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Protein
Submitted name:

Calcium channel, voltage-dependent, beta 2 subunit isoform 1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium channel, voltage-dependent, beta 2 subunit isoform 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA88.

PTM / Processingi

Proteomic databases

PaxDbiQ59H42.
PeptideAtlasiQ59H42.

Expressioni

Gene expression databases

BgeeiQ59H42.
GenevisibleiQ59H42. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000320025.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini70 – 13162SH3InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains SH3 domain.SAAS annotation

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

eggNOGiKOG3812. Eukaryota.
ENOG410XRDI. LUCA.
HOGENOMiHOG000230979.
HOVERGENiHBG050765.
KOiK04863.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
IPR005444. VDCC_L_b2su.
IPR000584. VDCC_L_bsu.
[Graphical view]
PANTHERiPTHR11824. PTHR11824. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF12052. VGCC_beta4Aa_N. 1 hit.
[Graphical view]
PRINTSiPR01626. LCACHANNELB.
PR01628. LCACHANNELB2.
SMARTiSM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59H42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SHTLTAFCPL FMQCCGLVHR RRVRVSYGSA DSYTSRPSDS DVSLEEDREA
60 70 80 90 100
VRREAERQAQ AQLEKAKTKP VAFAVRTNVS YSAAHEDDVP VPGMAISFEA
110 120 130 140 150
KDFLHVKEKF NNDWWIGRLV KEGCEIGFIP SPVKLENMRL QHEQRAKQGK
160 170 180 190 200
FYSSKSGGNS SSSLGDIVPS SRKSTPPSSA IDIDATGLDA EENDIPANHR
210 220 230 240 250
SPKPSANSVT SPHSKEKRMP FFKKTEHTPP YDVVPSMRPV VLVGPSLKGY
260 270 280 290 300
EVTDMMQKAL FDFLKHRFEG RISITRVTAD ISLAKRSVLN NPSKHAIIER
310 320 330 340 350
SNTRSSLAEV QSEIERIFEL ARTLQLVVLD ADTINHPAQL SKTSLAPIIV
360 370 380 390 400
YVKISSPKVL QRLIKSRGKS QAKHLNVQMV AADKLAQCPP ELFDVILDEN
410 420 430 440 450
QLEDACEHLA DYLEAYWKAT HPPSSSLPNP LLSRTLATSS LPLSPTLASN
460 470 480 490 500
SQGSQGDQRT DRSAPIRSAS QAEEEPSVEP VKKSQHRSSS SAPHHNHRSG
510 520 530 540 550
TSRGLSRQET FDSETQESRD SAYVEPKEDY SHDHVDHYAS HRDHNHRDET
560 570 580 590 600
HGSSDHRHRE SRHRSRDVDR EQDHNECNKQ RSRHKSKDRY CEKDGEVISK
610
KRNEAGEWNR DVYIRQ
Length:616
Mass (Da):69,360
Last modified:April 26, 2005 - v1
Checksum:i372E8F373F7015FB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208917 mRNA. Translation: BAD92154.1.
RefSeqiNP_000715.2. NM_000724.3.
UniGeneiHs.59093.

Genome annotation databases

GeneIDi783.
KEGGihsa:783.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208917 mRNA. Translation: BAD92154.1.
RefSeqiNP_000715.2. NM_000724.3.
UniGeneiHs.59093.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000320025.

Proteomic databases

PaxDbiQ59H42.
PeptideAtlasiQ59H42.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi783.
KEGGihsa:783.

Organism-specific databases

CTDi783.
PharmGKBiPA88.

Phylogenomic databases

eggNOGiKOG3812. Eukaryota.
ENOG410XRDI. LUCA.
HOGENOMiHOG000230979.
HOVERGENiHBG050765.
KOiK04863.

Miscellaneous databases

GenomeRNAii783.

Gene expression databases

BgeeiQ59H42.
GenevisibleiQ59H42. HS.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
IPR005444. VDCC_L_b2su.
IPR000584. VDCC_L_bsu.
[Graphical view]
PANTHERiPTHR11824. PTHR11824. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF12052. VGCC_beta4Aa_N. 1 hit.
[Graphical view]
PRINTSiPR01626. LCACHANNELB.
PR01628. LCACHANNELB2.
SMARTiSM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59H42_HUMAN
AccessioniPrimary (citable) accession number: Q59H42
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 6, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.