Q59G42 (Q59G42_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Eukaryotic translation initiation factor 4 gamma, 2 variant EMBL BAD92504.1
Organism	Homo sapiens (Human) EMBL BAD92504.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	940 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Initiation factor EMBL BAD92504.1
Gene Ontology (GO)
Biological_process	RNA metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92504.1

Sequences

	Sequence		Length	Mass (Da)
	Q59G42 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 56DB1027B537D9FD	FASTA	940	105,828
	10 20 30 40 50 60 VLGEGISFLL SPPLPTPSIN IILLKILRCQ AAKVESAIAE GGASRFSASS GGGGSRGAPQ 70 80 90 100 110 120 HYPKTAGNSE FLGKTPGQNA QKWIPARSTR RDDNSAANNS ANEKERHDAI FRKVRGILNK 130 140 150 160 170 180 LTPEKFDKLC LELLNVGVES KLILKGVILL IVDKALEEPK YSSLYAQLCL RLAEDAPNFD 190 200 210 220 230 240 GPAAEGQPGQ KQSTTFRRLL ISKLQDEFEN RTRNVDVYDK RENPLLPEEE EQRAIAKIKM 250 260 270 280 290 300 LGNIKFIGEL GKLDLIHESI LHKCIKTLLE KKKRVQLKDM GEDLECLCQI MRTVGPRLDH 310 320 330 340 350 360 ERAKSLMDQY FARMCSLMLS KELPARIRFL LQDTVELREH HWVPRKAFLD NGPKTINQIR 370 380 390 400 410 420 QDAVKDLGVF IPAPMAQGMR SDFFLEGPFM PPRMKMDRDP LGGLADMFGQ MPGSGIGTGP 430 440 450 460 470 480 GVIQDRFSPT MGRHRSNQLF NGHGGHIMPP TQSQFGEMGG KFMKSQGLSQ LYHNQSQGLL 490 500 510 520 530 540 SQLQGQSKDM PPRFSKKGQL NADEISLRPA QSFLMNKNQV PKLQPQITMI PPSAQPPRTQ 550 560 570 580 590 600 TPPLGQTPQL GLKTNPPLIQ EKPAKTSKKP PPSKEELLKL TETVVTEYLN SGNANEAVNG 610 620 630 640 650 660 VREMRAPKHF LPEMLSKVII LSLDRSDEDK EKASSLISLL KQEGIATSDN FMQAFLNVLD 670 680 690 700 710 720 QCPKLEVDIP LVKSYLAQFA ARAIISELVS ISELAQPLES GTHFPLFLLC LQQLAKLQDR 730 740 750 760 770 780 EWLTELFQQS KVNMQKMLPE IDQNKDRMLE ILEGKGLSFL FPLLKLEKEL LKQIKLDPSP 790 800 810 820 830 840 QTIYKWIKDN ISPKLHVDKG FVNILMTSFL QYISSEVNPP SDETDSSSAP SKEQLEQEKQ 850 860 870 880 890 900 LLLSFKPVMQ KFLHDHVDLQ VSALYALQVH CYNSNFPKGM LLRFFVHFYD MEIIEEEAFL 910 920 930 940 AWKEDITQEF PGKGKALFQV NQWLTWLETA EEEESEEEAD

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92504.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209267 mRNA. Translation: BAD92504.1.
IPI	IPI00015952.
UniGene	Hs.183684.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q59G42.
Proteomic databases
PRIDE	Q59G42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG052084.
Gene expression databases
ArrayExpress	Q59G42.
Bgee	Q59G42.
Family and domain databases
Gene3D	1.25.40.180. 3 hits.
InterPro	IPR016024. ARM-type_fold. IPR003891. Initiation_fac_eIF4g_MI. IPR016021. MIF4-like_typ_1/2/3. IPR003890. MIF4G-like_typ-3. IPR003307. W2_domain. [Graphical view]
Pfam	PF02847. MA3. 1 hit. PF02854. MIF4G. 1 hit. PF02020. W2. 1 hit. [Graphical view]
SMART	SM00515. eIF5C. 1 hit. SM00544. MA3. 1 hit. SM00543. MIF4G. 1 hit. [Graphical view]
SUPFAM	SSF48371. ARM-type_fold. 3 hits.
PROSITE	PS51366. MI. 1 hit. PS51363. W2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q59G42_HUMAN

Accession

Primary (citable) accession number: Q59G42

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	March 6, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.