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Protein
Submitted name:

Eukaryotic translation initiation factor 4 gamma, 2 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Initiation factorImported

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 4 gamma, 2 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ59G42.

Expressioni

Gene expression databases

BgeeiQ59G42.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000340281.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG052084.

Family and domain databases

Gene3Di1.25.40.180. 3 hits.
InterProiIPR016024. ARM-type_fold.
IPR003891. Initiation_fac_eIF4g_MI.
IPR016021. MIF4-like_typ_1/2/3.
IPR003890. MIF4G-like_typ-3.
IPR003307. W2_domain.
[Graphical view]
PfamiPF02847. MA3. 1 hit.
PF02854. MIF4G. 1 hit.
PF02020. W2. 1 hit.
[Graphical view]
SMARTiSM00515. eIF5C. 1 hit.
SM00544. MA3. 1 hit.
SM00543. MIF4G. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.
PROSITEiPS51366. MI. 1 hit.
PS51363. W2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59G42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VLGEGISFLL SPPLPTPSIN IILLKILRCQ AAKVESAIAE GGASRFSASS
60 70 80 90 100
GGGGSRGAPQ HYPKTAGNSE FLGKTPGQNA QKWIPARSTR RDDNSAANNS
110 120 130 140 150
ANEKERHDAI FRKVRGILNK LTPEKFDKLC LELLNVGVES KLILKGVILL
160 170 180 190 200
IVDKALEEPK YSSLYAQLCL RLAEDAPNFD GPAAEGQPGQ KQSTTFRRLL
210 220 230 240 250
ISKLQDEFEN RTRNVDVYDK RENPLLPEEE EQRAIAKIKM LGNIKFIGEL
260 270 280 290 300
GKLDLIHESI LHKCIKTLLE KKKRVQLKDM GEDLECLCQI MRTVGPRLDH
310 320 330 340 350
ERAKSLMDQY FARMCSLMLS KELPARIRFL LQDTVELREH HWVPRKAFLD
360 370 380 390 400
NGPKTINQIR QDAVKDLGVF IPAPMAQGMR SDFFLEGPFM PPRMKMDRDP
410 420 430 440 450
LGGLADMFGQ MPGSGIGTGP GVIQDRFSPT MGRHRSNQLF NGHGGHIMPP
460 470 480 490 500
TQSQFGEMGG KFMKSQGLSQ LYHNQSQGLL SQLQGQSKDM PPRFSKKGQL
510 520 530 540 550
NADEISLRPA QSFLMNKNQV PKLQPQITMI PPSAQPPRTQ TPPLGQTPQL
560 570 580 590 600
GLKTNPPLIQ EKPAKTSKKP PPSKEELLKL TETVVTEYLN SGNANEAVNG
610 620 630 640 650
VREMRAPKHF LPEMLSKVII LSLDRSDEDK EKASSLISLL KQEGIATSDN
660 670 680 690 700
FMQAFLNVLD QCPKLEVDIP LVKSYLAQFA ARAIISELVS ISELAQPLES
710 720 730 740 750
GTHFPLFLLC LQQLAKLQDR EWLTELFQQS KVNMQKMLPE IDQNKDRMLE
760 770 780 790 800
ILEGKGLSFL FPLLKLEKEL LKQIKLDPSP QTIYKWIKDN ISPKLHVDKG
810 820 830 840 850
FVNILMTSFL QYISSEVNPP SDETDSSSAP SKEQLEQEKQ LLLSFKPVMQ
860 870 880 890 900
KFLHDHVDLQ VSALYALQVH CYNSNFPKGM LLRFFVHFYD MEIIEEEAFL
910 920 930 940
AWKEDITQEF PGKGKALFQV NQWLTWLETA EEEESEEEAD
Length:940
Mass (Da):105,828
Last modified:April 26, 2005 - v1
Checksum:i56DB1027B537D9FD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209267 mRNA. Translation: BAD92504.1.
UniGeneiHs.183684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209267 mRNA. Translation: BAD92504.1.
UniGeneiHs.183684.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000340281.

Proteomic databases

PRIDEiQ59G42.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG052084.

Gene expression databases

BgeeiQ59G42.

Family and domain databases

Gene3Di1.25.40.180. 3 hits.
InterProiIPR016024. ARM-type_fold.
IPR003891. Initiation_fac_eIF4g_MI.
IPR016021. MIF4-like_typ_1/2/3.
IPR003890. MIF4G-like_typ-3.
IPR003307. W2_domain.
[Graphical view]
PfamiPF02847. MA3. 1 hit.
PF02854. MIF4G. 1 hit.
PF02020. W2. 1 hit.
[Graphical view]
SMARTiSM00515. eIF5C. 1 hit.
SM00544. MA3. 1 hit.
SM00543. MIF4G. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 3 hits.
PROSITEiPS51366. MI. 1 hit.
PS51363. W2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59G42_HUMAN
AccessioniPrimary (citable) accession number: Q59G42
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 24, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.