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Protein
Submitted name:

Lymphocyte adaptor protein variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ59H48.

Names & Taxonomyi

Protein namesi
Submitted name:
Lymphocyte adaptor protein variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145148124.

PTM / Processingi

Proteomic databases

PaxDbiQ59H48.
PeptideAtlasiQ59H48.

Expressioni

Gene expression databases

GenevisibleiQ59H48. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000345492.

Structurei

3D structure databases

ProteinModelPortaliQ59H48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini228 – 32699SH2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IFCS. Eukaryota.
ENOG410YMBM. LUCA.
HOVERGENiHBG006707.
KOiK12459.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
IPR030523. SH2B.
IPR030522. SH2B3.
[Graphical view]
PANTHERiPTHR10872. PTHR10872. 1 hit.
PTHR10872:SF1. PTHR10872:SF1. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59H48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HFRRSLRHIF RRRSAGELPA AHTAAAPGTP GEAAETPARP GLAKKFLPWS
60 70 80 90 100
LAREPPPEAL KEAVLRYSLA DEASMDSGAR WQRGRLALRR APGPDGPDRV
110 120 130 140 150
LELFDPPKSS RPKLQAACSS IQEVRRCTRL EMPDNLYTFV LKVKDRTDII
160 170 180 190 200
FEVGDEQQLN SWMAELSECT GRGLESTEAE MHIPSALEPS TSSSPRGSTD
210 220 230 240 250
SLNQGASPGG LLDPACQKTD HFLSCYPWFH GPISRVKAAQ LVQLQGPDAH
260 270 280 290 300
GVFLVRQSET RRGEYVLTFN FQGIAKHLRL SLTERGQCRV QHLHFPSVVD
310 320 330 340 350
MLHHFQRSPI PLECGAACDV RLSSYVVVVS QPPGSCNTVL FPFSLPHWDS
360 370 380 390 400
ESLPHWGSEL GLPHLSSSGC PRGLSPEGLP GRSSPPEQIF HLVPSPEELA
410 420 430
NSLQHLEHEP VNRARDSDYE MDSSSRSHLR AIDNQYTPL
Length:439
Mass (Da):48,574
Last modified:April 26, 2005 - v1
Checksum:i7663AF5531A10B84
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208911 mRNA. Translation: BAD92148.1.
RefSeqiNP_001278353.1. NM_001291424.1.
NP_005466.1. NM_005475.2.
UniGeneiHs.506784.

Genome annotation databases

GeneIDi10019.
KEGGihsa:10019.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208911 mRNA. Translation: BAD92148.1.
RefSeqiNP_001278353.1. NM_001291424.1.
NP_005466.1. NM_005475.2.
UniGeneiHs.506784.

3D structure databases

ProteinModelPortaliQ59H48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000345492.

Proteomic databases

PaxDbiQ59H48.
PeptideAtlasiQ59H48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10019.
KEGGihsa:10019.

Organism-specific databases

CTDi10019.
PharmGKBiPA145148124.

Phylogenomic databases

eggNOGiENOG410IFCS. Eukaryota.
ENOG410YMBM. LUCA.
HOVERGENiHBG006707.
KOiK12459.

Enzyme and pathway databases

SignaLinkiQ59H48.

Miscellaneous databases

GenomeRNAii10019.

Gene expression databases

GenevisibleiQ59H48. HS.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
3.30.505.10. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR000980. SH2.
IPR030523. SH2B.
IPR030522. SH2B3.
[Graphical view]
PANTHERiPTHR10872. PTHR10872. 1 hit.
PTHR10872:SF1. PTHR10872:SF1. 1 hit.
PfamiPF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
SMARTiSM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ59H48_HUMAN
AccessioniPrimary (citable) accession number: Q59H48
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 6, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.