Q59FZ8 (Q59FZ8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Nebulette non-muscle isoform variant EMBL BAD92548.1
Organism	Homo sapiens (Human) EMBL BAD92548.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	345 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 LIM zinc-binding domain. RuleBase RU000350 Contains 1 SH3 domain. RuleBase RU003338

Ontologies

Keywords
Domain	LIM domain RuleBase RU000350 SAAS SAAS001781 SH3 domain RuleBase RU003338
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92548.1

Sequences

	Sequence		Length	Mass (Da)
	Q59FZ8 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 9504A817C0214680	FASTA	345	38,697
	10 20 30 40 50 60 RDPAPASPRA RPAPGARPRR PPRALTRGPA PTPYPAPAAR SPPACQEAVR GSPGDVTAAP 70 80 90 100 110 120 GSQQPPPPPP PGTAIMNPQC ARCGKVVYPT EKVNCLDKYW HKGCFHCEVC KMALNMNNYK 130 140 150 160 170 180 GYEKKPYCNA HYPKQSFTTV ADTPENLRLK QQSELQSQVK YKRDFEESKG RGFSIVTDTP 190 200 210 220 230 240 ELQRLKRTQE QISNVKYHED FEKTKGRGFT PVVDDPVIER VRKNTQVVSD AAYKGVHPHI 250 260 270 280 290 300 VEMDRRPGII VAPVLPGAYQ QSHSQGYGYM HQTSVSSMRS MQHSPNLRTY RAMYDYSAQD 310 320 330 340 EDEVSFRDGD YIVNVQPIDD GWMYGTVQRT GRTGMLPANY IEFVN

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92548.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209311 mRNA. Translation: BAD92548.1.
IPI	IPI00418240.
RefSeq	NP_001166955.1. NM_001173484.1. NP_006384.1. NM_006393.2. NP_998734.1. NM_213569.2.
UniGene	Hs.5025.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q59FZ8.
Proteomic databases
PeptideAtlas	Q59FZ8.
PRIDE	Q59FZ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10529.
KEGG	hsa:10529.
Organism-specific databases
CTD	10529.
PharmGKB	PA134981177.
Phylogenomic databases
HOGENOM	HOG000006616.
HOVERGEN	HBG054636.
Gene expression databases
ArrayExpress	Q59FZ8.
Family and domain databases
Gene3D	2.10.110.10. 1 hit.
InterPro	IPR000900. Nebulin_35r-motif. IPR001452. SH3_domain. IPR001781. Znf_LIM. [Graphical view]
Pfam	PF00412. LIM. 1 hit. PF00880. Nebulin. 3 hits. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00452. SH3DOMAIN.
SMART	SM00132. LIM. 1 hit. SM00227. NEBU. 3 hits. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50044. SH3. 1 hit.
PROSITE	PS00478. LIM_DOMAIN_1. 1 hit. PS50023. LIM_DOMAIN_2. 1 hit. PS51216. NEBULIN. 3 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	10529.
NextBio	39946.

Entry information

Entry name

Q59FZ8_HUMAN

Accession

Primary (citable) accession number: Q59FZ8

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.