Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Major histocompatibility complex, class II, DQ alpha 1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Biological processImmunity

Names & Taxonomyi

Protein namesi
Submitted name:
Major histocompatibility complex, class II, DQ alpha 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, MHC IISAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_500425259930 – 254Sequence analysisAdd BLAST225

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ59F33.
PRIDEiQ59F33.

Structurei

3D structure databases

ProteinModelPortaliQ59F33.
SMRiQ59F33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 199Ig-likeInterPro annotationAdd BLAST81

Sequence similaritiesi

Belongs to the MHC class II family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiENOG410IZMF. Eukaryota.
ENOG410YHX9. LUCA.
HOVERGENiHBG006862.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiView protein in InterPro
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR001003. MHC_II_a_N.
PfamiView protein in Pfam
PF07654. C1-set. 1 hit.
PF00993. MHC_II_alpha. 1 hit.
SMARTiView protein in SMART
SM00407. IGc1. 1 hit.
SM00920. MHC_II_alpha. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q59F33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GCLGKRMILN KALLLGALAL TTVMSPCGGE DIVADHVASC GVNLYQFYGP
60 70 80 90 100
SGQYTHEFDG DEQFYVDLER KETAWRWPEF SKFGGFDPQG ALRNMAVAKH
110 120 130 140 150
NLNIMIKRYN STAATNEVPE VTVFSKSPVT LGQPNTLICL VDNIFPPVVN
160 170 180 190 200
ITWLSNGQSV TEGVSETSFL SKSDHSFFKI SYLTFLPSAD EIYDCKVEHW
210 220 230 240 250
GLDQPLLKHW GKDEFHHFLI LSCLSSSELP AFYSYIQKLV FHTSWVSFLS

LFFF
Length:254
Mass (Da):28,604
Last modified:April 26, 2005 - v1
Checksum:i2392D7B27D3C3327
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209628 mRNA. Translation: BAD92865.1.
UniGeneiHs.387679.
Hs.591798.
Hs.706240.

Similar proteinsi

Entry informationi

Entry nameiQ59F33_HUMAN
AccessioniPrimary (citable) accession number: Q59F33
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: September 27, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.