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Protein
Submitted name:

Elongation factor, RNA polymerase II, 2 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Elongation factorImported

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Elongation factor, RNA polymerase II, 2 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134935340.

PTM / Processingi

Proteomic databases

PaxDbiQ59FW6.
PeptideAtlasiQ59FW6.
PRIDEiQ59FW6.

Expressioni

Gene expression databases

BgeeiENSG00000118985.
GenevisibleiQ59FW6. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000237853.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 170ELLInterPro annotationAdd BLAST170
Domaini411 – 512Occludin_ELLInterPro annotationAdd BLAST102

Phylogenomic databases

eggNOGiKOG4796. Eukaryota.
ENOG410ZNGU. LUCA.
HOVERGENiHBG005578.
KOiK15183.

Family and domain databases

InterProiIPR031176. ELL/occludin.
IPR031179. ELL2.
IPR019464. ELL_N.
IPR010844. Occludin_ELL.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR23288. PTHR23288. 1 hit.
PTHR23288:SF8. PTHR23288:SF8. 1 hit.
PfamiPF10390. ELL. 1 hit.
PF07303. Occludin_ELL. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q59FW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ITVCATNDSY QMTRERMTQA EEESRNRSTK VIKPGGPYVG KRVQIRKAPQ
60 70 80 90 100
AVSDTVPERK RSTPMNPANT IRKTHSSSTI SQRPYRDRVI HLLALKAYKK
110 120 130 140 150
PELLARLQKD GVNQKDKNSL GAILQQVANL NSKDLSYTLK DYVFKELQRD
160 170 180 190 200
WPGYSEIDRR SLESVLSRKL NPSQNAAGTS RSESPVCSSR DAVSSPQKRL
210 220 230 240 250
LDSEFIDPLM NKKARISHLT NRVPPTLNGH LNPTSEKSAA GLPLPPAAAA
260 270 280 290 300
IPTPPPLPST YLPISHPPQI VNSNSNSPST PEGRGTQDLP VDSFSQNDSI
310 320 330 340 350
YEDQQDKYTS RTSLETLPPG SVLLKCPKPM EENHSMSHKK SKKKSKKHKE
360 370 380 390 400
KDQIKKHDIE TIEEKEEDLK REEEIAKLNN SSPNSSGGVK EDCTASMEPS
410 420 430 440 450
AIELPDYLIK YIAIVSYEQR QNYKDDFNAE YDEYRALHAR METVARRFIK
460 470 480 490 500
LDAQRKRLSP GSKEYQNVHE EVLQEYQKIK QSSPNYHEEK YRCEYLHNKL
510
AHIKRLIGEF DQQQAESWS
Length:519
Mass (Da):59,004
Last modified:April 26, 2005 - v1
Checksum:i6CCD0AFF04194A6F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209343 mRNA. Translation: BAD92580.1.
RefSeqiNP_036213.2. NM_012081.5.
UniGeneiHs.192221.
Hs.708710.

Genome annotation databases

GeneIDi22936.
KEGGihsa:22936.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209343 mRNA. Translation: BAD92580.1.
RefSeqiNP_036213.2. NM_012081.5.
UniGeneiHs.192221.
Hs.708710.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000237853.

Proteomic databases

PaxDbiQ59FW6.
PeptideAtlasiQ59FW6.
PRIDEiQ59FW6.

Protocols and materials databases

DNASUi22936.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22936.
KEGGihsa:22936.

Organism-specific databases

CTDi22936.
PharmGKBiPA134935340.

Phylogenomic databases

eggNOGiKOG4796. Eukaryota.
ENOG410ZNGU. LUCA.
HOVERGENiHBG005578.
KOiK15183.

Miscellaneous databases

GenomeRNAii22936.

Gene expression databases

BgeeiENSG00000118985.
GenevisibleiQ59FW6. HS.

Family and domain databases

InterProiIPR031176. ELL/occludin.
IPR031179. ELL2.
IPR019464. ELL_N.
IPR010844. Occludin_ELL.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR23288. PTHR23288. 1 hit.
PTHR23288:SF8. PTHR23288:SF8. 1 hit.
PfamiPF10390. ELL. 1 hit.
PF07303. Occludin_ELL. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ59FW6_HUMAN
AccessioniPrimary (citable) accession number: Q59FW6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: September 7, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.