Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interleukin 10 receptor, alpha variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 10 receptor, alpha variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei234 – 258HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ59F35.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000227752.

Structurei

3D structure databases

ProteinModelPortaliQ59F35.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 109Fibronectin type-IIIInterPro annotationAdd BLAST94

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGAG. Eukaryota.
ENOG410YMSK. LUCA.
HOVERGENiHBG052056.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF01108. Tissue_fac. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q59F35-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NWGHQCLPPL PAVVLTLFSP GTELPSPPSV WFEAEFFHHI LHWTPIPNQS
60 70 80 90 100
ESTCYEVALL RYGIESWNSI SNCSQTLSYD LTAVTLDLYH SNGYRARVRA
110 120 130 140 150
VDGSRHSNWT VTNTRFSVDE VTLTVGSVNL EIHNGFILGK IQLPRPKMAP
160 170 180 190 200
ANDTYESIFS HFREYEIAIR KVPGNFTFTH KKVKHENFSL LTSGEVGEFC
210 220 230 240 250
VQVKPSVASR SNKGMWSKEE CISLTRQYFT VTNVIIFFAF VLLLSGALAY
260 270 280 290 300
CLALQLYVRR RKKLPSVLLF KKPSPFIFIS QRPSPETQDT IHPLDEEAFL
310 320 330 340 350
KVSPELKNLD LHGSTDSGFG STKPSLQTEE PQFLLPDPHP QADRTLGNRE
360 370 380 390 400
PPVLGDSCSS GSSNSTDSGI CLQEPSLSPS TGPTWEQQVG SNSRGQDDSG
410 420 430 440 450
IDLVQNSEGR AGDTQGGSAL GHHSPPEPEV PGEEDPAAVA FQGYLRQTRC
460 470 480 490 500
AEEKATKTGC LEEESPLTDG LGPKFGRCLV DEAGLHPPAL AKGYLKQDPL
510 520 530 540 550
EMTLASSGAP TGQWNQPTEE WSLLALSSCS DLGISDWSFA HDLAPLGCVA
560 570
APGGLLGSFN SDLVTLPLIS SLQSSE
Length:576
Mass (Da):62,887
Last modified:April 26, 2005 - v1
Checksum:i4C56A62A63645C2B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209626 mRNA. Translation: BAD92863.1.
UniGeneiHs.504035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209626 mRNA. Translation: BAD92863.1.
UniGeneiHs.504035.

3D structure databases

ProteinModelPortaliQ59F35.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000227752.

Proteomic databases

PaxDbiQ59F35.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IGAG. Eukaryota.
ENOG410YMSK. LUCA.
HOVERGENiHBG052056.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF01108. Tissue_fac. 1 hit.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ59F35_HUMAN
AccessioniPrimary (citable) accession number: Q59F35
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: April 13, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.