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Q59HG3

- Q59HG3_HUMAN

UniProt

Q59HG3 - Q59HG3_HUMAN

Protein
Submitted name:

Ubiquitously transcribed tetratricopeptide repeat variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. histone demethylase activity (H3-K27 specific) Source: Ensembl
    2. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl

    GO - Biological processi

    1. canonical Wnt signaling pathway Source: Ensembl
    2. heart development Source: Ensembl
    3. in utero embryonic development Source: Ensembl
    4. mesodermal cell differentiation Source: Ensembl
    5. neural tube closure Source: Ensembl
    6. notochord morphogenesis Source: Ensembl
    7. respiratory system process Source: Ensembl
    8. somite rostral/caudal axis specification Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ubiquitously transcribed tetratricopeptide repeat variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA37262.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ59HG3.

    Expressioni

    Gene expression databases

    ArrayExpressiQ59HG3.
    BgeeiQ59HG3.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000220834.
    HOVERGENiHBG018063.

    Family and domain databases

    Gene3Di1.25.40.10. 1 hit.
    InterProiIPR003347. JmjC_dom.
    IPR029517. KDM6A.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view]
    PANTHERiPTHR14017:SF9. PTHR14017:SF9. 1 hit.
    PfamiPF02373. JmjC. 1 hit.
    PF13181. TPR_8. 1 hit.
    [Graphical view]
    SMARTiSM00558. JmjC. 1 hit.
    SM00028. TPR. 6 hits.
    [Graphical view]
    PROSITEiPS51184. JMJC. 1 hit.
    PS50005. TPR. 7 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59HG3-1 [UniParc]FASTAAdd to Basket

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    IRCVSMKSCG VSLATAAAAA AAFGDEEKKM AAGKASGESE EASPSLTAEE     50
    REALGGLDSR LFGFVRFHED GARTKALLGK AVRCYESLIL KAEGKVESDF 100
    FCQLGHFNLL LEDYPKALSA YQRYYSLQSD YWKNAAFLYG LGLVYFHYNA 150
    FQWAIKAFQE VLYVDPSFCR AKEIHLRLGL MFKVNTDYES SLKHFQLALV 200
    DCNPCTLSNA EIQFHIAHLY ETQRKYHSAK EAYEQLLQTE NLSAQVKATV 250
    LQQLGWMHHT VDLLGDKATK ESYAIQYLQK SLEADPNSGQ SWYFLGRCYS 300
    SIGKVQDAFI SYRQSIDKSE ASADTWCSIG VLYQQQNQPM DALQAYICAV 350
    QLDHGHAAAW MDLGTLYESC NQPQDAIKCY LNATRSKSCS NTSALAARIK 400
    YLQAQLCNLP QGSLQNKTKL LPSIEEAWSL PIPAELTSRQ GAMNTAQQNT 450
    SDNWSGGHAV SHPPVQQQAH SWCLTPQKLQ HLEQLRANRN NLNPAQKLML 500
    EQLESQFVLM QQHQMRPTGV AQVRSTGIPN GPTADSSLPT NSVSGQQPQL 550
    ALTRVPSVSQ PGVRPACPGQ PLANGPFSAG HVPCSTSRTL GSTDTILIGN 600
    NHITGSGSNG NVPYLQRNAL TLPHNRTNLT SSAEEPWKNQ LSNSTQGLHK 650
    GQSSHSAGPN GERPLSSTGP SQHLQAAGSG IQNQNGHPTL PSNSVTQGAA 700
    LNHLSSHTAT SGGQQGITLT KESKPSGNIL TVPETSRHTG ETPNSTASVE 750
    GLPNHVHQMT ADAVCSPSHG DSKSPGLLSS DNPQLSALLM GKANNNVGTG 800
    TCDKVNNIHP AVHTKTDNSV ASSPSSAIST ATPSPKSTEQ TTTNSVTSLN 850
    SPHSGLHTIN GEGMEESQSP MKTDLLLVNH KPSPQIIPSM SVSIYPSSAE 900
    VLKACRNLGK NGLSNSSILL DKCPPPRPPS SPYPPLPKDK LNPPTPSIYL 950
    ENKRDAFFPP LHQFCTNPNN PVTVIRGLAG ALKLDLGLFS TKTLVEANNE 1000
    HMVEVRTQLL QPADENWDPT GTKKIWHCES NRSHTTIAKY AQYQASSFQE 1050
    SLREENEKRS HHKDHSDSES TSSDNSGRRR KGPFKTIKFG TNIDLSDDKK 1100
    WKLQLHELTK LPAFVRVVSA GNLLSHVGHT ILGMNTVQLY MKVPGSRTPG 1150
    HQENNNFCSV NINIGPGDCE WFVVPEGYWG VLNDFCEKNN LNFLMGSWWP 1200
    NLEDLYEANV PVYRFIQRPG DLVWINAGTV HWVQAIGWCN NIAWNVGPLT 1250
    ACQYKLAVER YEWNKLQSVK SIVPMVHLSW NMARNIKVSD PKLFEMIKYC 1300
    LLRTLKQCQT LREALIAAGK EIIWHGRTKE EPAHYCSICE VEVFDLLFVT 1350
    NESNSRKTYI VHCQDCARKT SGNLENFVVL EQYKMEDLMQ VYDQFTLAPP 1400
    LPSASS 1406
    Length:1,406
    Mass (Da):154,735
    Last modified:April 26, 2005 - v1
    Checksum:iECB54A9C1B838DC3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB208795 mRNA. Translation: BAD92032.1.
    RefSeqiNP_001278347.1. NM_001291418.1.
    NP_066963.2. NM_021140.3.
    UniGeneiHs.522616.

    Genome annotation databases

    GeneIDi7403.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB208795 mRNA. Translation: BAD92032.1 .
    RefSeqi NP_001278347.1. NM_001291418.1.
    NP_066963.2. NM_021140.3.
    UniGenei Hs.522616.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q59HG3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 7403.

    Organism-specific databases

    PharmGKBi PA37262.

    Phylogenomic databases

    HOGENOMi HOG000220834.
    HOVERGENi HBG018063.

    Miscellaneous databases

    GenomeRNAii 7403.
    NextBioi 28980.

    Gene expression databases

    ArrayExpressi Q59HG3.
    Bgeei Q59HG3.

    Family and domain databases

    Gene3Di 1.25.40.10. 1 hit.
    InterProi IPR003347. JmjC_dom.
    IPR029517. KDM6A.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view ]
    PANTHERi PTHR14017:SF9. PTHR14017:SF9. 1 hit.
    Pfami PF02373. JmjC. 1 hit.
    PF13181. TPR_8. 1 hit.
    [Graphical view ]
    SMARTi SM00558. JmjC. 1 hit.
    SM00028. TPR. 6 hits.
    [Graphical view ]
    PROSITEi PS51184. JMJC. 1 hit.
    PS50005. TPR. 7 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ59HG3_HUMAN
    AccessioniPrimary (citable) accession number: Q59HG3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.