Q59HG1 (Q59HG1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Chromosome-associated kinesin KIF4A variant EMBL BAD92034.1
Organism	Homo sapiens (Human) EMBL BAD92034.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1235 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the kinesin-like protein family. RuleBase RU000394 Contains 1 kinesin-motor domain. SAAS SAAS019821 RuleBase RU000394

Ontologies

Keywords
Cellular component	Microtubule RuleBase RU000394
Ligand	ATP-binding SAAS SAAS019821 RuleBase RU000394 Nucleotide-binding
Molecular function	Motor protein RuleBase RU000394
Gene Ontology (GO)
Biological process	microtubule-based movement Inferred from electronic annotation. Source: InterPro
Cellular component	microtubule Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW microtubule motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92034.1

Sequences

	Sequence		Length	Mass (Da)
	Q59HG1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: D9D236876A5C3218	FASTA	1,235	140,339
	10 20 30 40 50 60 DRIMKEEVKG IPVRVALRCR PLVPKEISEG CQMCLSFVPG EPQVVVGTDK SFTYDFVFDP 70 80 90 100 110 120 STEQEEVFNT AVAPLIKGVF KGYNATVLAY GQTGSGKTYS MGGAYTAEQE NEPTVGVIPR 130 140 150 160 170 180 VIQLLFKEID KKSDFEFTLK VSYLEIYNEE ILDLLCPSRE KAQINIREDP KEGIKIVGLT 190 200 210 220 230 240 EKTVLVALDT VSCLEQGNNS RTVASTAMNS QSSRSHAIFT ISLEQRKKSD KNSSFRSKLH 250 260 270 280 290 300 LVDLAGSERQ KKTKAEGDRL KEGININRGL LCLGNVISAL GDDKKGGFVP YRDSKLTRLL 310 320 330 340 350 360 QDSLGGNSHT LMIACVSPAD SNLEETLNTL RYADRARKIK NKPIVNIDPQ TAELNHLKQQ 370 380 390 400 410 420 VQQLQVLLLQ AHGGTLPGSI TVEPSENLQS LMEKNQSLVE ENEKLSRGLS EAAGQTAQML 430 440 450 460 470 480 ERIIWTEQAN EKMNAKLEEL RQHAACKLDL QKLVETLEDQ ELKENVEIIC NLQQLITQLS 490 500 510 520 530 540 DETVACMAAA IDTAVEQEAQ VETSPETSRS SDAFTTQHAL RQAQMSKELV ELNKALALKE 550 560 570 580 590 600 ALARKMTQND SQLQPIQYQY QDNIKELELE VINLQKEKEE LVLELQTAKK DANQAKLSER 610 620 630 640 650 660 RRKRLQELEG QIADLKKKLN EQSKLLKLKE STERTVSKLN QEIRMMKNQR VQLMRQMKED 670 680 690 700 710 720 AEKFRQWKQK KDKEVIQLKE RDRKRQYELL KLERNFQKQS NVLRRKTEEA AAANKRLKDA 730 740 750 760 770 780 LQKQREVADK RKETQSRGME GTAARVKNWL GNEIEVMVST EEAKRHLNDL LEDRKILAQD 790 800 810 820 830 840 VAQLKEKKES GENPPPKLRR RTFSLTEVRG QVSESEDSIT KQIESLETEM EFRSAQIADL 850 860 870 880 890 900 QQKLLDAESE DRPKQRWENI ATILEAKCAL KYLIGELVSS KIQVSKLESS LKQSKTSCAD 910 920 930 940 950 960 MQKMLFEERN HFAEIETELQ AELVRMEQQH QEKVLYLLSQ LQQSQMAEKQ LEESVSEKEQ 970 980 990 1000 1010 1020 QLLSTLKCQD EELEKMREVC EQNQQLLREN EIIKQKLTLL QVASRQKHLP KDTLLSPDSS 1030 1040 1050 1060 1070 1080 FEYVPPKPKP SRVKEKFLEQ SMDIEDLKYC SEHSVNEHED GDGDDDEGDD EEWKPTKLVK 1090 1100 1110 1120 1130 1140 VSRKNIQGCS CKGWCGNKQC GCRKQKSDCG VDCCCDPTKC RNRQQGKDSL GTVERTQDSE 1150 1160 1170 1180 1190 1200 GSFKLEDPTE VTPGLSFFNP VCATPNSKIL KEMCDVEQVL SKKTPPAPSP FDLPELKHVA 1210 1220 1230 TEYQENKAPG KKKKRALASN TSFFSGCSPI EEEAH

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92034.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB208797 mRNA. Translation: BAD92034.1.
IPI	IPI00178150.
RefSeq	NP_036442.3. NM_012310.4.
UniGene	Hs.648326.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q59HG1.
Proteomic databases
PRIDE	Q59HG1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	24137.
KEGG	hsa:24137.
Organism-specific databases
CTD	24137.
Phylogenomic databases
HOGENOM	HBG506733.
HOVERGEN	HBG052256.
Gene expression databases
ArrayExpress	Q59HG1.
Family and domain databases
InterPro	IPR019821. Kinesin_motor_CS. IPR001752. Kinesin_motor_dom. [Graphical view]
Gene3D	G3DSA:3.40.850.10. kinesin_motor. 1 hit.
KO	K10395.
Pfam	PF00225. Kinesin. 1 hit. [Graphical view]
PRINTS	PR00380. KINESINHEAVY.
SMART	SM00129. KISc. 1 hit. [Graphical view]
PROSITE	PS00411. KINESIN_MOTOR_DOMAIN1. 1 hit. PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	46801.

Entry information

Entry name

Q59HG1_HUMAN

Accession

Primary (citable) accession number: Q59HG1

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.