Q59GB4 (Q59GB4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Dihydropyrimidinase-like 2 variant EMBL BAD92432.1
Organism	Homo sapiens (Human) EMBL BAD92432.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	628 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	pyrimidine nucleobase catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92432.1

Sequences

	Sequence		Length	Mass (Da)
	Q59GB4 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: C8C999B286EE9604	FASTA	628	68,184
	10 20 30 40 50 60 IDFDSLSVGR GSGQVVAQQR DVAHLGPDPQ PPYSRQGRRA GGEPSVESGR KVEIRRASGK 70 80 90 100 110 120 EALQNINDQS DRLLIKGGKI VNDDQSFYAD IYMEDGLIKQ IGENLIVPGG VKTIEAHSRM 130 140 150 160 170 180 VIPGGIDVHT RFQMPDQGMT SADDFFQGTK AALAGGTTMI IDHVVPEPGT SLLAAFDQWR 190 200 210 220 230 240 EWADSKSCCD YSLHVDISEW HKGIQEEMEA LVKDHGVNSF LVYMAFKDRF QLTDCQIYEV 250 260 270 280 290 300 LSVIRDIGAI AQVHAENGDI IAEEQQRILD LGITGPEGHV LSRPEEVEAE AVNRAITIAN 310 320 330 340 350 360 QTNCPLYITK VMSKSSAEVI AQARKKGTVV YGEPITASLG TDGSHYWSKN WAKAAAFVTS 370 380 390 400 410 420 PPLSPDPTTP DFLNSLLSCG DLQVTGSAHC TFNTAQKAVG KDNFTLIPEG TNGTEERMSV 430 440 450 460 470 480 IWDKAVVTGK MDENQFVAVT STNAAKVFNL YPRKGRIAVG SDADLVIWDP DSVKTISAKT 490 500 510 520 530 540 HNSSLEYNIF EGMECRGSPL VVISQGKIVL EDGTLHVTEG SGRYIPRKPF PDFVYKRIKA 550 560 570 580 590 600 RSRLAELRGV PRGLYDGPVC EVSVTPKTVT PASSAKTSPA KQQAPPVRNL HQSGFSLSGA 610 620 QIDDNIPRRT TQRIVAPPGG RANITSLG

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92432.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209195 mRNA. Translation: BAD92432.1.
IPI	IPI00883655.
RefSeq	NP_001184222.1. NM_001197293.2.
UniGene	Hs.730599.
3D structure databases
ProteinModelPortal	Q59GB4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59GB4.
Proteomic databases
PRIDE	Q59GB4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1808.
KEGG	hsa:1808.
UCSC	uc003xfa.3. human.
Organism-specific databases
CTD	1808.
Phylogenomic databases
HOGENOM	HOG000219145.
HOVERGEN	HBG000806.
KO	K07528.
Gene expression databases
ArrayExpress	Q59GB4.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR011778. Hydantoinase/dihydroPyrase. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 2 hits.
TIGRFAMs	TIGR02033. D-hydantoinase. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	1808.
NextBio	7369.

Entry information

Entry name

Q59GB4_HUMAN

Accession

Primary (citable) accession number: Q59GB4

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	October 3, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.