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Protein
Submitted name:

Aldehyde dehydrogenase 1A1 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. oxidoreductase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aldehyde dehydrogenase 1A1 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiQ59EJ0.

Expressioni

Gene expression databases

BgeeiQ59EJ0.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ59EJ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000271505.
HOVERGENiHBG108515.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q59EJ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
IAEPVTCVPG AESEMSSSGT PDLPVLLTDL KIQYTKIFIN NEWHDSVSGK
60 70 80 90 100
KFPVFNPATE EELCQVEEGD KEDVDKAVKA ARQAFQIGSP WRTMDASERG
110 120 130 140 150
RLLYKLADLI ERDRLLLATM ESMNGGKLYS NAYLNDLAGC IKTLRYCAGW
160 170 180 190 200
ADKIQGRTIP IDGNFFTYTR HEPIGVCGQI IPWNFPLVML IWKIGPALSC
210 220 230 240 250
GNTVVVKPAE QTPLTALHVA SLIKEAGFPP GVVNIVPGYG PTAGAAISSH
260 270 280 290 300
MDIDKVAFTG STEVGKLIKE AAGKSNLKRV TLELGGKSPC IVLADADLDN
310 320 330
AVEFAHHGVF YHQGQCCIAA SRIFCGRINL
Length:330
Mass (Da):35,780
Last modified:April 26, 2005 - v1
Checksum:i66760F20977D134E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209821 mRNA. Translation: BAD93058.1.
UniGeneiHs.76392.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB209821 mRNA. Translation: BAD93058.1.
UniGeneiHs.76392.

3D structure databases

ProteinModelPortaliQ59EJ0.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ59EJ0.

Proteomic databases

PRIDEiQ59EJ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000271505.
HOVERGENiHBG108515.

Gene expression databases

BgeeiQ59EJ0.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Homo sapiens protein coding cDNA."
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ59EJ0_HUMAN
AccessioniPrimary (citable) accession number: Q59EJ0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: November 26, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.