Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q59HG3

- Q59HG3_HUMAN

UniProt

Q59HG3 - Q59HG3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Ubiquitously transcribed tetratricopeptide repeat variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. histone demethylase activity (H3-K27 specific) Source: Ensembl
  2. metal ion binding Source: InterPro
  3. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. canonical Wnt signaling pathway Source: Ensembl
  2. heart morphogenesis Source: Ensembl
  3. in utero embryonic development Source: Ensembl
  4. mesodermal cell differentiation Source: Ensembl
  5. multicellular organism growth Source: Ensembl
  6. neural tube closure Source: Ensembl
  7. notochord morphogenesis Source: Ensembl
  8. regulation of gene expression Source: Ensembl
  9. respiratory system process Source: Ensembl
  10. somite rostral/caudal axis specification Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitously transcribed tetratricopeptide repeat variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37262.

PTM / Processingi

Proteomic databases

PRIDEiQ59HG3.

Expressioni

Gene expression databases

BgeeiQ59HG3.
ExpressionAtlasiQ59HG3. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000220834.
HOVERGENiHBG018063.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR14017:SF9. PTHR14017:SF9. 1 hit.
PfamiPF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59HG3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
IRCVSMKSCG VSLATAAAAA AAFGDEEKKM AAGKASGESE EASPSLTAEE
60 70 80 90 100
REALGGLDSR LFGFVRFHED GARTKALLGK AVRCYESLIL KAEGKVESDF
110 120 130 140 150
FCQLGHFNLL LEDYPKALSA YQRYYSLQSD YWKNAAFLYG LGLVYFHYNA
160 170 180 190 200
FQWAIKAFQE VLYVDPSFCR AKEIHLRLGL MFKVNTDYES SLKHFQLALV
210 220 230 240 250
DCNPCTLSNA EIQFHIAHLY ETQRKYHSAK EAYEQLLQTE NLSAQVKATV
260 270 280 290 300
LQQLGWMHHT VDLLGDKATK ESYAIQYLQK SLEADPNSGQ SWYFLGRCYS
310 320 330 340 350
SIGKVQDAFI SYRQSIDKSE ASADTWCSIG VLYQQQNQPM DALQAYICAV
360 370 380 390 400
QLDHGHAAAW MDLGTLYESC NQPQDAIKCY LNATRSKSCS NTSALAARIK
410 420 430 440 450
YLQAQLCNLP QGSLQNKTKL LPSIEEAWSL PIPAELTSRQ GAMNTAQQNT
460 470 480 490 500
SDNWSGGHAV SHPPVQQQAH SWCLTPQKLQ HLEQLRANRN NLNPAQKLML
510 520 530 540 550
EQLESQFVLM QQHQMRPTGV AQVRSTGIPN GPTADSSLPT NSVSGQQPQL
560 570 580 590 600
ALTRVPSVSQ PGVRPACPGQ PLANGPFSAG HVPCSTSRTL GSTDTILIGN
610 620 630 640 650
NHITGSGSNG NVPYLQRNAL TLPHNRTNLT SSAEEPWKNQ LSNSTQGLHK
660 670 680 690 700
GQSSHSAGPN GERPLSSTGP SQHLQAAGSG IQNQNGHPTL PSNSVTQGAA
710 720 730 740 750
LNHLSSHTAT SGGQQGITLT KESKPSGNIL TVPETSRHTG ETPNSTASVE
760 770 780 790 800
GLPNHVHQMT ADAVCSPSHG DSKSPGLLSS DNPQLSALLM GKANNNVGTG
810 820 830 840 850
TCDKVNNIHP AVHTKTDNSV ASSPSSAIST ATPSPKSTEQ TTTNSVTSLN
860 870 880 890 900
SPHSGLHTIN GEGMEESQSP MKTDLLLVNH KPSPQIIPSM SVSIYPSSAE
910 920 930 940 950
VLKACRNLGK NGLSNSSILL DKCPPPRPPS SPYPPLPKDK LNPPTPSIYL
960 970 980 990 1000
ENKRDAFFPP LHQFCTNPNN PVTVIRGLAG ALKLDLGLFS TKTLVEANNE
1010 1020 1030 1040 1050
HMVEVRTQLL QPADENWDPT GTKKIWHCES NRSHTTIAKY AQYQASSFQE
1060 1070 1080 1090 1100
SLREENEKRS HHKDHSDSES TSSDNSGRRR KGPFKTIKFG TNIDLSDDKK
1110 1120 1130 1140 1150
WKLQLHELTK LPAFVRVVSA GNLLSHVGHT ILGMNTVQLY MKVPGSRTPG
1160 1170 1180 1190 1200
HQENNNFCSV NINIGPGDCE WFVVPEGYWG VLNDFCEKNN LNFLMGSWWP
1210 1220 1230 1240 1250
NLEDLYEANV PVYRFIQRPG DLVWINAGTV HWVQAIGWCN NIAWNVGPLT
1260 1270 1280 1290 1300
ACQYKLAVER YEWNKLQSVK SIVPMVHLSW NMARNIKVSD PKLFEMIKYC
1310 1320 1330 1340 1350
LLRTLKQCQT LREALIAAGK EIIWHGRTKE EPAHYCSICE VEVFDLLFVT
1360 1370 1380 1390 1400
NESNSRKTYI VHCQDCARKT SGNLENFVVL EQYKMEDLMQ VYDQFTLAPP

LPSASS
Length:1,406
Mass (Da):154,735
Last modified:April 26, 2005 - v1
Checksum:iECB54A9C1B838DC3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB208795 mRNA. Translation: BAD92032.1.
RefSeqiNP_001278347.1. NM_001291418.1.
NP_066963.2. NM_021140.3.
UniGeneiHs.522616.

Genome annotation databases

GeneIDi7403.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB208795 mRNA. Translation: BAD92032.1 .
RefSeqi NP_001278347.1. NM_001291418.1.
NP_066963.2. NM_021140.3.
UniGenei Hs.522616.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q59HG3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7403.

Organism-specific databases

CTDi 7403.
PharmGKBi PA37262.

Phylogenomic databases

HOGENOMi HOG000220834.
HOVERGENi HBG018063.

Miscellaneous databases

GenomeRNAii 7403.
NextBioi 28980.

Gene expression databases

Bgeei Q59HG3.
ExpressionAtlasi Q59HG3. baseline and differential.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR14017:SF9. PTHR14017:SF9. 1 hit.
Pfami PF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view ]
SMARTi SM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view ]
PROSITEi PS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59HG3_HUMAN
AccessioniPrimary (citable) accession number: Q59HG3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.