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Q59GF2

- Q59GF2_HUMAN

UniProt

Q59GF2 - Q59GF2_HUMAN

Protein
Submitted name:

ADAM15 isoform 6a variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. zinc ion binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    ADAM15 isoform 6a variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Proteomic databases

    PRIDEiQ59GF2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59GF2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 peptidase M12B domain.UniRule annotation
    Contains disintegrin domain.SAAS annotation
    Contains peptidase M12B domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG006978.

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    4.10.70.10. 1 hit.
    InterProiIPR006586. ADAM_Cys-rich.
    IPR001762. Blood-coag_inhib_Disintegrin.
    IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR002870. Peptidase_M12B_N.
    [Graphical view]
    PfamiPF08516. ADAM_CR. 1 hit.
    PF00200. Disintegrin. 1 hit.
    PF01562. Pep_M12B_propep. 1 hit.
    PF01421. Reprolysin. 1 hit.
    [Graphical view]
    SMARTiSM00608. ACR. 1 hit.
    SM00050. DISIN. 1 hit.
    SM00181. EGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF57552. SSF57552. 1 hit.
    PROSITEiPS50215. ADAM_MEPRO. 1 hit.
    PS50214. DISINTEGRIN_2. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS50026. EGF_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59GF2-1 [UniParc]FASTAAdd to Basket

    « Hide

    GHLSPPALLS IPSVLSWGVL GPAGGTEEQQ AESEKAPREP LEPQVLQDDL    50
    PISLKKVLQT SLPEPLRIKL ELDGDSHILE LLQNRELVPG RPTLVWYQPD 100
    GTRVVSEGHT LENCCYQGRV RGYAGSWVSI CTCSGLRGLV VLTPERSYTL 150
    EQGPGDLQGP PIISRIQDLH LPGHTCALSW RESVHTQTPP EHPLGQRHIR 200
    RRRDVVTETK TVELVIVADH SEAQKYRDFQ HLLNRTLEVA LLLDTFFRPL 250
    NVRVALVGLE AWTQRDLVEI SPNPAVTLEN FLHWRRAHLL PRLPHDSAQL 300
    VTGTSFSGPT VGMAIQNSIC SPDFSGGVNM DHSTSILGVA SSIAHELGHS 350
    LGLDHDLPGN SCPCPGPAPA KTCIMEASTD FLPGLNFSNC SRRALEKALL 400
    DGMGSCLFER LPSLPPMAAF CGNMFVEPGE QCDCGFLDDC VDPCCDSLTC 450
    QLRPGAQCAS DGPCCQNCQL RPSGWQCRPT RGDCDLPEFC PGDSSQCPPD 500
    VSLGDGEPCA GGQAVCMHGR CASYAQQCQS LWGPGAQPAA PLCLQTANTR 550
    GNAFGSCGRN PSGSYVSCTP RDAICGQLQC QTGRTQPLLG SIRDLLWETI 600
    DVNGTELNCS WVHLDLGSDV AQPLLTLPGT ACGPGLVCID HRCQRVDLLG 650
    AQECRSKCHG HGVCDSNRHC YCEEGWAPPD CTTQLKATSS LTTGLLLSLL 700
    VLLVLVMLGA SYWYRARLHQ RLCQLKGPTC QYRAAQSGPS ERPGPPQRAL 750
    LARGTKASAL SFPAPPSRPL PPDPVSKRLQ AELADRPNPP TRPLPADPVV 800
    RSPKSQGPAK PPPPRKPLPA DPQGRCPSGD LPGPGAGIPP LVVPSRPAPP 850
    PPTVSSLYL 859
    Length:859
    Mass (Da):92,315
    Last modified:April 26, 2005 - v1
    Checksum:i6C2F1161CAC8D1DA
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209157 mRNA. Translation: BAD92394.1.
    UniGeneiHs.312098.

    Genome annotation databases

    UCSCiuc001fgq.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209157 mRNA. Translation: BAD92394.1 .
    UniGenei Hs.312098.

    3D structure databases

    ProteinModelPortali Q59GF2.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q59GF2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc001fgq.1. human.

    Phylogenomic databases

    HOVERGENi HBG006978.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    4.10.70.10. 1 hit.
    InterProi IPR006586. ADAM_Cys-rich.
    IPR001762. Blood-coag_inhib_Disintegrin.
    IPR000742. EG-like_dom.
    IPR013032. EGF-like_CS.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR002870. Peptidase_M12B_N.
    [Graphical view ]
    Pfami PF08516. ADAM_CR. 1 hit.
    PF00200. Disintegrin. 1 hit.
    PF01562. Pep_M12B_propep. 1 hit.
    PF01421. Reprolysin. 1 hit.
    [Graphical view ]
    SMARTi SM00608. ACR. 1 hit.
    SM00050. DISIN. 1 hit.
    SM00181. EGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57552. SSF57552. 1 hit.
    PROSITEi PS50215. ADAM_MEPRO. 1 hit.
    PS50214. DISINTEGRIN_2. 1 hit.
    PS01186. EGF_2. 1 hit.
    PS50026. EGF_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ59GF2_HUMAN
    AccessioniPrimary (citable) accession number: Q59GF2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.