Q59FS7 (Q59FS7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 variant EMBL BAD92619.1
Organism	Homo sapiens (Human) EMBL BAD92619.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	676 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the DEAD box helicase family. RuleBase RU000492

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000492 Hydrolase
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD92619.1

Sequences

	Sequence		Length	Mass (Da)
	Q59FS7 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 413F73294C69FED1	FASTA	676	75,048
	10 20 30 40 50 60 ASPHATMKLK DTKSRPKQSS CGKFQTKGIK VVGKWKEVKI DPNMFADGQM DDLVCFEELT 70 80 90 100 110 120 DYQLVSPAKN PSSLFSKEAP KRKAQAVSEE EEEEEGKSSS PKKKIKLKKS KNVATEGTST 130 140 150 160 170 180 QKEFEVKDPE LEVQGDDMVC DDPEAGEMTS ENLVQTAPKK KKNKGKKGLE PSQSTAAKVP 190 200 210 220 230 240 KKAKTWIPEV HDQKADVSAW KDLFVPRPVL RALSFLGFSA PTPIQALTLA PAIRDKLDIL 250 260 270 280 290 300 GAAETGSGKT LAFAIPMIHA VLQWQKRNAA PPPSNTEAPP GETRTEAGAE TRSPGKAEAE 310 320 330 340 350 360 SDALPDDTVI ESEALPSDIA AEARAKTGGT VSDQALLFGD DDAGEGPSSL IREKPVPKQN 370 380 390 400 410 420 ENEEENLDKE QTGNLKQELD DKSATCKAYP KRPLLGLVLT PTRELAVQVK QHIDAVARFT 430 440 450 460 470 480 GIKTAILVGG MSTQKQQRML NRRPEIVVAT PGRLWELIKE KHYHLRNLRQ LRCLVVDEAD 490 500 510 520 530 540 RMVEKGHFAE LSQLLEMLND SQYNPKRQTL VFSATLTLVH QAPARILHKK HTKKMDKTAK 550 560 570 580 590 600 LDLLMQKIGM RGKPKVIDLT RNEATVETLT ETKIHCETDE KDFYLYYFLM QYPGRSLVFA 610 620 630 640 650 660 NSISCIKRLS GLLKVLDIMP LTLHACMHQK QRLRNLEQFA RLEDCVLLAT DVAARGLDIP 670 KVQHVIHYQV GASENL

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD92619.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209382 mRNA. Translation: BAD92619.1.
IPI	IPI00006987.
UniGene	Hs.510328.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q59FS7.
Proteomic databases
PRIDE	Q59FS7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG104200.
Gene expression databases
ArrayExpress	Q59FS7.
Family and domain databases
InterPro	IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR014001. Helicase_ATP-bd. IPR001650. Helicase_C. IPR000629. RNA-helicase_DEAD-box_CS. IPR014014. RNA_helicase_DEAD_Q_motif. [Graphical view]
Pfam	PF00270. DEAD. 1 hit. PF00271. Helicase_C. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS00039. DEAD_ATP_HELICASE. 1 hit. PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS51195. Q_MOTIF. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q59FS7_HUMAN

Accession

Primary (citable) accession number: Q59FS7

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	March 21, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.