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Q59FY4

- Q59FY4_HUMAN

UniProt

Q59FY4 - Q59FY4_HUMAN

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Protein
Submitted name:

Acetyl-CoA carboxylase 1

Gene

ACACA

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. acetyl-CoA carboxylase activity Source: InterPro
  2. ATP binding Source: InterPro

GO - Biological processi

  1. fatty acid biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Acetyl-CoA carboxylase 1Imported
Submitted name:
Acetyl-Coenzyme A carboxylase alpha isoform 2 variantImported
Gene namesi
Name:ACACAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:84. ACACA.

Expressioni

Gene expression databases

ExpressionAtlasiQ59FY4. differential.

Structurei

3D structure databases

ProteinModelPortaliQ59FY4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074703.
HOVERGENiHBG086472.

Family and domain databases

Gene3Di3.90.226.10. 3 hits.
InterProiIPR013537. AcCoA_COase_cen.
IPR000022. Carboxyl_trans.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
[Graphical view]
PfamiPF08326. ACC_central. 1 hit.
PF01039. Carboxyl_trans. 1 hit.
[Graphical view]
SUPFAMiSSF52096. SSF52096. 2 hits.
PROSITEiPS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59FY4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
EDDRLAAMFR EFTQQNKATL VDHGIRRLTF LVAQKDFRKQ VNYEVDRRFH
60 70 80 90 100
REFPKFFTFR ARDKFEEDRI YRHLEPALAF QLELNRMRNF DLTAIPCANH
110 120 130 140 150
KMHLYLGAAK VEVGTEVTDY RFFVRAIIRH SDLVTKEASF EYLQNEGERL
160 170 180 190 200
LLEAMDELEV AFNNTNVRTD CNHIFLNFVP TVIMDPSKIE ESVRSMVMRY
210 220 230 240 250
GSRLWKLRVL QAELKINIRL TPTGKAIPIR LFLTNESGYY LDISLYKEVT
260 270 280 290 300
DSRTAQIMFQ AYGDKQGPLH GMLINTPYVT KDLLQSKRFQ AQSLGTTYIY
310 320 330 340 350
DIPEMFRQIG MVAWKMTFKS PEYPEGRDII VIGNDITYRI GSFGPQEDLL
360 370 380 390 400
FLRASELARA EGIPRIYVSA NSGARIGLAE EIRHMFHVAW VDPEDPYKGY
410 420 430 440 450
RYLYLTPQDY KRVSALNSVH CEHVEDEGES RYKITDIIGK EEGIGPENLR
460 470 480 490 500
GSGMIAGESS LAYNEIITIS LVTCRAIGIG AYLVRLGQRT IQVENSHLIL
510 520 530 540 550
TGAGALNKVL GREVYTSNNQ LGGIQIMHNN GVTHCTVCDD FEGVFTVLHW
560 570 580 590 600
LSYMPKSVHS SVPLLNSKDP IDRIIEFVPT KTPYDPRWML AGRPHPTQKG
610 620 630 640 650
QWLSGFFDYG SFSEIMQPWA QTVVVGRARL GGIPVGVVAV ETRTVELSIP
660 670 680 690 700
ADPANLDSEA KIIQQAGQVW FPDSAFKTYQ AIKDFNREGL PLMVFANWRG
710 720 730 740 750
FSGGMKDMYD QVLKFGAYIV DGLRECCQPV LVYIPPQAEL RGGSWVVIDS
760 770 780 790 800
SINPRHMEMY ADRESRGSVL EPEGTVEIKF RRKDLVKTMR RVDPVYIHLA
810 820 830 840 850
ERLGTPELST AERKELENKL KEREEFLIPI YHQVAVQFAD LHDTPGRMQE
860 870 880 890 900
KGVISDILDW KTSRTFFYWR LRRLLLEDLV KKKIHNANPE LTDGQIQAML
910 920 930 940 950
RRWFVEVEGT VKAYVWDNNK DLAEWLEKQL TEEDGVHSVI EENIKCISRD
960 970 980 990
YVLKQIRSLV QANPEVAMDS IIHMTQHISP TQRAEVIRIL STMDSPST
Length:998
Mass (Da):114,618
Last modified:April 26, 2005 - v1
Checksum:i78A0767D8144A97C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC243628 Genomic DNA. No translation available.
AC243654 Genomic DNA. No translation available.
AC244093 Genomic DNA. No translation available.
AB209325 mRNA. Translation: BAD92562.1.
UniGeneiHs.160556.

Genome annotation databases

EnsembliENST00000619546; ENSP00000483969; ENSG00000278540.
UCSCiuc010cuy.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC243628 Genomic DNA. No translation available.
AC243654 Genomic DNA. No translation available.
AC244093 Genomic DNA. No translation available.
AB209325 mRNA. Translation: BAD92562.1 .
UniGenei Hs.160556.

3D structure databases

ProteinModelPortali Q59FY4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000619546 ; ENSP00000483969 ; ENSG00000278540 .
UCSCi uc010cuy.3. human.

Organism-specific databases

HGNCi HGNC:84. ACACA.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00550000074703.
HOVERGENi HBG086472.

Gene expression databases

ExpressionAtlasi Q59FY4. differential.

Family and domain databases

Gene3Di 3.90.226.10. 3 hits.
InterProi IPR013537. AcCoA_COase_cen.
IPR000022. Carboxyl_trans.
IPR029045. ClpP/crotonase-like_dom.
IPR011763. COA_CT_C.
IPR011762. COA_CT_N.
[Graphical view ]
Pfami PF08326. ACC_central. 1 hit.
PF01039. Carboxyl_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF52096. SSF52096. 2 hits.
PROSITEi PS50989. COA_CT_CTER. 1 hit.
PS50980. COA_CT_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ59FY4_HUMAN
AccessioniPrimary (citable) accession number: Q59FY4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3