ID   Q59F22_HUMAN            Unreviewed;       189 AA.
AC   Q59F22;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Interferon stimulated gene 20kDa variant {ECO:0000313|EMBL:BAD92876.1};
DE   Flags: Fragment;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAD92876.1};
RN   [1] {ECO:0000313|EMBL:BAD92876.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Spleen {ECO:0000313|EMBL:BAD92876.1};
RA   Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.,
RA   Ohara O., Nagase T., Kikuno R.F.;
RT   "Homo sapiens protein coding cDNA.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AB209639; BAD92876.1; -; mRNA.
DR   AlphaFoldDB; Q59F22; -.
DR   SMR; Q59F22; -.
DR   MaxQB; Q59F22; -.
DR   PeptideAtlas; Q59F22; -.
DR   PhylomeDB; Q59F22; -.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR   InterPro; IPR047021; REXO1/3/4-like.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR12801:SF59; INTERFERON-STIMULATED GENE 20 KDA PROTEIN; 1.
DR   PANTHER; PTHR12801; RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED; 1.
DR   SMART; SM00479; EXOIII; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   2: Evidence at transcript level;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022839}.
FT   DOMAIN          32..179
FT                   /note="Exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00479"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAD92876.1"
SQ   SEQUENCE   189 AA;  21229 MW;  1056417DE0C03F0D CRC64;
     PLLLHSSAPE GVQVGFWHRM KLSGVRRVLV QSLLFKDDTF EAQGGLIICP RSHSQSRRDC
     SLASPSPTQK MLGHVGVGTC LPGQILQLLK GKLVVGHDLK HDFQALKEDM SGYTIYDTST
     DRLLWREAKL DHCRRVSLRV LSERLLHKSI QNSLLGHSSV EDARATMELY QISQRIRARR
     GLPRLAVSD
//