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Q59F19 (Q59F19_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL BAD92879.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length949 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains protein kinase domain. SAAS SAAS008266

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAD92879.1

Sequences

Sequence LengthMass (Da)Tools
Q59F19 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 219200BE06EBCEEA

FASTA949102,591
        10         20         30         40         50         60 
WQALRLLREP LQHPGRVGSS SFNGGRRAHH HAPLSSPKAQ QAHCLWCVPQ LRQVGDGTHG 

        70         80         90        100        110        120 
HHHEAQAGGG QYGEVYEGVW KKYSLTVAVK TLKEDTMEVE EFLKEAAVMK EIKHPNLVQL 

       130        140        150        160        170        180 
LGVCTREPPF YIITEFMTYG NLLDYLRECN RQEVNAVVLL YMATQISSAM EYLEKKNFIH 

       190        200        210        220        230        240 
RDLAARNCLV GENHLVKVAD FGLSRLMTGD TYTAHAGAKF PIKWTAPESL AYNKFSIKSD 

       250        260        270        280        290        300 
VWAFGVLLWE IATYGMSPYP GIDLSQVYEL LEKDYRMERP EGCPEKVYEL MRACWQWNPS 

       310        320        330        340        350        360 
DRPSFAEIHQ AFETMFQESS ISDEVEKELG KQGVRGAVST LLQAPELPTK TRTSRRAAEH 

       370        380        390        400        410        420 
RDTTDVPEMP HSKGQGESDP LDHEPAVSPL LPRKERGPPE GGLNEDERLL PKDKKTNLFS 

       430        440        450        460        470        480 
ALIKKKKKTA PTPPKRSSSF REMDGQPERR GAGEEEGRDI SNGALAFTPL DTADPAKSPK 

       490        500        510        520        530        540 
PSNGAGVPNG ALRESGGSGF RSPHLWKKSS TLTSSRLATG EEEGGGSSSK RFLRSCSASC 

       550        560        570        580        590        600 
VPHGAKDTEW RSVTLPRDLQ STGRQFDSST FGGHKSEKPA LPRKRAGENR SDQVTRGTVT 

       610        620        630        640        650        660 
PPPRLVKKNE EAADEVFKDI MESSPGSSPP NLTPKPLRRQ VTVAPASGLP HKEEAGKGSA 

       670        680        690        700        710        720 
LGTPAAAEPV TPTSKAGSGA PGGTSKGPAE ESRVRRHKHS SESPGRDKGK LSRLKPAPPP 

       730        740        750        760        770        780 
PPAASAGKAG GKPSQSPSQE AAGEAVLGAK TKATSLVDAV NSDAAKPSQP GEGLKKPVLP 

       790        800        810        820        830        840 
ATPKPQSAKP SGTPISPAPV PSTLPSASSA LAGDQPSSTA FIPLISTRVS LRKTRQPPER 

       850        860        870        880        890        900 
IASGAITKGV VLDSTEALCL AISRNSEQMA SHSAVLEAGK NLYTFCVSYV DSIQQMRNKF 

       910        920        930        940 
AFREAINKLE NNLRELQICP ATAGSGPAAT QDFSKLLSSV KEISDIVQR 

« Hide

References

[1]"Homo sapiens protein coding cDNA."
Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Spleen EMBL BAD92879.1.
[2]"Structural factors contributing to the Abl/Lyn dual inhibitory activity of 3-substituted benzamide derivatives."
Horio T., Hamasaki T., Inoue T., Wakayama T., Itou S., Naito H., Asaki T., Hayase H., Niwa T.
Bioorg. Med. Chem. Lett. 17:2712-2717(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 68-334.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB209642 mRNA. Translation: BAD92879.1.
UniGeneHs.431048.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2E2BX-ray2.20A/B68-334[»]
ProteinModelPortalQ59F19.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ59F19.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG102468.

Family and domain databases

InterProIPR015015. F-actin_binding.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
[Graphical view]
PfamPF08919. F_actin_bind. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSPR00109. TYRKINASE.
SMARTSM00808. FABD. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ59F19_HUMAN
AccessionPrimary (citable) accession number: Q59F19
Entry history
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.