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Protein

Carboxypeptidase

Gene

PPGB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotationSAAS annotation, Hydrolase, Protease

Protein family/group databases

ESTHERihuman-CTSA. Carboxypeptidase_S10.

Names & Taxonomyi

Protein namesi
Recommended name:
CarboxypeptidaseUniRule annotation (EC:3.4.16.-UniRule annotation)
Gene namesi
Name:PPGBImported
ORF Names:hCG_38374Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 45Sequence analysisAdd BLAST45
ChainiPRO_500770489746 – 497CarboxypeptidaseSequence analysisAdd BLAST452

Proteomic databases

PeptideAtlasiQ59EV6.
PRIDEiQ59EV6.

Expressioni

Gene expression databases

BgeeiENSG00000064601.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000361562.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1282. Eukaryota.
COG2939. LUCA.
HOGENOMiHOG000198295.
HOVERGENiHBG053652.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR033124. Ser_caboxypep_his_AS.
IPR018202. Ser_caboxypep_ser_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 2 hits.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59EV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSPRAPPG EQGRGGAEMI RAAPPPLFLL LLLLLLVSWA SRGEAAPDQD
60 70 80 90 100
EIQRLPGLAK QPSFRQYSGY LKGSGSKHLH YWFVESQKDP ENSPVVLWLN
110 120 130 140 150
GGPGCSSLDG LLTEHGPFLV QPDGVTLEYN PYSWNLIANV LYLESPAGVG
160 170 180 190 200
FSYSDDKFYA TNDTEVAQSN FEALQDFFRL FPEYKNNKLF LTGESYAGIY
210 220 230 240 250
IPTLAVLVMQ DPSMNLQGLA VGNGLSSYEQ NDNSLVYFAY YHGLLGNRLW
260 270 280 290 300
SSLQTHCCSQ NKCNFYDNKD LECVTNLQEV ARIVGNSGLN IYNLYAPCAG
310 320 330 340 350
GVPSHFRYEK DTVVVQDLGN IFTRLPLKRM WHQALLRSGD KVRMDPPCTN
360 370 380 390 400
TTAASTYLNN PYVRKALNIP EQLPQWDMCN FLVNLQYRRL YRSMNSQYLK
410 420 430 440 450
LLSSQKYQIL LYNGDVDMAC NFMGDEWFVD SLNQKMEVQR RPWLVKYGDS
460 470 480 490
GEQIAGFVKE FSHIAFLTIK GAGHMVPTDK PLAAFTMFSR FLNKQPY
Length:497
Mass (Da):56,120
Last modified:April 26, 2005 - v1
Checksum:iDE54B23F0EFF02E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209705 mRNA. Translation: BAD92942.1.
CH471077 Genomic DNA. Translation: EAW75789.1.
UniGeneiHs.609336.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209705 mRNA. Translation: BAD92942.1.
CH471077 Genomic DNA. Translation: EAW75789.1.
UniGeneiHs.609336.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000361562.

Protein family/group databases

ESTHERihuman-CTSA. Carboxypeptidase_S10.

Proteomic databases

PeptideAtlasiQ59EV6.
PRIDEiQ59EV6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1282. Eukaryota.
COG2939. LUCA.
HOGENOMiHOG000198295.
HOVERGENiHBG053652.

Miscellaneous databases

ChiTaRSiCTSA. human.

Gene expression databases

BgeeiENSG00000064601.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR033124. Ser_caboxypep_his_AS.
IPR018202. Ser_caboxypep_ser_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 2 hits.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00560. CARBOXYPEPT_SER_HIS. 1 hit.
PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ59EV6_HUMAN
AccessioniPrimary (citable) accession number: Q59EV6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 30, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.