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Q59HG3

- Q59HG3_HUMAN

UniProt

Q59HG3 - Q59HG3_HUMAN

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Protein
Submitted name:

Ubiquitously transcribed tetratricopeptide repeat variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. histone demethylase activity (H3-K27 specific) Source: Ensembl
  2. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl

GO - Biological processi

  1. canonical Wnt signaling pathway Source: Ensembl
  2. heart development Source: Ensembl
  3. in utero embryonic development Source: Ensembl
  4. mesodermal cell differentiation Source: Ensembl
  5. neural tube closure Source: Ensembl
  6. notochord morphogenesis Source: Ensembl
  7. respiratory system process Source: Ensembl
  8. somite rostral/caudal axis specification Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitously transcribed tetratricopeptide repeat variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37262.

PTM / Processingi

Proteomic databases

PRIDEiQ59HG3.

Expressioni

Gene expression databases

ArrayExpressiQ59HG3.
BgeeiQ59HG3.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000220834.
HOVERGENiHBG018063.
KOiK11447.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR14017:SF9. PTHR14017:SF9. 1 hit.
PfamiPF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59HG3-1 [UniParc]FASTAAdd to Basket

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IRCVSMKSCG VSLATAAAAA AAFGDEEKKM AAGKASGESE EASPSLTAEE     50
REALGGLDSR LFGFVRFHED GARTKALLGK AVRCYESLIL KAEGKVESDF 100
FCQLGHFNLL LEDYPKALSA YQRYYSLQSD YWKNAAFLYG LGLVYFHYNA 150
FQWAIKAFQE VLYVDPSFCR AKEIHLRLGL MFKVNTDYES SLKHFQLALV 200
DCNPCTLSNA EIQFHIAHLY ETQRKYHSAK EAYEQLLQTE NLSAQVKATV 250
LQQLGWMHHT VDLLGDKATK ESYAIQYLQK SLEADPNSGQ SWYFLGRCYS 300
SIGKVQDAFI SYRQSIDKSE ASADTWCSIG VLYQQQNQPM DALQAYICAV 350
QLDHGHAAAW MDLGTLYESC NQPQDAIKCY LNATRSKSCS NTSALAARIK 400
YLQAQLCNLP QGSLQNKTKL LPSIEEAWSL PIPAELTSRQ GAMNTAQQNT 450
SDNWSGGHAV SHPPVQQQAH SWCLTPQKLQ HLEQLRANRN NLNPAQKLML 500
EQLESQFVLM QQHQMRPTGV AQVRSTGIPN GPTADSSLPT NSVSGQQPQL 550
ALTRVPSVSQ PGVRPACPGQ PLANGPFSAG HVPCSTSRTL GSTDTILIGN 600
NHITGSGSNG NVPYLQRNAL TLPHNRTNLT SSAEEPWKNQ LSNSTQGLHK 650
GQSSHSAGPN GERPLSSTGP SQHLQAAGSG IQNQNGHPTL PSNSVTQGAA 700
LNHLSSHTAT SGGQQGITLT KESKPSGNIL TVPETSRHTG ETPNSTASVE 750
GLPNHVHQMT ADAVCSPSHG DSKSPGLLSS DNPQLSALLM GKANNNVGTG 800
TCDKVNNIHP AVHTKTDNSV ASSPSSAIST ATPSPKSTEQ TTTNSVTSLN 850
SPHSGLHTIN GEGMEESQSP MKTDLLLVNH KPSPQIIPSM SVSIYPSSAE 900
VLKACRNLGK NGLSNSSILL DKCPPPRPPS SPYPPLPKDK LNPPTPSIYL 950
ENKRDAFFPP LHQFCTNPNN PVTVIRGLAG ALKLDLGLFS TKTLVEANNE 1000
HMVEVRTQLL QPADENWDPT GTKKIWHCES NRSHTTIAKY AQYQASSFQE 1050
SLREENEKRS HHKDHSDSES TSSDNSGRRR KGPFKTIKFG TNIDLSDDKK 1100
WKLQLHELTK LPAFVRVVSA GNLLSHVGHT ILGMNTVQLY MKVPGSRTPG 1150
HQENNNFCSV NINIGPGDCE WFVVPEGYWG VLNDFCEKNN LNFLMGSWWP 1200
NLEDLYEANV PVYRFIQRPG DLVWINAGTV HWVQAIGWCN NIAWNVGPLT 1250
ACQYKLAVER YEWNKLQSVK SIVPMVHLSW NMARNIKVSD PKLFEMIKYC 1300
LLRTLKQCQT LREALIAAGK EIIWHGRTKE EPAHYCSICE VEVFDLLFVT 1350
NESNSRKTYI VHCQDCARKT SGNLENFVVL EQYKMEDLMQ VYDQFTLAPP 1400
LPSASS 1406
Length:1,406
Mass (Da):154,735
Last modified:April 26, 2005 - v1
Checksum:iECB54A9C1B838DC3
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB208795 mRNA. Translation: BAD92032.1.
RefSeqiNP_001278347.1. NM_001291418.1.
NP_066963.2. NM_021140.3.
UniGeneiHs.522616.

Genome annotation databases

GeneIDi7403.
KEGGihsa:7403.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB208795 mRNA. Translation: BAD92032.1 .
RefSeqi NP_001278347.1. NM_001291418.1.
NP_066963.2. NM_021140.3.
UniGenei Hs.522616.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q59HG3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7403.
KEGGi hsa:7403.

Organism-specific databases

CTDi 7403.
PharmGKBi PA37262.

Phylogenomic databases

HOGENOMi HOG000220834.
HOVERGENi HBG018063.
KOi K11447.

Miscellaneous databases

GenomeRNAii 7403.
NextBioi 28980.

Gene expression databases

ArrayExpressi Q59HG3.
Bgeei Q59HG3.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR14017:SF9. PTHR14017:SF9. 1 hit.
Pfami PF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view ]
SMARTi SM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view ]
PROSITEi PS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59HG3_HUMAN
AccessioniPrimary (citable) accession number: Q59HG3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: September 3, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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