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Unreviewed, UniProtKB/TrEMBL Q59F39 (Q59F39_HUMAN)

Last modified January 19, 2010. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    IL2-inducible T-cell kinase variant EMBL BAD92859.1
OrganismHomo sapiens (Human) EMBL BAD92859.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length376 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Contains 1 PH domain.

Contains 1 SH3 domain.

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Ontologies

Keywords
   DomainSH3 domain RuleBase RU003338V3
   Molecular functionKinase EMBL BAD92859.1
Transferase
Gene Ontology (GO)
   Biological processintracellular signaling cascade

Inferred from electronic annotation. Source: InterPro

   Molecular functionkinase activity

Inferred from electronic annotation. Source: UniProtKB-KW

protein binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAD92859.1

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Sequences

Sequence LengthMass (Da)Tools
Q59F39-1 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 0D9F9C6D6C256E16

FASTA37643,815
        10         20         30         40         50         60 
VEGKLPLSSS LKINCLHIAF FAPKLFPLVV LRGDAQGAPP FKNWIMNNFI LLEEQLIKKS 

        70         80         90        100        110        120 
QQKRRTSPSN FKVRFFVLTK ASLAYFEDRH GKKRTLKGSI ELSRIKCVEI VKSDISIPCH 

       130        140        150        160        170        180 
YKYPFQVVHD NYLLYVFAPD RESRQRWVLA LKEETRNNNS LVPKYHPNFW MDGKWRCCSQ 

       190        200        210        220        230        240 
LEKLATGCAQ YDPTKNASKK PLPPTPEDNR RPLWEPEETV VIALYDYQTN DPQELALRRN 

       250        260        270        280        290        300 
EEYCLLDSSE IHWWRVQDRN GHEGYVPSSY LVEKSPNNLE TYEWYNKSIS RDKAEKLLLD 

       310        320        330        340        350        360 
TGKEGAFMVR DSRTAGTYTV SVFTKAVVSE NNPCIKHYHI KETNDNPKRY YVAEKYVFDS 

       370 
IPLLINYHQH NGGGKL

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References

[1]"Homo sapiens protein coding cDNA."
Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Spleen EMBL BAD92859.1.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB209622 mRNA. Translation: BAD92859.1.
IPIIPI00555925.
UniGeneHs.558348

3D structure databases

SMRQ59F39. Positions 18-44, 50-191, 161-214, 207-284, 217-374.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ59F39.

Genome annotation databases

EnsemblENST00000231189; ENSP00000231189; ENSG00000113263; Homo sapiens. [Genome view]

Phylogenomic databases

HOVERGENQ59F39.

Gene expression databases

ArrayExpressQ59F39.
BgeeQ59F39.

Family and domain databases

InterProIPR011993. PH_type.
IPR001849. Pleckstrin_homology.
IPR000980. SH2.
IPR001452. SH3_domain.
IPR020685. Tyr_prot_kinase.
IPR001562. Znf_Btk_motif.
[Graphical view]
Gene3DG3DSA:2.30.29.30. PH_type. 1 hit.
G3DSA:3.30.505.10. SH2. 1 hit.
PANTHERPTHR23256. Tyr_prot_kinase. 1 hit.
PfamPF00779. BTK. 1 hit.
PF00169. PH. 1 hit.
PF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00401. SH2DOMAIN.
PR00402. TECBTKDOMAIN.
SMARTSM00107. BTK. 1 hit.
SM00233. PH. 1 hit.
SM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
PROSITEPS50003. PH_DOMAIN. 1 hit.
PS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
PS51113. ZF_BTK. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ59F39_HUMAN
AccessionPrimary (citable) accession number: Q59F39
Entry history
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: January 19, 2010
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information