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Protein
Submitted name:

Lamina-associated polypeptide 2, isoforms beta/gamma variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Lamina-associated polypeptide 2, isoforms beta/gamma variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei337 – 35822HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiQ59G12.
PaxDbiQ59G12.
PRIDEiQ59G12.

Expressioni

Gene expression databases

BgeeiQ59G12.
GenevisibleiQ59G12. HS.

Interactioni

Protein-protein interaction databases

IntActiQ59G12. 1 interaction.
STRINGi9606.ENSP00000266732.

Structurei

3D structure databases

ProteinModelPortaliQ59G12.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini38 – 8144LEM-likeInterPro annotationAdd
BLAST
Domaini142 – 18645LEMInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IT7C. Eukaryota.
ENOG4111J0N. LUCA.
HOGENOMiHOG000113280.
HOVERGENiHBG000166.

Family and domain databases

Gene3Di1.10.720.40. 2 hits.
InterProiIPR013146. LEM-like_dom.
IPR011015. LEM/LEM-like_dom.
IPR003887. LEM_dom.
[Graphical view]
PfamiPF03020. LEM. 1 hit.
PF08198. Thymopoietin. 1 hit.
[Graphical view]
SMARTiSM00540. LEM. 1 hit.
SM01261. Thymopoietin. 1 hit.
[Graphical view]
SUPFAMiSSF63451. SSF63451. 2 hits.
PROSITEiPS50954. LEM. 1 hit.
PS50955. LEM_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59G12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GSEAAARSPA RSKRAGVSGG GKGCGEGASQ IPEMPEFLED PSVLTKDKLK
60 70 80 90 100
SELVANNVTL PAGEQRKDVY VQLYLQHLTA RNRPPLPAGT NSKGPPDFSS
110 120 130 140 150
DEEREPTPVL GSGAAAAGRS RAAVGRKATK KTDKPRQEDK DDLDVTELTN
160 170 180 190 200
EDLLDQLVKY GVNPGPIVGT TRKLYEKKLL KLREQGTESR SSTPLPTISS
210 220 230 240 250
SAENTRQNGS NDSDRYSDNE EDSKIELKLE KREPLKGRAK TPVTLKQRRV
260 270 280 290 300
EHNQVGEKTE ERRVERDILK EMFPYEASTP TGISASCRRP IKGAAGRPLE
310 320 330 340 350
LSDFRMEESF SSKYVPKYVP LADVKSEKTK KGRSIPVWIK ILLFVVVAVF
360 370
LFLVYQAMET NQVNPFSNFL HVDPRKSN
Length:378
Mass (Da):41,806
Last modified:April 26, 2005 - v1
Checksum:iD73087A941C65F75
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209297 mRNA. Translation: BAD92534.1.
RefSeqiNP_001027454.1. NM_001032283.2.
NP_001027455.1. NM_001032284.2.
UniGeneiHs.11355.

Genome annotation databases

GeneIDi7112.
KEGGihsa:7112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209297 mRNA. Translation: BAD92534.1.
RefSeqiNP_001027454.1. NM_001032283.2.
NP_001027455.1. NM_001032284.2.
UniGeneiHs.11355.

3D structure databases

ProteinModelPortaliQ59G12.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ59G12. 1 interaction.
STRINGi9606.ENSP00000266732.

Proteomic databases

EPDiQ59G12.
PaxDbiQ59G12.
PRIDEiQ59G12.

Protocols and materials databases

DNASUi7112.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7112.
KEGGihsa:7112.

Organism-specific databases

CTDi7112.

Phylogenomic databases

eggNOGiENOG410IT7C. Eukaryota.
ENOG4111J0N. LUCA.
HOGENOMiHOG000113280.
HOVERGENiHBG000166.

Miscellaneous databases

GenomeRNAii7112.

Gene expression databases

BgeeiQ59G12.
GenevisibleiQ59G12. HS.

Family and domain databases

Gene3Di1.10.720.40. 2 hits.
InterProiIPR013146. LEM-like_dom.
IPR011015. LEM/LEM-like_dom.
IPR003887. LEM_dom.
[Graphical view]
PfamiPF03020. LEM. 1 hit.
PF08198. Thymopoietin. 1 hit.
[Graphical view]
SMARTiSM00540. LEM. 1 hit.
SM01261. Thymopoietin. 1 hit.
[Graphical view]
SUPFAMiSSF63451. SSF63451. 2 hits.
PROSITEiPS50954. LEM. 1 hit.
PS50955. LEM_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59G12_HUMAN
AccessioniPrimary (citable) accession number: Q59G12
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 8, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.