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Protein
Submitted name:

Heterogeneous nuclear ribonucleoprotein M isoform a variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

RibonucleoproteinImported

Keywords - Ligandi

Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoprotein M isoform a variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Virion

PTM / Processingi

Proteomic databases

EPDiQ59ES8.
PaxDbiQ59ES8.
PeptideAtlasiQ59ES8.
PRIDEiQ59ES8.

Interactioni

Protein-protein interaction databases

IntActiQ59ES8. 1 interaction.
STRINGi9606.ENSP00000325376.

Structurei

3D structure databases

ProteinModelPortaliQ59ES8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini104 – 18178RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini538 – 61477RRM (RNA recognition motif)InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4212. Eukaryota.
COG0724. LUCA.
HOVERGENiHBG054880.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR024667. HnRNP_M.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PANTHERiPTHR23003:SF6. PTHR23003:SF6. 3 hits.
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59ES8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
NGSHLKTWLK KKGCAVVEFK MEESMKKAAE VLNKHSLSGR PLKVKEDPDG
60 70 80 90 100
EHARRAMQKV MATTGGMGMG PGGPGMITIP PSILNNPNIP NEIIHALQAG
110 120 130 140 150
RLGSTVFVAN LDYKVGWKKL KEVFSMAGVV VRADILEDKD GKSRGIGTVT
160 170 180 190 200
FEQSIEAVQA ISMFNGQLLF DRPMHVKMDE RALPKGDFFP PERPQQLPHG
210 220 230 240 250
LGGIGMGLGP GGQPIDANHL NKGIGMGNIG PAGMEGPFGG GMENMGRFGS
260 270 280 290 300
GMNMGRINEI LSNALKRGEI IAKQGGGGGG GSVPGIERMG PGIDRLGGAG
310 320 330 340 350
MERMGAGLGH GMDRVGSEIE RMGLVMDRMG SVERMGSGIE RMGPLGLDHM
360 370 380 390 400
ASSIERMGQT MERIGSGVER MGAGMGFGLE RMAAPIDRVG QTIERMGSGV
410 420 430 440 450
ERMGPAIERM GLSMERMVPA GMGAGLERMG PVMDRMATGL ERMGANNLER
460 470 480 490 500
MGLERMGANS LERMGLERMG ANSLERMGPA MGPALGAGIE RMGLAMGGGG
510 520 530 540 550
GASFDRAIEM ERGNFGGSFA GSFGGAGGHA PGVARKACQI FVRNLPFDFT
560 570 580 590 600
WKMLKDKFNE CGHVLYADIK MENGKSKGCG VVKFESPEVA ERACRMMNGM
610
KLSGREIDVR IDRNA
Length:615
Mass (Da):65,255
Last modified:April 26, 2005 - v1
Checksum:i042BDED33B19FE1E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209733 mRNA. Translation: BAD92970.1.
RefSeqiNP_001284347.1. NM_001297418.1.
UniGeneiHs.465808.
Hs.666214.

Genome annotation databases

GeneIDi4670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209733 mRNA. Translation: BAD92970.1.
RefSeqiNP_001284347.1. NM_001297418.1.
UniGeneiHs.465808.
Hs.666214.

3D structure databases

ProteinModelPortaliQ59ES8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ59ES8. 1 interaction.
STRINGi9606.ENSP00000325376.

Proteomic databases

EPDiQ59ES8.
PaxDbiQ59ES8.
PeptideAtlasiQ59ES8.
PRIDEiQ59ES8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4670.

Organism-specific databases

CTDi4670.

Phylogenomic databases

eggNOGiKOG4212. Eukaryota.
COG0724. LUCA.
HOVERGENiHBG054880.

Miscellaneous databases

GenomeRNAii4670.

Family and domain databases

Gene3Di3.30.70.330. 3 hits.
InterProiIPR024667. HnRNP_M.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PANTHERiPTHR23003:SF6. PTHR23003:SF6. 3 hits.
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ59ES8_HUMAN
AccessioniPrimary (citable) accession number: Q59ES8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 6, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.