Q59EN5 (Q59EN5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Prosaposin variant EMBL BAD93013.1
Organism	Homo sapiens (Human) EMBL BAD93013.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	530 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	sphingolipid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	lysosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD93013.1

Sequences

	Sequence		Length	Mass (Da)
	Q59EN5 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 6CA1F0159B182BC9	FASTA	530	58,727
	10 20 30 40 50 60 DGAMYALFLL ASLLGAALAG PVLGLKECTR GSAVWCQNVK TASDCGAVKH CLQTVWNKPT 70 80 90 100 110 120 VKSLPCDICK DVVTAAGDML KDNATEEEIL VYLEKTCDWL PKPNMSASCK EIVDSYLPVI 130 140 150 160 170 180 LDIIKGEMSR PGEVCSALNL CESLQKHLAE LNHQKQLESN KIPELDMTEV VAPFMANIPL 190 200 210 220 230 240 LLYPQDGPRS KPQPKDNGDV CQDCIQMVTD IQTAVRTNST FVQALVEHVK EECDRLGPGM 250 260 270 280 290 300 ADICKNYISQ YSEIAIQMMM HMQDQQPKEI CALVGFCDEV KEMPMQTLVP AKVASKNVIP 310 320 330 340 350 360 ALELVEPIKK HEVPAKSDVY CEVCEFLVKE VTKLIDNNKT EKEILDAFDK MCSKLPKSLS 370 380 390 400 410 420 EECQEVVDTY GSSILSILLE EVSPELVCSM LHLCSGTRLP ALTVHVTQPK DGGFCEVCKK 430 440 450 460 470 480 LVGYLDRNLE KNSTKQEILA ALEKGCSFLP DPYQKQCDQF VAEYEPVLIE ILVEVMDPSF 490 500 510 520 530 VCLKIGACPS AHKPLLGTEK CIWGPSYWCQ NTETAAQCNA VEHCKRHVWN

References

[1]	"Homo sapiens protein coding cDNA." Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAD93013.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB209776 mRNA. Translation: BAD93013.1.
IPI	IPI00744835.
UniGene	Hs.523004.
3D structure databases
ProteinModelPortal	Q59EN5.
SMR	Q59EN5. Positions 63-143, 198-278, 318-490.
ModBase	Search...
Protein-protein interaction databases
STRING	Q59EN5.
Proteomic databases
PRIDE	Q59EN5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
GeneTree	ENSGT00530000063434.
HOVERGEN	HBG002617.
Gene expression databases
ArrayExpress	Q59EN5.
Family and domain databases
InterPro	IPR003119. SapA. IPR007856. SapB_1. IPR008138. SapB_2. IPR008373. Saposin. IPR011001. Saposin-like. IPR021165. Saposin_chordata. IPR008139. SaposinB. [Graphical view]
Gene3D	G3DSA:1.10.225.10. Saposin_like. 4 hits.
Pfam	PF02199. SapA. 2 hits. PF05184. SapB_1. 4 hits. PF03489. SapB_2. 4 hits. [Graphical view]
PIRSF	PIRSF002431. Saposin. 1 hit.
PRINTS	PR01797. SAPOSIN.
SMART	SM00162. SAPA. 2 hits. SM00741. SapB. 4 hits. [Graphical view]
SUPFAM	SSF47862. Saposin_like. 4 hits.
PROSITE	PS51110. SAP_A. 2 hits. PS50015. SAP_B. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q59EN5_HUMAN

Accession

Primary (citable) accession number: Q59EN5

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.