Q59G28 (Q59G28_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Amyloid beta A4 protein-binding, family A, member 2 variant EMBL BAD92518.1
Organism	Homo sapiens (Human) EMBL BAD92518.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	752 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 2 PDZ (DHR) domains. RuleBase RU003354

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92518.1

Sequences

	Sequence		Length	Mass (Da)
	Q59G28 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 7309ABB550871C43	FASTA	752	82,769
	10 20 30 40 50 60 TTAMAHRKLE SVGSGMLDHR VRPGPVPHSQ EPESEDMELP LEGYVPEGLE LAALRPESPA 70 80 90 100 110 120 PEEQECHNHS PDGDSSSDYV NNTSEEEDYD EGLPEEEEGI TYYIRYCPED DSYLEGMDCN 130 140 150 160 170 180 GEEYLAHSAH PVDTDECQEA VEEWTDSAGP HPHGHEAEGS QDYPDGQLPI PEDEPSVLEA 190 200 210 220 230 240 HDQEEDGHYC ASKEGYQDYY PEEANGNTGA SPYRLRRGDG DLEDQEEDID QIVAEIKMSL 250 260 270 280 290 300 SMTSITSASE ASPEHGPEPG PEDSVEACPP IKASCSPSRH EARPKSLNLL PEAKHPGDPQ 310 320 330 340 350 360 RGFKPKTRTP EERPKWPHEQ VCNGLEQPRK QQRSDLNGPV DNNNIPETKK VASFPSFVAV 370 380 390 400 410 420 PGPCEPEDLI DGIIFAANYL GSTQLLSERN PSKNIRMMQA QEAVSRVKRM QKAAKIKKKA 430 440 450 460 470 480 NSEGDAQTLT EVDLFISTQR IKVLNADTQE TMMDHALRTI SYIADIGNIV VLMARRRMPR 490 500 510 520 530 540 SASQDCIETT PGAQEGKKQY KMICHVFESE DAQLIAQSIG QAFSVAYQEF LRANGINPED 550 560 570 580 590 600 LSQKEYSDII NTQEMYNDDL IHFSNSENCK ELQLEKHKGE ILGVVVVESG WGSILPTVIL 610 620 630 640 650 660 ANMMNGGPAA RSGKLSIGDQ IMSINGTSLV GLPLATCQGI IKGLKNQTQV KLNIVSCPPV 670 680 690 700 710 720 TTVLIKRPDL KYQLGFSVQN GIICSLMRGG IAERGGVRVG HRIIEINGQS VVATAHEKIV 730 740 750 QALSNSVGEI HMKTMPAAMF RLLTGQETPL YI

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92518.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209281 mRNA. Translation: BAD92518.1.
IPI	IPI00017817.
RefSeq	NP_001123886.1. NM_001130414.1. NP_005494.2. NM_005503.3.
UniGene	Hs.618112. Hs.721380.
3D structure databases
ProteinModelPortal	Q59G28.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	321.
KEGG	hsa:321.
Organism-specific databases
CTD	321.
PharmGKB	PA24870.
Phylogenomic databases
HOGENOM	HOG000033981.
HOVERGEN	HBG050523.
Family and domain databases
Gene3D	2.30.29.30. 1 hit.
InterPro	IPR001478. PDZ. IPR011993. PH_like_dom. IPR006020. PTyr_interaction_dom. [Graphical view]
Pfam	PF00595. PDZ. 2 hits. PF00640. PID. 1 hit. [Graphical view]
SMART	SM00228. PDZ. 2 hits. SM00462. PTB. 1 hit. [Graphical view]
SUPFAM	SSF50156. PDZ. 2 hits.
PROSITE	PS50106. PDZ. 2 hits. PS01179. PID. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	321.
NextBio	1315.

Entry information

Entry name

Q59G28_HUMAN

Accession

Primary (citable) accession number: Q59G28

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.