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Protein
Submitted name:

Calpastatin isoform a variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Protein family/group databases

MEROPSiI27.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Calpastatin isoform a variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ59HE3.

Expressioni

Gene expression databases

GenevisibleiQ59HE3. HS.

Interactioni

Protein-protein interaction databases

MINTiMINT-5004947.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000082405.
HOVERGENiHBG000183.

Family and domain databases

InterProiIPR026998. Calpastatin.
IPR001259. Prot_inh_calpain.
[Graphical view]
PANTHERiPTHR10077. PTHR10077. 1 hit.
PfamiPF00748. Calpain_inhib. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59HE3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SGHRRRNAAT SNPFFLTNRD QSSAGAGAGH RHVSEKTSES PSKPGEKKGS
60 70 80 90 100
DEKKAASLGS SQSSRTYAGG TASATKVSAS SGATSKSSSM NPTETKAIPV
110 120 130 140 150
SQQMEGPHLP NKKKHKKQAV KTEPEKKSQS TKLSVVHEKK SQEGKPKEHT
160 170 180 190 200
EPKSLPKQAS DTGSNDAHNK KAVSRSAEQQ PSEKSTEPKT KPQDMISAGG
210 220 230 240 250
ESVAGITAIS GKPGDKKKEK KSLTPAVPVE SKPDKPSGKS GMDAALDDLI
260 270 280 290 300
DTLGGPEETE EENTTYTGPE VSDPMSSTYI EELGKREVTI PPKYRELLAK
310 320 330 340 350
PIGPDDAIDA LSSDFTCGSP TAAGKKTEKE ESTEVLKAQS AGTVRSAAPP
360 370 380 390 400
QEKKRKVEKD TMSDQALEAL SASLGTRQAE PELDLRSIKE VDEAKAKEEK
410 420 430 440 450
LEKCGEDDET IPSEYRLKPA TDKDGKPLLP EPEEKPKPRS ESELIDELSE
460 470 480 490 500
DFDRSECKEK PSKPTEKTEE SKAAAPAPVS EAVSRTSMCS IQSAPPEPAT
510 520 530 540 550
LKGTVPDDAV EALADSLGKK EADPEDGKPV MDKVKEKAKE EDREKLGEKE
560 570 580 590 600
ETIPPDYRLE EVKDKDGKPL LPKESKEQLP PMSEDFLLDA LSEDFSGPQN
610 620 630 640 650
ASSLKFEDAK LAAAISEVVS QTPASTTQAG APPRDTSQSD KDLDDALDKL
660 670 680 690 700
SDSLGQRQPD PDENKPMEDK VKEKAKAEHR DKLGERDDTI PPEYRHLLDD
710 720 730 740 750
NGQDKPVKPP TKKSEDSKKP ADDQDPIDAL SGDLDSCPST TETSQNTAKD
760 770 780
KCKKAASSSK APKNGGKAKD SAKTTEETSK PKDD
Length:784
Mass (Da):84,228
Last modified:April 26, 2005 - v1
Checksum:i545694098E6C32CF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208816 mRNA. Translation: BAD92053.1.
RefSeqiNP_001177371.1. NM_001190442.1.
UniGeneiHs.436186.

Genome annotation databases

GeneIDi831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208816 mRNA. Translation: BAD92053.1.
RefSeqiNP_001177371.1. NM_001190442.1.
UniGeneiHs.436186.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-5004947.

Protein family/group databases

MEROPSiI27.001.

Proteomic databases

PRIDEiQ59HE3.

Protocols and materials databases

DNASUi831.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi831.

Organism-specific databases

CTDi831.

Phylogenomic databases

HOGENOMiHOG000082405.
HOVERGENiHBG000183.

Miscellaneous databases

GenomeRNAii831.

Gene expression databases

GenevisibleiQ59HE3. HS.

Family and domain databases

InterProiIPR026998. Calpastatin.
IPR001259. Prot_inh_calpain.
[Graphical view]
PANTHERiPTHR10077. PTHR10077. 1 hit.
PfamiPF00748. Calpain_inhib. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59HE3_HUMAN
AccessioniPrimary (citable) accession number: Q59HE3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 8, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.