Unreviewed, UniProtKB/TrEMBL Q59HC6 (Q59HC6_HUMAN)

Names and origin

Protein names	Submitted name:     DNA cytosine methyltransferase 3 alpha isoform a variant EMBL BAD92070.1
Organism	Homo sapiens (Human) EMBL BAD92070.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	811 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Molecular function	Methyltransferase Transferase
Gene Ontology (GO)
Biological process	DNA methylation Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92070.1

Sequences

	Sequence		Length	Mass (Da)
	Q59HC6-1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: F69CFB26CCEAA4D5	FASTA	811	89,707
	10 20 30 40 50 60 LSPPKTTIIP SPKPSSPPAP RSPSLPPGAQ MPAMPSSGPG DTSSSAAERE EDRKDGEEQE 70 80 90 100 110 120 EPRGKEERQE PSTTARKVGR PGRKRKHPPV ESGDTPKDPA VISKSPSMAQ DSGASELLPN 130 140 150 160 170 180 GDLEKRSEPQ PEEGSPAGGQ KGGAPAEGEG AAETLPEASR AVENGCCTPK EGRGAPAEAG 190 200 210 220 230 240 KEQKETNIES MKMEGSRGRL RGGLGWESSL RQRPMPRLTF QAGDPYYISK RKRDEWLARW 250 260 270 280 290 300 KREAEKKAKV IAGMNAVEEN QGPGESQKVE EASPPAVQQP TDPASPTVAT TPEPVGSDAG 310 320 330 340 350 360 DKNATKAGDD EPEYEDGRGF GIGELVWGKL RGFSWWPGRI VSWWMTGRSR AAEGTRWVMW 370 380 390 400 410 420 FGDGKFSVVC VEKLMPLSSF CSAFHQATYN KQPMYRKAIY EVLQVASSRA GKLFPVCHDS 430 440 450 460 470 480 DESDTAKAVE VQNKPMIEWA LGGFQPSGPK GLEPPEEEKN PYKEVYTDMW VEPEAAAYAP 490 500 510 520 530 540 PPPAKKPRKS TAEKPKVKEI IDERTRERLV YEVRQKCRNI EDICISCGSL NVTLEHPLFV 550 560 570 580 590 600 GGMCQNCKNC FLECAYQYDD DGYQSYCTIC CGGREVLMCG NNNCCRCFCV ECVDLLVGPG 610 620 630 640 650 660 AAQAAIKEDP WNCYMCGHKG TYGLLRRRED WPSRLQMFFA NNHDQEFDPP KVYPPVPAEK 670 680 690 700 710 720 RKPIRVLSLF DGIATGLLVL KDLGIQVDRY IASEVCEDSI TVGMVRHQGK IMYVGDVRSV 730 740 750 760 770 780 TQKHIQEWGP FDLVIGGSPC NDLSIVNPAR KGLYEGTGRL FFEFYRLLHD ARPKEGDDRP 790 800 810 FFWLFENVVA MGVSDKRDIS RFLEVQNSHL Y

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92070.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB208833 mRNA. Translation: BAD92070.1.
UniGene	Hs.515840
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000119772. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:2978. DNMT3A.
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q59HC6.
Gene expression databases
ArrayExpress	Q59HC6.
Family and domain databases
InterPro	IPR001525. C5_DNA_meth. IPR000313. PWWP. [Graphical view]
Pfam	PF00145. DNA_methylase. 1 hit. PF00855. PWWP. 1 hit. [Graphical view]
SMART	SM00293. PWWP. 1 hit. [Graphical view]
PROSITE	PS00094. C5_MTASE_1. 1 hit. PS50812. PWWP. 1 hit. [Graphical view]

Entry information

Entry name

Q59HC6_HUMAN

Accession

Primary (citable) accession number: Q59HC6

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	July 22, 2008
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)