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Q59ET6

- Q59ET6_HUMAN

UniProt

Q59ET6 - Q59ET6_HUMAN

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Protein
Submitted name: F-box protein FBW7 isoform 2 variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ59ET6.

Names & Taxonomyi

Protein namesi
Submitted name:
F-box protein FBW7 isoform 2 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: HPA
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ59ET6.
BgeeiQ59ET6.

Structurei

3D structure databases

ProteinModelPortaliQ59ET6.

Family & Domainsi

Sequence similaritiesi

Contains 1 F-box domain.UniRule annotation

Keywords - Domaini

RepeatUniRule annotation, WD repeatUniRule annotation

Phylogenomic databases

HOVERGENiHBG051596.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEiPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59ET6-1 [UniParc]FASTAAdd to Basket

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PRSGLILSCI CLYCGVLLPV LLPNLPFLTC LSMSTLESVT YLPEKGLYCQ    50
RLPSSRTHGG TESLKGKNTE NMGFYGTLKM IFYKMKRKLD HGSEVRSFSL 100
GKKPCKVSEY TSTTGLVPCS ATPTTFGDLR AANGQGQQRR RITSVQPPTG 150
LQEWLKMFQS WSGPEKLLAL DELIDSCEPT QVKHMMQVIE PQFQRDFISL 200
LPKELALYVL SFLEPKDLLQ AAQTCRYWRI LAEDNLLWRE KCKEEGIDEP 250
LHIKRRKVIK PGFIHSPWKS AYIRQHRIDT NWRRGELKSP KVLKGHDDHV 300
ITCLQFCGNR IVSGSDDNTL KVWSAVTGKC LRTLVGHTGG VWSSQMRDNI 350
IISGSTDRTL KVWNAETGEC IHTLYGHTST VRCMHLHEKR VVSGSRDATL 400
RVWDIETGQC LHVLMGHVAA VRCVQYDGRR VVSGAYDFMV KVWDPETETC 450
LHTLQGHTNR VYSLQFDGIH VVSGSLDTSI RVWDVETGNC IHTLTGHQSL 500
TSGMELKDNI LVSGNADSTV KIWDIKTGQC LQTLQGPNKH QSAVTCLQFN 550
KNFVITSSDD GTVKLWDLKT GEFIRNLVTL ESGGSGGVVW RIRASNTKLV 600
CAVGSRNGTE ETKLLVLDFD VDMK 624
Length:624
Mass (Da):69,991
Last modified:April 26, 2005 - v1
Checksum:i2850F0F78C2039E1
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209725 mRNA. Translation: BAD92962.1.
UniGeneiHs.561245.
Hs.717081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB209725 mRNA. Translation: BAD92962.1 .
UniGenei Hs.561245.
Hs.717081.

3D structure databases

ProteinModelPortali Q59ET6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG051596.

Enzyme and pathway databases

SignaLinki Q59ET6.

Gene expression databases

ArrayExpressi Q59ET6.
Bgeei Q59ET6.

Family and domain databases

Gene3Di 2.130.10.10. 2 hits.
InterProi IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view ]
PRINTSi PR00320. GPROTEINBRPT.
SMARTi SM00256. FBOX. 1 hit.
SM00320. WD40. 8 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
SSF81383. SSF81383. 1 hit.
PROSITEi PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59ET6_HUMAN
AccessioniPrimary (citable) accession number: Q59ET6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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