Q59GY7 (Q59GY7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Signal transducer and activator of transcription 5A variant EMBL BAD92209.1
Organism	Homo sapiens (Human) EMBL BAD92209.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	765 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA nucleus Inferred from direct assay. Source: HPA
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92209.1

Sequences

	Sequence		Length	Mass (Da)
	Q59GY7 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 9C1359E4174275E0	FASTA	765	87,535
	10 20 30 40 50 60 TAMAGWIQAQ QLQGDALRQM QVLYGQHFPI EVRHYLAQWI ESQPWDAIDL DNPQDRAQAT 70 80 90 100 110 120 QLLEGLVQEL QKKAEHQVGE DGFLLKIKLG HYATQLQKTY DRCPLELVRC IRHILYNEQR 130 140 150 160 170 180 LVREANNCSS PAGILVDAMS QKHLQINQTF EELRLVTQDT ENELKKLQQT QEYFIIQYQE 190 200 210 220 230 240 SLRIQAQFAQ LAQLSPQERL SRETALQQKQ VSLEAWLQRE AQTLQQYRVE LAEKHQKTLQ 250 260 270 280 290 300 LLRKQQTIIL DDELIQWKRR QQLAGNGGPP EGSLDVLQSW CEKLAEIIWQ NRQQIRRAEH 310 320 330 340 350 360 LCQQLPIPGP VEEMLAEVNA TITDIISALV TSTFIIEKQP PQVLKTQTKF AATVRLLVGG 370 380 390 400 410 420 KLNVHMNPPQ VKATIISEQQ AKSLLKNENT RNECSGEILN NCCVMEYHQA TGTLSAHFRN 430 440 450 460 470 480 MSLKRIKRAD RRGAESVTEE KFTVLFESQF SVGSNELVFQ VKGRVPFAVP DKVLWPQLCE 490 500 510 520 530 540 ALNMKFKAEV QSNRGLTKEN LVFLAQKLFN NSSSHLEDYS GLSVSWSQFN RENLPGWNYT 550 560 570 580 590 600 FWQWFDGVME VLKKHHKPHW NDGAILGFVN KQQAHDLLIN KPDGTFLLRF SDSEIGGITI 610 620 630 640 650 660 AWKFDSPERN LWNLKPFTTR DFSIRSLADR LGDLSYLIYV FPDRPKDEVF SKYYTPVLAK 670 680 690 700 710 720 AVDGYVKPQI KQVVPEFVNA SADAGGSSAT YMDQAPSPAV CPQAPYNMYP QNPDHVLDQD 730 740 750 760 GEFDLDETMD VARHVEELLR RPMDSLDSRL SPPAGLFTSA RGSLS

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92209.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB208972 mRNA. Translation: BAD92209.1.
IPI	IPI00878538.
RefSeq	NP_003143.2. NM_003152.3.
UniGene	Hs.437058.
3D structure databases
ProteinModelPortal	Q59GY7.
SMR	Q59GY7. Positions 140-661.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59GY7.
Proteomic databases
PRIDE	Q59GY7.
Protocols and materials databases
DNASU	6776.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6776.
KEGG	hsa:6776.
UCSC	uc010cyb.2. human.
Organism-specific databases
CTD	6776.
Phylogenomic databases
HOVERGEN	HBG107486.
KO	K11223.
Gene expression databases
ArrayExpress	Q59GY7.
Bgee	Q59GY7.
Family and domain databases
Gene3D	1.10.238.10. 1 hit. 1.10.532.10. 1 hit. 1.20.1050.20. 1 hit. 2.60.40.630. 1 hit. 3.30.505.10. 1 hit.
InterPro	IPR011992. EF-hand-like_dom. IPR008967. p53-like_TF_DNA-bd. IPR000980. SH2. IPR013800. STAT_TF_alpha. IPR015988. STAT_TF_coiled-coil. IPR001217. STAT_TF_core. IPR013801. STAT_TF_DNA-bd. IPR012345. STAT_TF_DNA-bd_sub. IPR013799. STAT_TF_prot_interaction. [Graphical view]
PANTHER	PTHR11801. PTHR11801. 1 hit.
Pfam	PF00017. SH2. 1 hit. PF01017. STAT_alpha. 1 hit. PF02864. STAT_bind. 1 hit. PF02865. STAT_int. 1 hit. [Graphical view]
SMART	SM00252. SH2. 1 hit. SM00964. STAT_int. 1 hit. [Graphical view]
SUPFAM	SSF49417. P53_like_DNA_bnd. 1 hit. SSF47655. STAT. 1 hit. SSF48092. STAT. 1 hit.
PROSITE	PS50001. SH2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	6776.
NextBio	26450.

Entry information

Entry name

Q59GY7_HUMAN

Accession

Primary (citable) accession number: Q59GY7

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	March 6, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.