Q59FY1 (Q59FY1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Synapse-associated protein 102 variant EMBL BAD92565.1
Organism	Homo sapiens (Human) EMBL BAD92565.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	917 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338 SAAS SAAS008145 Contains 3 PDZ (DHR) domains. RuleBase RU003354

Ontologies

Keywords
Domain	SH3 domain SAAS SAAS008145 RuleBase RU003338
Gene Ontology (GO)
Biological_process	establishment of planar polarity Inferred from electronic annotation. Source: Compara establishment or maintenance of epithelial cell apical/basal polarity Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from electronic annotation. Source: Compara dendritic shaft Inferred from electronic annotation. Source: Compara growth cone Inferred from electronic annotation. Source: Compara neuronal cell body Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara synapse Inferred from electronic annotation. Source: Compara tight junction Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92565.1

Sequences

	Sequence		Length	Mass (Da)
	Q59FY1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: DFF5EAD57A2C1196	FASTA	917	99,796
	10 20 30 40 50 60 APASSLPLGL GPEATTGDTE PPVLEGEPWV RGSVGAEAPG RPPGPRPRSA RAPPRVPPPS 70 80 90 100 110 120 WSEQCECARE PGGGGGGGGG GGGGVESGVG WGVRAAGGSA MHKHQHCCKC PECYEVTRLA 130 140 150 160 170 180 ALRRLEPPGY GDWQVPDPYG PGGGNGASAG YGGYSSQTLP SQAGATPTPR TKAKLIPTGR 190 200 210 220 230 240 DVGPVPPKPV PGKSTPKLNG SGPSWWPECT CTNRDWYEQV NGSDGMFKYE EIVLERGNSG 250 260 270 280 290 300 LGFSIAGGID NPHVPDDPGI FITKIIPGGA AAMDGRLGVN DCVLRVNEVD VSEVVHSRAV 310 320 330 340 350 360 EALKEAGPVV RLVVRRRQPP PETIMEVNLL KGPKGLGFSI AGGIGNQHIP GDNSIYITKI 370 380 390 400 410 420 IEGGAAQKDG RLQIGDRLLA VNNTNLQDVR HEEAVASLKN TSDMVYLKVA KPGSLHLNDM 430 440 450 460 470 480 YAPPDYASTF TALADNHISH NSSLGYLGAV ESKVSYPAPP QVPPTRYSPI PRHMLAEEDF 490 500 510 520 530 540 TREPRKIILH KGSTGLGFNI VGGEDGEGIF VSFILAGGPA DLSGELRRGD RILSVNGVNL 550 560 570 580 590 600 RNATHEQAAA ALKRAGQSVT IVAQYRPEEY SRFESKIHDL REQMMNSSMS SGSGSLRTSE 610 620 630 640 650 660 KRSLYVRALF DYDRTRDSCL PSQGLSFSYG DILHVINASD DEWWQARLVT PHGESEQIGV 670 680 690 700 710 720 IPSKKRVEKK ERARLKTVKF HARTGMIESN RDFPGLSDDY YGAKNLKGQE DAILSYEPVT 730 740 750 760 770 780 RQEIHYARPV IILGPMKDRV NDDLISEFPH KFGSCVPHTT RPRRDNEVDG QDYHFVVSRE 790 800 810 820 830 840 QMEKDIQDNK FIEAGQFNDN LYGTSIQSVR AVAERGKHCI LDVSGNAIKR LQQAQLYPIA 850 860 870 880 890 900 IFIKPKSIEA LMEMNRRQTY EQANKIYDKA MKLEQEFGEY FTAIVQGDSL EEIYNKIKQI 910 IEDQSGHYIW VPSPEKL

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92565.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209328 mRNA. Translation: BAD92565.1.
IPI	IPI00023343.
RefSeq	NP_066943.2. NM_021120.3.
UniGene	Hs.721586.
3D structure databases
ProteinModelPortal	Q59FY1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59FY1.
Proteomic databases
PRIDE	Q59FY1.
Protocols and materials databases
DNASU	1741.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1741.
KEGG	hsa:1741.
Organism-specific databases
CTD	1741.
PharmGKB	PA164741439.
Phylogenomic databases
HOGENOM	HOG000232102.
HOVERGEN	HBG107814.
KO	K12075.
Gene expression databases
ArrayExpress	Q59FY1.
Bgee	Q59FY1.
Family and domain databases
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR016313. M-assoc_guanylate_kinase. IPR019590. MAGUK_PEST_N. IPR001478. PDZ. IPR019583. PDZ_assoc. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00625. Guanylate_kin. 1 hit. PF10608. MAGUK_N_PEST. 1 hit. PF00595. PDZ. 3 hits. PF10600. PDZ_assoc. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PIRSF	PIRSF001741. MAGUK_DLGH. 1 hit.
SMART	SM00072. GuKc. 1 hit. SM00228. PDZ. 3 hits. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50156. PDZ. 3 hits. SSF50044. SH3. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. PS50106. PDZ. 3 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	1741.
NextBio	7061.

Entry information

Entry name

Q59FY1_HUMAN

Accession

Primary (citable) accession number: Q59FY1

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.