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Q59F19

- Q59F19_HUMAN

UniProt

Q59F19 - Q59F19_HUMAN

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Protein
Submitted name: Proto-oncogene tyrosine-protein kinase ABL1 variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. non-membrane spanning protein tyrosine kinase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Proto-oncogene tyrosine-protein kinase ABL1 variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiQ59F19.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59F19.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG102468.

    Family and domain databases

    InterProiIPR015015. F-actin_binding.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    IPR008266. Tyr_kinase_AS.
    IPR020635. Tyr_kinase_cat_dom.
    [Graphical view]
    PfamiPF08919. F_actin_bind. 1 hit.
    PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view]
    PRINTSiPR00109. TYRKINASE.
    SMARTiSM00808. FABD. 1 hit.
    SM00219. TyrKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59F19-1 [UniParc]FASTAAdd to Basket

    « Hide

    WQALRLLREP LQHPGRVGSS SFNGGRRAHH HAPLSSPKAQ QAHCLWCVPQ    50
    LRQVGDGTHG HHHEAQAGGG QYGEVYEGVW KKYSLTVAVK TLKEDTMEVE 100
    EFLKEAAVMK EIKHPNLVQL LGVCTREPPF YIITEFMTYG NLLDYLRECN 150
    RQEVNAVVLL YMATQISSAM EYLEKKNFIH RDLAARNCLV GENHLVKVAD 200
    FGLSRLMTGD TYTAHAGAKF PIKWTAPESL AYNKFSIKSD VWAFGVLLWE 250
    IATYGMSPYP GIDLSQVYEL LEKDYRMERP EGCPEKVYEL MRACWQWNPS 300
    DRPSFAEIHQ AFETMFQESS ISDEVEKELG KQGVRGAVST LLQAPELPTK 350
    TRTSRRAAEH RDTTDVPEMP HSKGQGESDP LDHEPAVSPL LPRKERGPPE 400
    GGLNEDERLL PKDKKTNLFS ALIKKKKKTA PTPPKRSSSF REMDGQPERR 450
    GAGEEEGRDI SNGALAFTPL DTADPAKSPK PSNGAGVPNG ALRESGGSGF 500
    RSPHLWKKSS TLTSSRLATG EEEGGGSSSK RFLRSCSASC VPHGAKDTEW 550
    RSVTLPRDLQ STGRQFDSST FGGHKSEKPA LPRKRAGENR SDQVTRGTVT 600
    PPPRLVKKNE EAADEVFKDI MESSPGSSPP NLTPKPLRRQ VTVAPASGLP 650
    HKEEAGKGSA LGTPAAAEPV TPTSKAGSGA PGGTSKGPAE ESRVRRHKHS 700
    SESPGRDKGK LSRLKPAPPP PPAASAGKAG GKPSQSPSQE AAGEAVLGAK 750
    TKATSLVDAV NSDAAKPSQP GEGLKKPVLP ATPKPQSAKP SGTPISPAPV 800
    PSTLPSASSA LAGDQPSSTA FIPLISTRVS LRKTRQPPER IASGAITKGV 850
    VLDSTEALCL AISRNSEQMA SHSAVLEAGK NLYTFCVSYV DSIQQMRNKF 900
    AFREAINKLE NNLRELQICP ATAGSGPAAT QDFSKLLSSV KEISDIVQR 949
    Length:949
    Mass (Da):102,591
    Last modified:April 26, 2005 - v1
    Checksum:i219200BE06EBCEEA
    GO

    Non-terminal residue

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209642 mRNA. Translation: BAD92879.1.
    UniGeneiHs.431048.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209642 mRNA. Translation: BAD92879.1 .
    UniGenei Hs.431048.

    3D structure databases

    ProteinModelPortali Q59F19.
    ModBasei Search...

    Proteomic databases

    PRIDEi Q59F19.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG102468.

    Family and domain databases

    InterProi IPR015015. F-actin_binding.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
    IPR008266. Tyr_kinase_AS.
    IPR020635. Tyr_kinase_cat_dom.
    [Graphical view ]
    Pfami PF08919. F_actin_bind. 1 hit.
    PF07714. Pkinase_Tyr. 1 hit.
    [Graphical view ]
    PRINTSi PR00109. TYRKINASE.
    SMARTi SM00808. FABD. 1 hit.
    SM00219. TyrKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00109. PROTEIN_KINASE_TYR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: SpleenImported.

    Entry informationi

    Entry nameiQ59F19_HUMAN
    AccessioniPrimary (citable) accession number: Q59F19
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: July 9, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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