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Protein

Histone acetyltransferase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Acetyl-CoA + [histone] = CoA + acetyl-[histone].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Histone acetyltransferaseUniRule annotation (EC:2.3.1.48UniRule annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ59EJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MYST (SAS/MOZ) family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG053268.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo/shadow_dom.
IPR016197. Chromodomain-like.
IPR002717. HAT_MYST-type.
IPR025995. Tudor-knot.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51726. MYST_HAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59EJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PGLSKAPVYA ILIALAEILS VKDISGRKLF YVHYIDFNKR LDEWVTHERL
60 70 80 90 100
DLKKIQFPKK EAKTPTKNGL PGSRPGSPER EVKRKVEVVS PATPVPSETA
110 120 130 140 150
PASVFPQNGA ARRAVAAQPG RKRKSNCLGT DEDSQDSSDG IPSAPRMTGS
160 170 180 190 200
LVSDRSHDDI VTRMKNIECI ELGRHRLKPW YFSPYPQELT TLPVLYLCEF
210 220 230 240 250
CLKYGRSLKC LQRHLTKCDL RHPPGNEIYR KGTISFFEID GRKNKSYSQN
260 270 280 290 300
LCLLAKCFLD HKTLYYDTDP FLFYVMTEYD CKGFHIVGYF SKEKESTEDY
310 320 330 340 350
NVACILTLPP YQRRGYGKLL IEFSYELSKV EGKTGTPEKP LSDLGLLSYR
360 370 380 390 400
SYWSQTILEI LMGLKSESGE RPQITINEIS EITSIKKEDV ISTLQYLNLI
410 420 430 440
NYYKGQYILT LSEDIVDGHE RAMLKRLLRI DSKCLHFTPK DWSKRGKW
Length:448
Mass (Da):51,320
Last modified:April 26, 2005 - v1
Checksum:i1C935771F94E2CB1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209813 mRNA. Translation: BAD93050.1.
UniGeneiHs.397010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209813 mRNA. Translation: BAD93050.1.
UniGeneiHs.397010.

3D structure databases

ProteinModelPortaliQ59EJ8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG053268.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000953. Chromo/shadow_dom.
IPR016197. Chromodomain-like.
IPR002717. HAT_MYST-type.
IPR025995. Tudor-knot.
[Graphical view]
PfamiPF01853. MOZ_SAS. 1 hit.
PF11717. Tudor-knot. 1 hit.
[Graphical view]
SMARTiSM00298. CHROMO. 1 hit.
[Graphical view]
SUPFAMiSSF54160. SSF54160. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51726. MYST_HAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59EJ8_HUMAN
AccessioniPrimary (citable) accession number: Q59EJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 24, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.