Q59FY4 (Q59FY4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acetyl-CoA carboxylase 1 Ensembl ENSP00000467820

Submitted name:
Acetyl-Coenzyme A carboxylase alpha isoform 2 variant EMBL BAD92562.1

Gene names

Name:

ACACA Ensembl ENSP00000467820

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAD92562.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	998 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	fatty acid biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro acetyl-CoA carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSP00000467820 EMBL BAD92562.1

Sequences

	Sequence		Length	Mass (Da)
	Q59FY4 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 78A0767D8144A97C	FASTA	998	114,618
	10 20 30 40 50 60 EDDRLAAMFR EFTQQNKATL VDHGIRRLTF LVAQKDFRKQ VNYEVDRRFH REFPKFFTFR 70 80 90 100 110 120 ARDKFEEDRI YRHLEPALAF QLELNRMRNF DLTAIPCANH KMHLYLGAAK VEVGTEVTDY 130 140 150 160 170 180 RFFVRAIIRH SDLVTKEASF EYLQNEGERL LLEAMDELEV AFNNTNVRTD CNHIFLNFVP 190 200 210 220 230 240 TVIMDPSKIE ESVRSMVMRY GSRLWKLRVL QAELKINIRL TPTGKAIPIR LFLTNESGYY 250 260 270 280 290 300 LDISLYKEVT DSRTAQIMFQ AYGDKQGPLH GMLINTPYVT KDLLQSKRFQ AQSLGTTYIY 310 320 330 340 350 360 DIPEMFRQIG MVAWKMTFKS PEYPEGRDII VIGNDITYRI GSFGPQEDLL FLRASELARA 370 380 390 400 410 420 EGIPRIYVSA NSGARIGLAE EIRHMFHVAW VDPEDPYKGY RYLYLTPQDY KRVSALNSVH 430 440 450 460 470 480 CEHVEDEGES RYKITDIIGK EEGIGPENLR GSGMIAGESS LAYNEIITIS LVTCRAIGIG 490 500 510 520 530 540 AYLVRLGQRT IQVENSHLIL TGAGALNKVL GREVYTSNNQ LGGIQIMHNN GVTHCTVCDD 550 560 570 580 590 600 FEGVFTVLHW LSYMPKSVHS SVPLLNSKDP IDRIIEFVPT KTPYDPRWML AGRPHPTQKG 610 620 630 640 650 660 QWLSGFFDYG SFSEIMQPWA QTVVVGRARL GGIPVGVVAV ETRTVELSIP ADPANLDSEA 670 680 690 700 710 720 KIIQQAGQVW FPDSAFKTYQ AIKDFNREGL PLMVFANWRG FSGGMKDMYD QVLKFGAYIV 730 740 750 760 770 780 DGLRECCQPV LVYIPPQAEL RGGSWVVIDS SINPRHMEMY ADRESRGSVL EPEGTVEIKF 790 800 810 820 830 840 RRKDLVKTMR RVDPVYIHLA ERLGTPELST AERKELENKL KEREEFLIPI YHQVAVQFAD 850 860 870 880 890 900 LHDTPGRMQE KGVISDILDW KTSRTFFYWR LRRLLLEDLV KKKIHNANPE LTDGQIQAML 910 920 930 940 950 960 RRWFVEVEGT VKAYVWDNNK DLAEWLEKQL TEEDGVHSVI EENIKCISRD YVLKQIRSLV 970 980 990 QANPEVAMDS IIHMTQHISP TQRAEVIRIL STMDSPST

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92562.1.
[2]	"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C. Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (NOV-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC003103 Genomic DNA. No translation available. AC016482 Genomic DNA. No translation available. AC068400 Genomic DNA. No translation available. AB209325 mRNA. Translation: BAD92562.1.
IPI	IPI01014477.
UniGene	Hs.160556.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q59FY4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000591119; ENSP00000467820; ENSG00000132142.
UCSC	uc010cuy.3. human.
Organism-specific databases
HGNC	HGNC:84. ACACA.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG086472.
Gene expression databases
ArrayExpress	Q59FY4.
Family and domain databases
InterPro	IPR013537. AcCoA_COase_cen. IPR000022. Carboxyl_trans. IPR011763. COA_CT_C. IPR011762. COA_CT_N. [Graphical view]
Pfam	PF08326. ACC_central. 1 hit. PF01039. Carboxyl_trans. 1 hit. [Graphical view]
PROSITE	PS50989. COA_CT_CTER. 1 hit. PS50980. COA_CT_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q59FY4_HUMAN

Accession

Primary (citable) accession number: Q59FY4

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.