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Q59F33

- Q59F33_HUMAN

UniProt

Q59F33 - Q59F33_HUMAN

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Protein
Submitted name: Major histocompatibility complex, class II, DQ alpha 1 variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
Major histocompatibility complex, class II, DQ alpha 1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class II protein complex Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IISAAS annotations

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Proteomic databases

PRIDEiQ59F33.

Structurei

3D structure databases

ProteinModelPortaliQ59F33.

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class II family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG006862.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR001003. MHC_II_a_N.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00993. MHC_II_alpha. 1 hit.
[Graphical view]
SMARTiSM00407. IGc1. 1 hit.
SM00920. MHC_II_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59F33-1 [UniParc]FASTAAdd to Basket

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GCLGKRMILN KALLLGALAL TTVMSPCGGE DIVADHVASC GVNLYQFYGP    50
SGQYTHEFDG DEQFYVDLER KETAWRWPEF SKFGGFDPQG ALRNMAVAKH 100
NLNIMIKRYN STAATNEVPE VTVFSKSPVT LGQPNTLICL VDNIFPPVVN 150
ITWLSNGQSV TEGVSETSFL SKSDHSFFKI SYLTFLPSAD EIYDCKVEHW 200
GLDQPLLKHW GKDEFHHFLI LSCLSSSELP AFYSYIQKLV FHTSWVSFLS 250
LFFF 254
Length:254
Mass (Da):28,604
Last modified:April 26, 2005 - v1
Checksum:i2392D7B27D3C3327
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209628 mRNA. Translation: BAD92865.1.
UniGeneiHs.387679.
Hs.591798.
Hs.706240.

Genome annotation databases

UCSCiuc003obt.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209628 mRNA. Translation: BAD92865.1 .
UniGenei Hs.387679.
Hs.591798.
Hs.706240.

3D structure databases

ProteinModelPortali Q59F33.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q59F33.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc003obt.1. human.

Phylogenomic databases

HOVERGENi HBG006862.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR001003. MHC_II_a_N.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00993. MHC_II_alpha. 1 hit.
[Graphical view ]
SMARTi SM00407. IGc1. 1 hit.
SM00920. MHC_II_alpha. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SpleenImported.

Entry informationi

Entry nameiQ59F33_HUMAN
AccessioniPrimary (citable) accession number: Q59F33
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 9, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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