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Q59FY1

- Q59FY1_HUMAN

UniProt

Q59FY1 - Q59FY1_HUMAN

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Protein
Submitted name:

Synapse-associated protein 102 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. establishment of planar polarity Source: Ensembl
  2. establishment or maintenance of epithelial cell apical/basal polarity Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Synapse-associated protein 102 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: Ensembl
  2. cytoplasm Source: Ensembl
  3. dendritic shaft Source: Ensembl
  4. growth cone Source: Ensembl
  5. neuronal cell body Source: Ensembl
  6. synapse Source: Ensembl
  7. tight junction Source: Ensembl
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA164741439.

PTM / Processingi

Proteomic databases

PRIDEiQ59FY1.

Expressioni

Gene expression databases

BgeeiQ59FY1.
ExpressionAtlasiQ59FY1. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-6176938.

Structurei

3D structure databases

ProteinModelPortaliQ59FY1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 3 PDZ (DHR) domains.UniRule annotation
Contains SH3 domain.SAAS annotation
Contains SHdomain.SAAS annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000232102.
HOVERGENiHBG107814.
KOiK12075.

Family and domain databases

Gene3Di2.30.42.10. 3 hits.
3.40.50.300. 2 hits.
InterProiIPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR020590. Guanylate_kinase_CS.
IPR019590. MAGUK_PEST_N.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR23119. PTHR23119. 1 hit.
PfamiPF00625. Guanylate_kin. 1 hit.
PF10608. MAGUK_N_PEST. 1 hit.
PF00595. PDZ. 3 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PIRSFiPIRSF001741. MAGUK_DLGH. 1 hit.
SMARTiSM00072. GuKc. 1 hit.
SM00228. PDZ. 3 hits.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF50156. SSF50156. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 3 hits.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59FY1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
APASSLPLGL GPEATTGDTE PPVLEGEPWV RGSVGAEAPG RPPGPRPRSA
60 70 80 90 100
RAPPRVPPPS WSEQCECARE PGGGGGGGGG GGGGVESGVG WGVRAAGGSA
110 120 130 140 150
MHKHQHCCKC PECYEVTRLA ALRRLEPPGY GDWQVPDPYG PGGGNGASAG
160 170 180 190 200
YGGYSSQTLP SQAGATPTPR TKAKLIPTGR DVGPVPPKPV PGKSTPKLNG
210 220 230 240 250
SGPSWWPECT CTNRDWYEQV NGSDGMFKYE EIVLERGNSG LGFSIAGGID
260 270 280 290 300
NPHVPDDPGI FITKIIPGGA AAMDGRLGVN DCVLRVNEVD VSEVVHSRAV
310 320 330 340 350
EALKEAGPVV RLVVRRRQPP PETIMEVNLL KGPKGLGFSI AGGIGNQHIP
360 370 380 390 400
GDNSIYITKI IEGGAAQKDG RLQIGDRLLA VNNTNLQDVR HEEAVASLKN
410 420 430 440 450
TSDMVYLKVA KPGSLHLNDM YAPPDYASTF TALADNHISH NSSLGYLGAV
460 470 480 490 500
ESKVSYPAPP QVPPTRYSPI PRHMLAEEDF TREPRKIILH KGSTGLGFNI
510 520 530 540 550
VGGEDGEGIF VSFILAGGPA DLSGELRRGD RILSVNGVNL RNATHEQAAA
560 570 580 590 600
ALKRAGQSVT IVAQYRPEEY SRFESKIHDL REQMMNSSMS SGSGSLRTSE
610 620 630 640 650
KRSLYVRALF DYDRTRDSCL PSQGLSFSYG DILHVINASD DEWWQARLVT
660 670 680 690 700
PHGESEQIGV IPSKKRVEKK ERARLKTVKF HARTGMIESN RDFPGLSDDY
710 720 730 740 750
YGAKNLKGQE DAILSYEPVT RQEIHYARPV IILGPMKDRV NDDLISEFPH
760 770 780 790 800
KFGSCVPHTT RPRRDNEVDG QDYHFVVSRE QMEKDIQDNK FIEAGQFNDN
810 820 830 840 850
LYGTSIQSVR AVAERGKHCI LDVSGNAIKR LQQAQLYPIA IFIKPKSIEA
860 870 880 890 900
LMEMNRRQTY EQANKIYDKA MKLEQEFGEY FTAIVQGDSL EEIYNKIKQI
910
IEDQSGHYIW VPSPEKL
Length:917
Mass (Da):99,796
Last modified:April 26, 2005 - v1
Checksum:iDFF5EAD57A2C1196
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209328 mRNA. Translation: BAD92565.1.
RefSeqiNP_066943.2. NM_021120.3.
UniGeneiHs.721586.

Genome annotation databases

GeneIDi1741.
KEGGihsa:1741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209328 mRNA. Translation: BAD92565.1 .
RefSeqi NP_066943.2. NM_021120.3.
UniGenei Hs.721586.

3D structure databases

ProteinModelPortali Q59FY1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-6176938.

Proteomic databases

PRIDEi Q59FY1.

Protocols and materials databases

DNASUi 1741.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1741.
KEGGi hsa:1741.

Organism-specific databases

CTDi 1741.
PharmGKBi PA164741439.

Phylogenomic databases

HOGENOMi HOG000232102.
HOVERGENi HBG107814.
KOi K12075.

Miscellaneous databases

GenomeRNAii 1741.
NextBioi 7061.

Gene expression databases

Bgeei Q59FY1.
ExpressionAtlasi Q59FY1. baseline and differential.

Family and domain databases

Gene3Di 2.30.42.10. 3 hits.
3.40.50.300. 2 hits.
InterProi IPR016313. DLG1.
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR020590. Guanylate_kinase_CS.
IPR019590. MAGUK_PEST_N.
IPR027417. P-loop_NTPase.
IPR001478. PDZ.
IPR019583. PDZ_assoc.
IPR001452. SH3_domain.
[Graphical view ]
PANTHERi PTHR23119. PTHR23119. 1 hit.
Pfami PF00625. Guanylate_kin. 1 hit.
PF10608. MAGUK_N_PEST. 1 hit.
PF00595. PDZ. 3 hits.
PF10600. PDZ_assoc. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF001741. MAGUK_DLGH. 1 hit.
SMARTi SM00072. GuKc. 1 hit.
SM00228. PDZ. 3 hits.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 2 hits.
SSF50156. SSF50156. 3 hits.
SSF52540. SSF52540. 1 hit.
PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50106. PDZ. 3 hits.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59FY1_HUMAN
AccessioniPrimary (citable) accession number: Q59FY1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.