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Protein
Submitted name:

F-box protein FBW7 isoform 2 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ59ET6

Names & Taxonomyi

Protein namesi
Submitted name:
F-box protein FBW7 isoform 2 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ59ET6

Structurei

3D structure databases

ProteinModelPortaliQ59ET6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 241F-boxInterPro annotationAdd BLAST47
Domaini293 – 576WD_REPEATS_REGIONInterPro annotationAdd BLAST284
Repeati308 – 333WDPROSITE-ProRule annotationAdd BLAST26
Repeati334 – 373WDPROSITE-ProRule annotationAdd BLAST40
Repeati374 – 413WDPROSITE-ProRule annotationAdd BLAST40
Repeati414 – 453WDPROSITE-ProRule annotationAdd BLAST40
Repeati454 – 493WDPROSITE-ProRule annotationAdd BLAST40
Repeati494 – 533WDPROSITE-ProRule annotationAdd BLAST40
Repeati537 – 576WDPROSITE-ProRule annotationAdd BLAST40

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0274 Eukaryota
ENOG410XRWX LUCA
HOVERGENiHBG051596

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
PF00400 WD40, 7 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SM00320 WD40, 8 hits
SUPFAMiSSF50978 SSF50978, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit
PS00678 WD_REPEATS_1, 5 hits
PS50082 WD_REPEATS_2, 7 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Fragment.

Q59ET6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PRSGLILSCI CLYCGVLLPV LLPNLPFLTC LSMSTLESVT YLPEKGLYCQ
60 70 80 90 100
RLPSSRTHGG TESLKGKNTE NMGFYGTLKM IFYKMKRKLD HGSEVRSFSL
110 120 130 140 150
GKKPCKVSEY TSTTGLVPCS ATPTTFGDLR AANGQGQQRR RITSVQPPTG
160 170 180 190 200
LQEWLKMFQS WSGPEKLLAL DELIDSCEPT QVKHMMQVIE PQFQRDFISL
210 220 230 240 250
LPKELALYVL SFLEPKDLLQ AAQTCRYWRI LAEDNLLWRE KCKEEGIDEP
260 270 280 290 300
LHIKRRKVIK PGFIHSPWKS AYIRQHRIDT NWRRGELKSP KVLKGHDDHV
310 320 330 340 350
ITCLQFCGNR IVSGSDDNTL KVWSAVTGKC LRTLVGHTGG VWSSQMRDNI
360 370 380 390 400
IISGSTDRTL KVWNAETGEC IHTLYGHTST VRCMHLHEKR VVSGSRDATL
410 420 430 440 450
RVWDIETGQC LHVLMGHVAA VRCVQYDGRR VVSGAYDFMV KVWDPETETC
460 470 480 490 500
LHTLQGHTNR VYSLQFDGIH VVSGSLDTSI RVWDVETGNC IHTLTGHQSL
510 520 530 540 550
TSGMELKDNI LVSGNADSTV KIWDIKTGQC LQTLQGPNKH QSAVTCLQFN
560 570 580 590 600
KNFVITSSDD GTVKLWDLKT GEFIRNLVTL ESGGSGGVVW RIRASNTKLV
610 620
CAVGSRNGTE ETKLLVLDFD VDMK
Length:624
Mass (Da):69,991
Last modified:April 26, 2005 - v1
Checksum:i2850F0F78C2039E1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209725 mRNA Translation: BAD92962.1
UniGeneiHs.561245
Hs.717081

Similar proteinsi

Entry informationi

Entry nameiQ59ET6_HUMAN
AccessioniPrimary (citable) accession number: Q59ET6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: May 23, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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