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Protein

DNA ligase

Gene

CDC9

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
  4. DNA ligase activity Source: CGD

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
  5. filamentous growth Source: CGD
  6. filamentous growth of a population of unicellular organisms Source: CGD
  7. pathogenesis Source: CGD
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:CDC9Imported
ORF Names:CaO19.6155Imported, orf19.6155Imported
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0006047. orf19.6155.

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0006047.

Structurei

3D structure databases

ProteinModelPortaliQ59LP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
InParanoidiQ59LP7.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q59LP7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFSRLVSYRY PIGVPLKQAN RIMSNKKQQS LARFFGGITP PSGSNSTSPE
60 70 80 90 100
KQQSLTRFFG SSSNNSSPKK ATTEAKQKRE ATPPKSPPRS KKARIETKSD
110 120 130 140 150
ESSSSSSSNG DIEMETEPKL EKNNGSGNDV RNEAEELIKL SESEQAKHSN
160 170 180 190 200
EKLGVKIPYA KLASVFEAIE NESSRLAIIA IISQFFLEVL QQSTIDKLIR
210 220 230 240 250
IVYLCINRLG PDYEPGLELG LGETILIKAI SECYGRETSK IKADYKSTGD
260 270 280 290 300
LGLIAQKSRS LQPTMFKTAP LDVDTVFDNS LKIAKSTGKE SQSKKISIIK
310 320 330 340 350
QMLTACQMKS SEAKFLIRSL QGKLRIGSAE KSIIVGLAQA FVNYENKSNK
360 370 380 390 400
KIDPSKLAEA EEIMKEAFSR VPNYEVVLKT AYQYGIFNLL EHCFVTPGIP
410 420 430 440 450
LKPMLANPTK SIGEVLDRFQ NEEFTCEYKY DGVRAQVHIL SDGSIKVFSR
460 470 480 490 500
NLEDMTQTYP DLISIGKQFA VSGNTISMIL DCEAVAWDRE DHKILPFQKL
510 520 530 540 550
TTRKRKDVNE EDIKVQICLF AFDLLYYDNE SLLPKSLAER RKIMQENLSP
560 570 580 590 600
IEDRFQFATA TNSSSNLEVL QQFLDQSIKD SCEGLMVKML NGSESFYEPS
610 620 630 640 650
KRSRNWLKLK KDYLEGVGDS LDLVVIGAYN GKGKRTGTYG GFLLASYNED
660 670 680 690 700
SGDLETCCKI GTGFSDEDLL NLYNKLHPTE IASPKNYFVY DTNNSNAVPD
710 720 730 740 750
VWFEPSMLFE VLTADLSLSP IYKTGHQEFG KGVSLRFPRF IRVRDDKGIE
760 770
DATSSDRVCE FYQRQAHVNN
Length:770
Mass (Da):86,368
Last modified:April 26, 2005 - v1
Checksum:iE75C18797D8B2B1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000251 Genomic DNA. Translation: EAK91388.1.
RefSeqiXP_710637.1. XM_705545.1.

Genome annotation databases

GeneIDi3647757.
KEGGical:CaO19.6155.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000251 Genomic DNA. Translation: EAK91388.1.
RefSeqiXP_710637.1. XM_705545.1.

3D structure databases

ProteinModelPortaliQ59LP7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5476.CAL0006047.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3647757.
KEGGical:CaO19.6155.

Organism-specific databases

CGDiCAL0006047. orf19.6155.

Phylogenomic databases

eggNOGiCOG1793.
InParanoidiQ59LP7.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876Imported.

Entry informationi

Entry nameiQ59LP7_CANAL
AccessioniPrimary (citable) accession number: Q59LP7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: February 4, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.