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Q59GL6

- Q59GL6_HUMAN

UniProt

Q59GL6 - Q59GL6_HUMAN

Protein
Submitted name:

Mitogen-activated protein kinase kinase kinase 5 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: InterPro

    Keywords - Molecular functioni

    KinaseSAAS annotationImported, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    SignaLinkiQ59GL6.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Mitogen-activated protein kinase kinase kinase 5 variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ59GL6.

    PTM databases

    PhosphoSiteiQ59GL6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59GL6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains protein kinase domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000293286.
    HOVERGENiHBG006305.

    Family and domain databases

    InterProiIPR025136. DUF4071.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR013761. SAM/pointed.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF13281. DUF4071. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF47769. SSF47769. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59GL6-1 [UniParc]FASTAAdd to Basket

    « Hide

    TLQRASGAAT EAPRRSEPPP GSGVPSGERA PERRRRRGGE GAARDGSCLA     50
    RRARSSPELW LARRCGWAGD AAAVAARPGE MSTEADEGIT FSVPPFAPSG 100
    FCTIPEGGIC RRGGAAAVGE GEEHQLPPPP PGSFWNVESA AAPGIGCPAA 150
    TSSSSATRGR GSSVGGGSRR TTVAYVINEA SQGQLVVAES EALQSLREAC 200
    ETVGATLETL HFGKLDFGET TVLDRFYNAD IAVVEMSDAF RQPSLFYHLG 250
    VRESFSMANN IILYCDTNSD SLQSLKEIIC QKNTMCTGNY TFVPYMITPH 300
    NKVYCCDSSF MKGLTELMQP NFELLLGPIC LPLVDRFIQL LKVAQASSSQ 350
    YFRESILNDI RKARNLYTGK ELAAELARIR QRVDNIEVLT ADIVINLLLS 400
    YRDIQDYDSI VKLVETLEKL PTFDLASHHH VKFHYAFALN RRNLPGDRAK 450
    ALDIMIPMVQ SEGQVASDMY CLVGRIYKDM FLDSNFTDTE SRDHGASWFK 500
    KAFESEPTLQ SGINYAVLLL AAGHQFESSF ELRKVGVKLS SLLGKKGNLE 550
    KLQSYWEVGF FLGASVLAND HMRVIQASEK LFKLKTPAWY LKSIVETILI 600
    YKHFVKLTTE QPVAKQELVD FWMDFLVEAT KTDVTVVRFP VLILEPTKIY 650
    QPSYLSINNE VEEKTISIWH VLPDDKKGIH EWNFSASSVR GVSISKFEER 700
    CCFLYVLHNS DDFQIYFCTE PDCKKFFEMV NTITEEKGRS TEEGDCESDL 750
    LEYDYEYDEN GDRVVLGKGT YGIVYAGRDL SNQVRIAIKE IPERDSRYSQ 800
    PLHEEIALHK HLKHKNIVQY LGSFSENGFI KIFMEQVPGG SLSALLRSKW 850
    GPLKDNEQTI GFYTKQILEG LKYLHDNQIV HRDIKGDNVL INTYSGVLKI 900
    SDFGTSKRLA GINPCTETFT GTLQYMAPEI IDKGPRGYGK AADIWSLGCT 950
    IIEMATGKPP FYELGEPQAA MFKVGMFKVH PEIPESMSAE AKAFILKCFE 1000
    PDPDKRACAN DLLVDEFLKV SSKKKKTQPK LSALSAGSNE YLRSISLPVP 1050
    VLVEDTSSSS EYGSVSPDDT ELKVDPFSFK TRAKSCGERD VKGIRTLFLG 1100
    IPDENFEDHS APPSPEEKDS GFFMLRKDSE RRATLHRILT EDQDKIVRNL 1150
    MESLAQGAEE PKLKWEHITT LIASLREFVR STDRKIIATT LSKLKLELDF 1200
    DSHGISQVQV VLFGFQDAVN KVLRNHNIKP HWMFALDSII RKAVQTAITI 1250
    LVPELRPHFS LASESDTADQ EDLDVEDDHE EQPSNQTVRR PQAVIEDAVA 1300
    TSGVSTLSST VSHDSQSAHR SLNVQLGRMK IETNRLLEEL VRKEKELQAL 1350
    LHRAIEEKDQ EIKHLKLKSQ PIEIPELPVF HLNSSGTNTE DSELTDWLRV 1400
    NGADEDTISR FLAEDYTLLD VLYYVTRDDL KCLRLRGGML CTLWKAIIDF 1450
    RNKQT 1455
    Length:1,455
    Mass (Da):162,958
    Last modified:April 26, 2005 - v1
    Checksum:iA9C71935AB18A0E0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209093 mRNA. Translation: BAD92330.1.
    UniGeneiHs.186486.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209093 mRNA. Translation: BAD92330.1 .
    UniGenei Hs.186486.

    3D structure databases

    ProteinModelPortali Q59GL6.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q59GL6.

    Proteomic databases

    PRIDEi Q59GL6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000293286.
    HOVERGENi HBG006305.

    Enzyme and pathway databases

    SignaLinki Q59GL6.

    Family and domain databases

    InterProi IPR025136. DUF4071.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR013761. SAM/pointed.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF13281. DUF4071. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47769. SSF47769. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ59GL6_HUMAN
    AccessioniPrimary (citable) accession number: Q59GL6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.