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Protein
Submitted name:

Protocadherin gamma subfamily A, 7 isoform 1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin gamma subfamily A, 7 isoform 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Cell membrane SAAS annotation; Single-pass type I membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei652 – 677HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ59H01.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 94CAInterPro annotationAdd BLAST87
Domaini118 – 203CAInterPro annotationAdd BLAST86
Domaini227 – 308CAInterPro annotationAdd BLAST82
Domaini332 – 413CAInterPro annotationAdd BLAST82
Domaini437 – 523CAInterPro annotationAdd BLAST87
Domaini554 – 632CAInterPro annotationAdd BLAST79

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
HOVERGENiHBG054878.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR032455. Cadherin_C.
IPR031904. Cadherin_CBD.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
PfamiView protein in Pfam
PF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
PF16492. Cadherin_C_2. 1 hit.
PF15974. Cadherin_tail. 1 hit.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 6 hits.
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiView protein in PROSITE
PS00232. CADHERIN_1. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q59H01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ETDKGSFVGD IAKDLGLEPR ELAERGVRII SRGRTQLFAL NQRSGSLVTA
60 70 80 90 100
GRIDREEICA QSARCLVNFN ILMEDKMNLY PIDVEIIDIN DNVPRFLTEE
110 120 130 140 150
INVKIMENTA PGVRFPLSEA GDPDVGTNSL QSYQLSPNRH FSLAVQSGDD
160 170 180 190 200
GTKYPELVLE RVLDREEERV HHLVFTASDG GDPPRSSTAH IQVTVVDVND
210 220 230 240 250
HTPVFSLPQY QVTVPENVPV GTRLLTVHAI DLDEGVNGEV TYSFRKITPK
260 270 280 290 300
LPKMFHLNSL TGEISTLEGL DYEETAFYEM EVQAQDGPGS LTKAKVLITV
310 320 330 340 350
LDVNDNAPEV TMTSLSSSIP EDTPLGTVIA LFYLQDRDSG KNGEVTCTIP
360 370 380 390 400
ENLPFKLEKS IDNYYRLVTT KNLDRETLSL YNITLKATDG GTPPLSRETH
410 420 430 440 450
IFMQVADTND NPPTFPHSSY SVYIAENNPR GASIFLVTAQ DHDSEDNAQI
460 470 480 490 500
TYSLAEDTIQ GAPVSSYVSI NSDTGVLYAL QSFDYEQLRE LQLRVTAHDS
510 520 530 540 550
GDPPLSSNMS LSLFVLDQND NPPEILYPAL PTDGSTGMEL APRSAEPGYL
560 570 580 590 600
VTKVVAVDKD SGQNAWLSYL LLKASEPGLF AVGLYTGEVR TARALLDRDA
610 620 630 640 650
LKQSLVVAVQ DHGQPPLSAT VTLTVAVADS IPEVLADLGS LEPSDGPYNY
660 670 680 690 700
DLTLYLVVAV ATVSCVFLAF VLVLLALRLR RWHKSRLLQA SEGGLANVPT
710 720 730 740 750
SHFVGMDGVQ AFLQTYSHEV SLTADSRKSH LIFPQPNYVD MLISQESCEK
760 770 780 790 800
NDSLLTSVDF QECKENLPSI QQAPPNTDWR FSQAQRPGTS GSQNGDDTGT
810 820 830 840 850
WPNNQFDTEM LQAMILASAS EAADGSSTLG GGAGTMGLSA RYGPQFTLQH
860 870 880 890
VPDYRQNVYI PGSNATLTNA AGKRDGKAPA GGNGNKKKSG KKEKK
Length:895
Mass (Da):97,572
Last modified:April 26, 2005 - v1
Checksum:i9CBD698A3B1CD864
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB208958 mRNA. Translation: BAD92195.1.
UniGeneiHs.368160.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ59H01_HUMAN
AccessioniPrimary (citable) accession number: Q59H01
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: May 10, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.