Q59H21 (Q59H21_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: ATP-dependent RNA helicase ROK1 isoform a variant EMBL BAD92175.1
Organism	Homo sapiens (Human) EMBL BAD92175.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	512 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000452 EMBL BAD92175.1 Hydrolase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92175.1

Sequences

	Sequence		Length	Mass (Da)
	Q59H21 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: FDF9C79816A7F6D5	FASTA	512	57,757
	10 20 30 40 50 60 DVHDLFRRLG AGAKFDTRRF SADAARFQIG KRKYDFDSSE VLQGLDFFGN KKSVPGVCGA 70 80 90 100 110 120 SQTHQKPQNG EKKEESLTER KREQSKKKRK TMTSEIASQE EGATIQWMSS VEAKIEDKKV 130 140 150 160 170 180 QRESKLTSGK LENLRKEKIN FLRNKHKIHV QGTDLPDPIA TFQQLDQEYK INSRLLQNIL 190 200 210 220 230 240 DAGFQMPTPI QMQAIPVMLH GRELLASAPT GSGKTLAFSI PILMQLKQPA NKGFRALIIS 250 260 270 280 290 300 PTRELASQIH RELIKISEGT GFRIHMIHKA AVAAKKFGPK SSKKFDILVT TPNRLIYLLK 310 320 330 340 350 360 QDPPGIDLAS VEWLVVDESD KLFEDGKTGF RDQLASIFLA CTSHKVRRAM FSATFAYDVE 370 380 390 400 410 420 QWCKLNLDNV ISVSIGARNS AVETVEQELL FVGSETGKLL AMRELVKKGF NPPVLVFVQS 430 440 450 460 470 480 IERAKELFHE LIYEGINVDV IHAERTQQQR DNTVHSFRAG KIWVLICTAL LARGIDFKGV 490 500 510 NLVINYDFPT SSVEYIHRIG ELSFFSFPSV TH

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92175.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB208938 mRNA. Translation: BAD92175.1.
IPI	IPI00032423.
RefSeq	NP_008941.2. NM_007010.3.
UniGene	Hs.590937.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q59H21.
Proteomic databases
PRIDE	Q59H21.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	11056.
KEGG	hsa:11056.
Organism-specific databases
CTD	11056.
Phylogenomic databases
HOVERGEN	HBG051332.
KO	K14779.
Gene expression databases
ArrayExpress	Q59H21.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR014014. RNA_helicase_DEAD_Q_motif. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF00271. Helicase_C. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS51195. Q_MOTIF. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	11056.
NextBio	42007.

Entry information

Entry name

Q59H21_HUMAN

Accession

Primary (citable) accession number: Q59H21

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	September 5, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.