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Q59GL6

- Q59GL6_HUMAN

UniProt

Q59GL6 - Q59GL6_HUMAN

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Protein
Submitted name:

Mitogen-activated protein kinase kinase kinase 5 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ59GL6.

Names & Taxonomyi

Protein namesi
Submitted name:
Mitogen-activated protein kinase kinase kinase 5 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ59GL6.

PTM databases

PhosphoSiteiQ59GL6.

Structurei

3D structure databases

ProteinModelPortaliQ59GL6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000293286.
HOVERGENiHBG006305.

Family and domain databases

InterProiIPR025136. DUF4071.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR013761. SAM/pointed.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF13281. DUF4071. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59GL6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TLQRASGAAT EAPRRSEPPP GSGVPSGERA PERRRRRGGE GAARDGSCLA
60 70 80 90 100
RRARSSPELW LARRCGWAGD AAAVAARPGE MSTEADEGIT FSVPPFAPSG
110 120 130 140 150
FCTIPEGGIC RRGGAAAVGE GEEHQLPPPP PGSFWNVESA AAPGIGCPAA
160 170 180 190 200
TSSSSATRGR GSSVGGGSRR TTVAYVINEA SQGQLVVAES EALQSLREAC
210 220 230 240 250
ETVGATLETL HFGKLDFGET TVLDRFYNAD IAVVEMSDAF RQPSLFYHLG
260 270 280 290 300
VRESFSMANN IILYCDTNSD SLQSLKEIIC QKNTMCTGNY TFVPYMITPH
310 320 330 340 350
NKVYCCDSSF MKGLTELMQP NFELLLGPIC LPLVDRFIQL LKVAQASSSQ
360 370 380 390 400
YFRESILNDI RKARNLYTGK ELAAELARIR QRVDNIEVLT ADIVINLLLS
410 420 430 440 450
YRDIQDYDSI VKLVETLEKL PTFDLASHHH VKFHYAFALN RRNLPGDRAK
460 470 480 490 500
ALDIMIPMVQ SEGQVASDMY CLVGRIYKDM FLDSNFTDTE SRDHGASWFK
510 520 530 540 550
KAFESEPTLQ SGINYAVLLL AAGHQFESSF ELRKVGVKLS SLLGKKGNLE
560 570 580 590 600
KLQSYWEVGF FLGASVLAND HMRVIQASEK LFKLKTPAWY LKSIVETILI
610 620 630 640 650
YKHFVKLTTE QPVAKQELVD FWMDFLVEAT KTDVTVVRFP VLILEPTKIY
660 670 680 690 700
QPSYLSINNE VEEKTISIWH VLPDDKKGIH EWNFSASSVR GVSISKFEER
710 720 730 740 750
CCFLYVLHNS DDFQIYFCTE PDCKKFFEMV NTITEEKGRS TEEGDCESDL
760 770 780 790 800
LEYDYEYDEN GDRVVLGKGT YGIVYAGRDL SNQVRIAIKE IPERDSRYSQ
810 820 830 840 850
PLHEEIALHK HLKHKNIVQY LGSFSENGFI KIFMEQVPGG SLSALLRSKW
860 870 880 890 900
GPLKDNEQTI GFYTKQILEG LKYLHDNQIV HRDIKGDNVL INTYSGVLKI
910 920 930 940 950
SDFGTSKRLA GINPCTETFT GTLQYMAPEI IDKGPRGYGK AADIWSLGCT
960 970 980 990 1000
IIEMATGKPP FYELGEPQAA MFKVGMFKVH PEIPESMSAE AKAFILKCFE
1010 1020 1030 1040 1050
PDPDKRACAN DLLVDEFLKV SSKKKKTQPK LSALSAGSNE YLRSISLPVP
1060 1070 1080 1090 1100
VLVEDTSSSS EYGSVSPDDT ELKVDPFSFK TRAKSCGERD VKGIRTLFLG
1110 1120 1130 1140 1150
IPDENFEDHS APPSPEEKDS GFFMLRKDSE RRATLHRILT EDQDKIVRNL
1160 1170 1180 1190 1200
MESLAQGAEE PKLKWEHITT LIASLREFVR STDRKIIATT LSKLKLELDF
1210 1220 1230 1240 1250
DSHGISQVQV VLFGFQDAVN KVLRNHNIKP HWMFALDSII RKAVQTAITI
1260 1270 1280 1290 1300
LVPELRPHFS LASESDTADQ EDLDVEDDHE EQPSNQTVRR PQAVIEDAVA
1310 1320 1330 1340 1350
TSGVSTLSST VSHDSQSAHR SLNVQLGRMK IETNRLLEEL VRKEKELQAL
1360 1370 1380 1390 1400
LHRAIEEKDQ EIKHLKLKSQ PIEIPELPVF HLNSSGTNTE DSELTDWLRV
1410 1420 1430 1440 1450
NGADEDTISR FLAEDYTLLD VLYYVTRDDL KCLRLRGGML CTLWKAIIDF

RNKQT
Length:1,455
Mass (Da):162,958
Last modified:April 26, 2005 - v1
Checksum:iA9C71935AB18A0E0
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209093 mRNA. Translation: BAD92330.1.
UniGeneiHs.186486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209093 mRNA. Translation: BAD92330.1 .
UniGenei Hs.186486.

3D structure databases

ProteinModelPortali Q59GL6.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q59GL6.

Proteomic databases

PRIDEi Q59GL6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000293286.
HOVERGENi HBG006305.

Enzyme and pathway databases

SignaLinki Q59GL6.

Family and domain databases

InterProi IPR025136. DUF4071.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR013761. SAM/pointed.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF13281. DUF4071. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF47769. SSF47769. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59GL6_HUMAN
AccessioniPrimary (citable) accession number: Q59GL6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.