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Q59ET6

- Q59ET6_HUMAN

UniProt

Q59ET6 - Q59ET6_HUMAN

Protein
Submitted name:

F-box protein FBW7 isoform 2 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    SignaLinkiQ59ET6.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    F-box protein FBW7 isoform 2 variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: HPA

    Expressioni

    Gene expression databases

    ArrayExpressiQ59ET6.
    BgeeiQ59ET6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ59ET6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 F-box domain.UniRule annotation

    Keywords - Domaini

    RepeatUniRule annotation, WD repeatUniRule annotation

    Phylogenomic databases

    HOVERGENiHBG051596.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00256. FBOX. 1 hit.
    SM00320. WD40. 8 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    SSF81383. SSF81383. 1 hit.
    PROSITEiPS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 5 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q59ET6-1 [UniParc]FASTAAdd to Basket

    « Hide

    PRSGLILSCI CLYCGVLLPV LLPNLPFLTC LSMSTLESVT YLPEKGLYCQ    50
    RLPSSRTHGG TESLKGKNTE NMGFYGTLKM IFYKMKRKLD HGSEVRSFSL 100
    GKKPCKVSEY TSTTGLVPCS ATPTTFGDLR AANGQGQQRR RITSVQPPTG 150
    LQEWLKMFQS WSGPEKLLAL DELIDSCEPT QVKHMMQVIE PQFQRDFISL 200
    LPKELALYVL SFLEPKDLLQ AAQTCRYWRI LAEDNLLWRE KCKEEGIDEP 250
    LHIKRRKVIK PGFIHSPWKS AYIRQHRIDT NWRRGELKSP KVLKGHDDHV 300
    ITCLQFCGNR IVSGSDDNTL KVWSAVTGKC LRTLVGHTGG VWSSQMRDNI 350
    IISGSTDRTL KVWNAETGEC IHTLYGHTST VRCMHLHEKR VVSGSRDATL 400
    RVWDIETGQC LHVLMGHVAA VRCVQYDGRR VVSGAYDFMV KVWDPETETC 450
    LHTLQGHTNR VYSLQFDGIH VVSGSLDTSI RVWDVETGNC IHTLTGHQSL 500
    TSGMELKDNI LVSGNADSTV KIWDIKTGQC LQTLQGPNKH QSAVTCLQFN 550
    KNFVITSSDD GTVKLWDLKT GEFIRNLVTL ESGGSGGVVW RIRASNTKLV 600
    CAVGSRNGTE ETKLLVLDFD VDMK 624
    Length:624
    Mass (Da):69,991
    Last modified:April 26, 2005 - v1
    Checksum:i2850F0F78C2039E1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209725 mRNA. Translation: BAD92962.1.
    UniGeneiHs.561245.
    Hs.717081.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209725 mRNA. Translation: BAD92962.1 .
    UniGenei Hs.561245.
    Hs.717081.

    3D structure databases

    ProteinModelPortali Q59ET6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG051596.

    Enzyme and pathway databases

    SignaLinki Q59ET6.

    Gene expression databases

    ArrayExpressi Q59ET6.
    Bgeei Q59ET6.

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00256. FBOX. 1 hit.
    SM00320. WD40. 8 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    SSF81383. SSF81383. 1 hit.
    PROSITEi PS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 5 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ59ET6_HUMAN
    AccessioniPrimary (citable) accession number: Q59ET6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.