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Protein
Submitted name:

Guanine nucleotide-binding protein G, alpha subunit variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G, alpha subunit variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  • lysosomal membrane Source: UniProtKB
  • photoreceptor outer segment Source: AgBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ59FM5.
PeptideAtlasiQ59FM5.
PRIDEiQ59FM5.

Expressioni

Gene expression databases

BgeeiENSG00000088256.

Interactioni

Protein-protein interaction databases

IntActiQ59FM5. 3 interactors.
STRINGi9606.ENSP00000078429.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0085. Eukaryota.
ENOG410XNVQ. LUCA.
HOVERGENiHBG063184.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR000654. Gprotein_alpha_Q.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
PR00442. GPROTEINAQ.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q59FM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LESMMACCLS DEVKESKRIN AEIEKQLRRD KRDARRELKL LLLGTGESGK
60 70 80 90 100
STFIKQMRII HGAGYSEEDK RGFTKLVYQN IFTAMQAMIR AMETLKILYK
110 120 130 140 150
YEQNKANALL IREVDVEKVT TFEHQYVSAI KTLWEDPGIQ ECYDRRREYQ
160 170 180 190 200
LSDSAKYYLT DVDRIATLGY LPTQQDVLRV RVPTTGIIEY PFDLENIIFR
210 220 230 240 250
MVDVGGQRSE RRKWIHCFEN VTSIMFLVAL SEYDQVLVES DNENRMEESK
260 270 280 290 300
ALFRTIITYP WFQNSSVILF LNKKDLLEDK ILYSHLVDYF PEFDGPQRDA
310 320 330 340 350
QAAREFILKM FVDLNPDSDK IIYSHFTCAT DTENIRFVFA AVKDTILQLN

LKEYNLV
Length:357
Mass (Da):41,891
Last modified:April 26, 2005 - v1
Checksum:i60D09BF70DA5B9EB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209435 mRNA. Translation: BAD92672.1.
UniGeneiHs.650575.
Hs.654784.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209435 mRNA. Translation: BAD92672.1.
UniGeneiHs.650575.
Hs.654784.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ59FM5. 3 interactors.
STRINGi9606.ENSP00000078429.

Proteomic databases

PaxDbiQ59FM5.
PeptideAtlasiQ59FM5.
PRIDEiQ59FM5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0085. Eukaryota.
ENOG410XNVQ. LUCA.
HOVERGENiHBG063184.

Gene expression databases

BgeeiENSG00000088256.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR000654. Gprotein_alpha_Q.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
PR00442. GPROTEINAQ.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ59FM5_HUMAN
AccessioniPrimary (citable) accession number: Q59FM5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 30, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.