGYKS 130 140 150 160 170 180 THKSASGSGS GSGSGIGHIS MLHRTNYLAL IGGGENPKFP INKLIIWDDL KRKTSLSLEF 190 200 210 220 230 240 DTPVLNVLLS RVRIIVVLID QIIVYGFAAP PKKFQTFNTI NNPLGIADLS VNSQQSNVHL 250 260 270 280 290 300 YNNYSSNSAQ AQVSGTTTTT HYDFSKRKSL SPTNSSNSSS TSLKENGTNL TTYPSPSSTT 310 320 330 340 350 360 SASASVATIT NTPEAATTAN PTTATTTATT TATTTTTTTS AKPLVNGIGS SYQTLAFPGR 370 380 390 400 410 420 SMGQIQIVDV GNNHHSGTNI KPTINIIKAH KSNIRCLCLN RTGTLIASAS ITGTIIRIHS 430 440 450 460 470 480 TRTTALLYEF RRGIDRAIIT SMKFSHDDSK LAVLSDKHTL HVYNIDETQY PNDGGSGGTK 490 500 510 520 530 540 DGGGGGRGSK NRHHLLNGLL PYLPNYFQST WSFCSVNTNK YHTSDLEDNS QQQQQQWVAN 550 560 570 580 590 GTGGGGVDEG VIGWSGNDSI IIIWKLKKIW EKYVIVETEN HQYDLIRSSW KRLDS

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000198 Genomic DNA. Translation: EAK92213.1. AACQ01000197 Genomic DNA. Translation: EAK92230.1.
RefSeq	XP_711441.1. XM_706349.1. XP_711458.1. XM_706366.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3646937. 3646948.
KEGG	cal:CaO19.1793. cal:CaO19.9359.
Organism-specific databases
CGD	CAL0000996. orf19.1793.
Phylogenomic databases
eggNOG	NOG317564.
Family and domain databases
Gene3D	2.130.10.10. 2 hits.
InterPro	IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR017986. WD40_repeat_dom. [Graphical view]
Pfam	PF00400. WD40. 1 hit. [Graphical view]
SMART	SM00320. WD40. 3 hits. [Graphical view]
SUPFAM	SSF50978. WD40_like. 1 hit.
PROSITE	PS00678. WD_REPEATS_1. False negative. PS50082. WD_REPEATS_2. False negative. PS50294. WD_REPEATS_REGION. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HSV2_CANAL

Accession

Primary (citable) accession number: Q59P11

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	April 26, 2005
Last modified:	March 6, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program