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Protein
Submitted name:

DEAD box polypeptide 17 isoform p82 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HelicaseUniRule annotation, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD box polypeptide 17 isoform p82 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27206.

PTM / Processingi

Proteomic databases

EPDiQ59F66.
PaxDbiQ59F66.
PeptideAtlasiQ59F66.
PRIDEiQ59F66.

PTM databases

iPTMnetiQ59F66.

Expressioni

Gene expression databases

GenevisibleiQ59F66. HS.

Interactioni

Protein-protein interaction databases

IntActiQ59F66. 3 interactions.
STRINGi9606.ENSP00000380033.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini173 – 20129Q_MOTIFInterPro annotationAdd
BLAST
Domaini204 – 379176Helicase ATP-bindingInterPro annotationAdd
BLAST
Domaini407 – 554148Helicase C-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0331. Eukaryota.
COG0513. LUCA.
HOGENOMiHOG000268804.
HOVERGENiHBG015893.
PhylomeDBiQ59F66.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59F66-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PNLPTGFVAP ILCVLLPSPT REAATVASAT GDSASERESA APAAAPTAEA
60 70 80 90 100
PPPSVVTRPE PQALPSPAIR APLPDLYPFG TMRGGGFGDR DRDRDRGGFG
110 120 130 140 150
ARGGGGLPPK KFGNPGERLR KKKWDLSELP KFEKNFYVEH PEVARLTPYE
160 170 180 190 200
VDELRRKKEI TVRGGDVCPK PVFAFHHANF PQYVMDVLMD QHFTEPTPIQ
210 220 230 240 250
CQGFPLALSG RDMVGIAQTG SGKTLAYLLP AIVHINHQPY LERGDGPICL
260 270 280 290 300
VLAPTRELAQ QVQQVADDYG KCSRLKSTCI YGGAPKGPQI RDLERGVEIC
310 320 330 340 350
IATPGRLIDF LESGKTNLRR CTYLVLDEAD RMLDMGFEPQ IRKIVDQIRP
360 370 380 390 400
DRQTLMWSAT WPKEVRQLAE DFLRDYTQIN VGNLELSANH NILQIVDVCM
410 420 430 440 450
ESEKDHKLIQ LMEEIMAEKE NKTIIFVETK RRCDDLTRRM RRDGWPAMCI
460 470 480 490 500
HGDKSQPERD WVLNEFRSGK APILIATDVA SRGLDVEDVK FVINYDYPNS
510 520 530 540 550
SEDYVHRIGR TARSTNKGTA YTFFTPGNLK QARELIKVLE EANQAINPKL
560 570 580 590 600
MQLVDHRGGG GGGGKGGRSR YRTTSSANNP NLMYQDECDR RLRGVKDGGR
610 620 630 640 650
RDSASYRDRS ETDRAGYANG SGYGSPNSAF GAQAGQYTYG QGTYGAAAYG
660 670 680 690 700
TSSYTAQEYG AGTYGASSTT STGRSSQSSS QQFSGIGRSG QQPQPLMSQQ
710 720 730
FAQPPGATNT LLLLPLLLLH VNETTQVVVT PADLITF
Length:737
Mass (Da):81,067
Last modified:April 26, 2005 - v1
Checksum:iFA5E2A47B8844D1C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209595 mRNA. Translation: BAD92832.1.
RefSeqiNP_001091974.1. NM_001098504.1.
UniGeneiHs.528305.
Hs.706116.

Genome annotation databases

GeneIDi10521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209595 mRNA. Translation: BAD92832.1.
RefSeqiNP_001091974.1. NM_001098504.1.
UniGeneiHs.528305.
Hs.706116.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ59F66. 3 interactions.
STRINGi9606.ENSP00000380033.

PTM databases

iPTMnetiQ59F66.

Proteomic databases

EPDiQ59F66.
PaxDbiQ59F66.
PeptideAtlasiQ59F66.
PRIDEiQ59F66.

Protocols and materials databases

DNASUi10521.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10521.

Organism-specific databases

CTDi10521.
PharmGKBiPA27206.

Phylogenomic databases

eggNOGiKOG0331. Eukaryota.
COG0513. LUCA.
HOGENOMiHOG000268804.
HOVERGENiHBG015893.
PhylomeDBiQ59F66.

Miscellaneous databases

GenomeRNAii10521.

Gene expression databases

GenevisibleiQ59F66. HS.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ59F66_HUMAN
AccessioniPrimary (citable) accession number: Q59F66
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 6, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.