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Q59EG8

- Q59EG8_HUMAN

UniProt

Q59EG8 - Q59EG8_HUMAN

Protein
Submitted name:

Proteasome 26S non-ATPase subunit 2 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. enzyme regulator activity Source: InterPro

    GO - Biological processi

    1. regulation of protein catabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Proteasome 26S non-ATPase subunit 2 variantImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. proteasome complex Source: UniProtKB-KW

    Keywords - Cellular componenti

    ProteasomeImported

    PTM / Processingi

    Proteomic databases

    PRIDEiQ59EG8.

    Interactioni

    Protein-protein interaction databases

    IntActiQ59EG8. 1 interaction.
    MINTiMINT-1373356.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000176022.
    HOVERGENiHBG001842.

    Family and domain databases

    InterProiIPR016643. 26S_Psome_Rpn1.
    IPR016024. ARM-type_fold.
    IPR002015. Proteasome/cyclosome_rpt.
    [Graphical view]
    PfamiPF01851. PC_rep. 2 hits.
    [Graphical view]
    PIRSFiPIRSF015965. 26S_Psome_Rpn1. 1 hit.
    SUPFAMiSSF48371. SSF48371. 4 hits.

    Sequencei

    Sequence statusi: Fragment.

    Q59EG8-1 [UniParc]FASTAAdd to Basket

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    AVAAEMEEGG RDKAPVQPQQ SPAAAPGGTD EKPSGKERRD AGDKDKEQEL    50
    SEEDKQLQDE LEMLVERLGE KDTSLYRPAL EELRRQIRSS TTSMTSVPKP 100
    LKFLRPHYGK LKEIYENMAP GENKRFAADI ISVLAMTMSG ERECLKYRLV 150
    GSQEELASWG HEYVRHLAGE VAKEWQELDD AEKVQREPLL TLVKEIVPYN 200
    MAHNAEHEAC DLLMEIEQVD MLEKDIDENA YAKVCLYLTS CVNYVPEPEN 250
    SALLCCALGV FRKFSRFPEA LRLALMLNDM ELVEDIFTSC KDVVVQKQMA 300
    FMLGRHGVFL ELSEDVEEYE DLTEIMSNVQ LNSNFLALAR ELDIMEPKVP 350
    DDIYKTHLEN NRFGGSGSQV DSARMNLASS FVNGFVNAAF GQDKLLTDDG 400
    NKWLYKNKDH GMLSAAASLG MILLWDVDGG LTQIDKYLYS SEDYIKSGAL 450
    LACGIVNSGV RNECDPALAL LSDYVLHNSN TMRLGSIFGL GLAYAGSNRE 500
    DVLTLLLPVM GDSKSSMEVA GVTALACGMI AVGSCNGDVT STILQTIMEK 550
    SETELKDTYA RWLPLGLGLN HLGKGEAIEA ILAALEVVSE PFRSFANTLV 600
    DVCAYAGSGN VLKVQQLLHI CSEHFDSKEK EEDKDKKEKK DKDKKEAPAD 650
    MGAHQGVAVL GIALIAMGEE IGAEMALRTF GHLLRYGEPT LRRAVPLALA 700
    LISVSNPRLN ILDTLSKFSH DADPEVSYNS IFAMGMVGSG TNNARLAAML 750
    RQLAQYHAKD PNNLFMVRLA QGLTHLGKGT LTLCPYHSDR QLMSQVAVAG 800
    LLTVLVSFLD VRNIILGKSH YVLYGLVAAM QPRMLVTFDE ELRPLPVSVR 850
    VGQAVDVVGQ AGKPKTITGF QTHTTPVLLA HGERAELATE EFLPVTPILE 900
    GFVILRKNPN YDL 913
    Length:913
    Mass (Da):100,588
    Last modified:April 26, 2005 - v1
    Checksum:iC450F8B4395A5938
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209843 mRNA. Translation: BAD93080.1.
    UniGeneiHs.518464.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB209843 mRNA. Translation: BAD93080.1 .
    UniGenei Hs.518464.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q59EG8. 1 interaction.
    MINTi MINT-1373356.

    Proteomic databases

    PRIDEi Q59EG8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000176022.
    HOVERGENi HBG001842.

    Family and domain databases

    InterProi IPR016643. 26S_Psome_Rpn1.
    IPR016024. ARM-type_fold.
    IPR002015. Proteasome/cyclosome_rpt.
    [Graphical view ]
    Pfami PF01851. PC_rep. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF015965. 26S_Psome_Rpn1. 1 hit.
    SUPFAMi SSF48371. SSF48371. 4 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Homo sapiens protein coding cDNA."
      Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Aorta endothelial cellImported.

    Entry informationi

    Entry nameiQ59EG8_HUMAN
    AccessioniPrimary (citable) accession number: Q59EG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 26, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.